• Netherlands

  • Netherlands

Research Output

Article

X-exome sequencing identifies a HDAC8 variant in a large pedigree with X-linked intellectual disability, truncal obesity, gynaecomastia, hypogonadism and unusual face

Harakalova, M., van den Boogaard, M. J., Sinke, R., van Lieshout, S., van Tuil, M. C., Duran, K., Renkens, I., Terhal, P. A., de Kovel, C., Nijman, I. J., van Haelst, M., Knoers, N. V., van Haaften, G., Kloosterman, W., Hennekam, R. C., Cuppen, E. & Ploos van Amstel, H. K., 2012, In : Journal of Medical Genetics. 49, 8, p. 539-543

Research output: Contribution to journal/periodicalArticleScientificpeer-review

X-linked H3K27me3 demethylase Utx is required for embryonic development in a sex-specific manner

Welstead, G. G., Creyghton, M. P., Bilodeau, S., Cheng, A. W., Markoulaki, S., Young, R. A. & Jaenisch, R., 2012, In : Proceedings of the National Academy of Sciences of the United States of America. 109, 32, p. 13004-13009

Research output: Contribution to journal/periodicalArticleScientificpeer-review

XPF-ERCC1 acts in Unhooking DNA interstrand crosslinks in cooperation with FANCD2 and FANCP/SLX4

Klein Douwel, D., Boonen, R. A. C. M., Long, D. T., Szypowska, A. A., Räschle, M., Walter, J. C. & Knipscheer, P., 08 May 2014, In : Molecular Cell. 54, 3, p. 460-71 12 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Xtcf-3 Transcription factor mediates beta-catenin-induced axis formation in xenopus embryos

Molenaar, M., Wetering, M. V. D., Oosterwegel, M., Peterson-Maduro, J., Godsave, S., Korinek, V., Roose, J., Destré, O. & Clevers, J. C., 1996, In : Cell. 86, p. 391-399

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access
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Xwnt8 directly initiates expression of labial Hox genes.

In der Rieden, P. M., Vilaspasa, F. L. & Durston, A. J., 2010, In : Developmental Dynamics. 239, 1, p. 126-139

Research output: Contribution to journal/periodicalArticleScientificpeer-review

X zonder kruisvorm

de Laat, W., 08 Nov 2013, In : C2W. p. 26

Research output: Contribution to journal/periodicalArticlePopularizing

YAP Drives Growth by Controlling Transcriptional Pause Release from Dynamic Enhancers

Galli, G. G., Carrara, M., Yuan, W-C., Valdes-Quezada, C., Gurung, B., Pepe-Mooney, B., Zhang, T., Geeven, G., Gray, N. S., de Laat, W., Calogero, R. A. & Camargo, F. D., 15 Oct 2015, In : Molecular Cell. 60, 2, p. 328-37 10 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

YAP Partially Reprograms Chromatin Accessibility to Directly Induce Adult Cardiogenesis In Vivo

Monroe, T. O., Hill, M. C., Morikawa, Y., Leach, J. P., Heallen, T., Cao, S., Krijger, P. H. L., de Laat, W., Wehrens, X. H. T., Rodney, G. G. & Martin, J. F., 25 Mar 2019, In : Developmental Cell. 48, 6, p. 765-779.e7

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Zebrafish as a cancer model.

Feitsma, H. & Cuppen, E., 2008, In : Molecular Cancer Research. 6, 5, p. 685-694

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Zebrafish as a model to study cardiac development and human cardiac disease

Bakkers, J., 2011, In : Cardiovascular Research. 91, 2, p. 279-288

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access
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Zebrafish as a model to study PTPs during development

Paardekooper Overman, J. & den Hertog, J., 15 Jan 2014, In : Methods. 65, 2, p. 247-53 7 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Zebrafish cypher is important for somite formation and heart development.

van der Meer, D. L., Marques, I. J., Leito, J. T., Besser, J., Bakkers, J., Schoonheere, E. & Bagowski, C. P., 2006, In : Developmental Biology. 299, 2, p. 356-372

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Zebrafish DeltaNp63 is a direct target of Bmp signaling and encodes a transcriptional repressor blocking neural specification in the ventral ectoderm.

Bakkers, J., Hild, M., Kramer, C., Furutani-Seiki, M. & Hammerschmidt, M., 2002, In : Developmental Cell. 2, 5, p. 617-627

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Zebrafish development and regeneration: new tools for biomedical research

Brittijn, S. A., Duivesteijn, S. J., Belmamoune, M., Bertens, L. F., Bitter, W., de Bruijn, J. D., Champagne, D. L., Cuppen, E., Flik, G., Vandenbroucke-Grauls, C. M., Janssen, R. A., De Jong, I. M., De Kloet, E. R., Kros, A., Meijer, A. H., Metz, J. R., Van der Sar, A. M., Schaaf, M. J., Schulte-Merker, S., Spaink, H. P. & 7 others, Tak, P. P., Verbeek, F. J., Vervoordeldonk, M. J., Vonk, F. J., Witte, F., Yuan, H. & Richardson, M. K., 2009, In : International Journal of Developmental Biology. 53, 5-6, p. 835-850

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access
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6792 Downloads (Pure)

Zebrafish enpp1 mutants exhibit pathological mineralization, mimicking features of generalized arterial calcification of infancy (GACI) and pseudoxanthoma elasticum (PXE)

Apschner, A., Huitema, L. F. A., Ponsioen, B., Peterson-Maduro, J. & Schulte-Merker, S., Jul 2014, In : Disease Models & Mechanisms. 7, 7, p. 811-22 12 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Zebrafish integrin-linked kinase is required in skeletal muscles for strengthening the integrin-ECM adhesion complex.

Postel, R., Vakeel, P., Topczewski, J., Knoll, R. & Bakkers, J., 2008, In : Developmental Biology. 318, 1, p. 92-101

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Zebrafish mutants in the von Hippel-Lindau tumor suppressor display a hypoxic response and recapitulate key aspects of Chuvash polycythemia

van Rooijen, E., Voest, E. E., Logister, I., Korving, J., Schwerte, T., Schulte-Merker, S., Giles, R. H. & van Eeden, F. J., 2009, In : Blood. 113, 25, p. 6449-6460

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Zebrafish provides a novel model for lymphatic vascular research

Karpanen, T. & Schulte-Merker, S., 2011, In : Methods in Cell Biology. 105, p. 223-238

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Zebrafish prox1b Mutants Develop a Lymphatic Vasculature, and prox1b Does Not Specifically Mark Lymphatic Endothelial Cells

Tao, S., de Witte, M., Bryson-Richardson, R. J., Currie, P. D., Hogan, B. M. & Schulte-Merker, S., 2011, In : PLoS One. 6, 12, p. 28934

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access
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Zebrafish pten genes have overlapping and non-redundant functions in tumorigenesis and embryonic development.

Faucherre, A. F. J. A., Taylor, G. S., Overvoorde, J., Dixon, J. E. & den Hertog, J., 2008, In : Oncogene. 27, 8, p. 1079-1086

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Zebrafish Tie-2 shares a redundant role with Tie-1 in heart development and regulates vessel integrity

Gjini, E., Hekking, L. H., Kuchler, A., Saharinen, P., Wienholds, E., Post, J., Alitalo, K. & Schulte-Merker, S., 2011, In : Disease Models & Mechanisms. 4, 1, p. 57-66

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access
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657 Downloads (Pure)

Zebrafish VEGF receptors: a guideline to nomenclature.

Bussmann, J., Lawson, N., Zon, L. & Schulte-Merker, S., 2008, In : PLoS Genetics. 4, 5

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Zebrafish with mutations in mismatch repair genes develop neurofibromas and other tumors.

Feitsma, H., Kuiper, R. V., Korving, J., Nijman, I. J. & Cuppen, E., 2008, In : Cancer Research. 68, 13, p. 5059-5066

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Zili is required for germ cell differentiation and meiosis in zebrafish.

Houwing, S., Berezikov, E. & Ketting, R. F., 2008, In : EMBO Journal. 27, 20, p. 2702-2711

Research output: Contribution to journal/periodicalArticleScientificpeer-review

ZNRF3 functions in mammalian sex determination by inhibiting canonical WNT signaling

Harris, A., Siggers, P., Corrochano, S., Warr, N., Sagar, D., Grimes, D. T., Suzuki, M., Burdine, R. D., Cong, F., Koo, B-K., Clevers, H., Stévant, I., Nef, S., Wells, S., Brauner, R., Ben Rhouma, B., Belguith, N., Eozenou, C., Bignon-Topalovic, J., Bashamboo, A. & 2 others, McElreavey, K. & Greenfield, A., 22 May 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 21, p. 5474-5479 6 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

α-catenin cytomechanics--role in cadherin-dependent adhesion and mechanotransduction

Barry, A. K., Tabdili, H., Muhamed, I., Wu, J., Shashikanth, N., Gomez, G. A., Yap, A. S., Gottardi, C. J., de Rooij, J., Wang, N. & Leckband, D. E., 15 Apr 2014, In : Journal of Cell Science. 127, Pt 8, p. 1779-91 13 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

αE-catenin-dependent mechanotransduction is essential for proper convergent extension in zebrafish

Han, M. K. L., Hoijman, E., Nöel, E., Garric, L., Bakkers, J. & de Rooij, J., 2016, In : Biology Open. 5, 10, p. 1461-1472 12 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

β-Cell Stress Shapes CTL Immune Recognition of Preproinsulin Signal Peptide by Posttranscriptional Regulation of Endoplasmic Reticulum Aminopeptidase 1

Thomaidou, S., Kracht, M. J. L., van der Slik, A., Laban, S., de Koning, E. J., Carlotti, F., Hoeben, R. C., Roep, B. O. & Zaldumbide, A., Apr 2020, In : Diabetes. 69, 4, p. 670-680 11 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

β-TrCP- and Casein Kinase II-Mediated Degradation of Cyclin F Controls Timely Mitotic Progression

Mavrommati, I., Faedda, R., Galasso, G., Li, J., Burdova, K., Fischer, R., Kessler, B. M., Carrero, Z. I., Guardavaccaro, D., Pagano, M. & D'Angiolella, V., 25 Sep 2018, In : Cell Reports. 24, 13, p. 3404-3412 9 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access
Book

CD3: Structural and genetic aspects of a cell surface glycoprotein complex

Hall, C., Alarcon, B., Berkhout, B., Clevers, J. C., Georgopoulos, K., Gold, D., Pettey, C., Elsen, P. V. D., Wileman, T. & Terhorst, C., 1987, Oxford: Oxford University Press.

Research output: Book/ReportBookScientific

Developmental Aspects of the Lymphatic Vascular System

Schulte-Merker, S. (ed.), 2013, [s.l.]: Springer.

Research output: Book/ReportBookScientific

Diabetes, what's up? De visie van Diabetes Nederland

van der Wiel, G. (ed.), 2012, Utrecht: Health Investment Utrecht.

Research output: Book/ReportBookScientific

Methods

de Laat, W. (ed.), 2012, Unknown: Elsevier B.V.

Research output: Book/ReportBookScientific

Special Issue

Korswagen, H. C. (ed.), 2009, Utrecht: Universiteit Utrecht.

Research output: Book/ReportBookScientific

Synergistic action of A23187 and PMA on B cells in CLL

Clevers, J. C., Versteegen, J. M. T., Gmelig-Meyling, F. H. J. & Ballieux, R. E., 1986, Elsevier B.V.

Research output: Book/ReportBookScientific

File
56 Downloads (Pure)
Chapter

Computational methods for the identification of mciroRNAs from small RNA sequencing data

Berezikov, E., 2011, Tag-based Next Generation Sequencing. Harbers, M. & Kahl, G. (eds.).

Research output: Chapter in book/volumeChapterScientific

Eilandjes van langerhans H18

de Koning, E., 2013, Canon van de Endocrinologie. de Herder, W. & van der Daan, H. (eds.). DCHG Medische Communicatie, p. 54

Research output: Chapter in book/volumeChapterScientific

FilterFRET: quantitative imaging of sensitized emission

Jalink, K. & van Rheenen, J., 2009, Laboratory techniques in biochemistry and molecular biology. Gadella, T. W. J. (ed.). Burlington: Academic Press, Vol. 33. p. 289-349 (FRET and FLIM techniques).

Research output: Chapter in book/volumeChapterScientific

Generation of Genetically Modified Rodents Using Random ENU Mutagenesis

van Boxtel, R. & Cuppen, E., 2011, Transgenic Mouse Methods and Protocols. Humana Press, p. 295-308

Research output: Chapter in book/volumeChapterScientific

MicroRNA Biogenesis and Function: An overview

Ketting, R. F., 2011, Regulation of microRNAs Ed: H Grosshans Landes Bioscience and Springer. Großhans, H. (ed.). Springer, Vol. 700. 160 p. (Advances in Experimental Medicine and Biology).

Research output: Chapter in book/volumeChapterScientific

New animal models of lymphangiogenesis

Schulte-Merker, S. & Hogan, B. M., 2009, Lymphangiogenesis in cancer metastasis. Springer, p. 27-54 (vol. 13).

Research output: Chapter in book/volumeChapterScientific

Stamceltherapie maakt eerste beloften waar

Clevers, H., 2010, Gezondgids.

Research output: Chapter in book/volumeChapterScientific

The TGB-β family in endothelial cell differentiation and cardiovascular development and function

Goumans, M. J., Carvalho, R., Mummery, C. L. & ten Dijke, P., 2008, The TGB-β family. Derynck, R. & Miyazono, K. (eds.). Cold Spring Harbor, p. 761-788

Research output: Chapter in book/volumeChapterScientific

Transplantatie van eilandjes van Langerhans

de Koning, E. & Bavinck, W., 2013, Gids voor orgaantransplantatie en donatie. De Tijdstroom, p. 185-187

Research output: Chapter in book/volumeChapterScientific

Zebrafish and phosphatase function

den Hertog, J., 2009, Handbook of Cell Signaling Chapter 101. Bradshaw, R. & Dennis, E. (eds.).

Research output: Chapter in book/volumeChapterScientific

Zebrafish Models of Cancer

MacInnes, A. W., Amsterdam, A., Hopkins, N. & Lees, J., 2012, Cancer: The Outlaw Cell. Richard LaFond

Research output: Chapter in book/volumeChapterScientific

Contribution to conference proceedings

Galectin-1 is essential in tumor angiogenesis and is a target for antiangiogenesis therapy.

Thijssen, V. L., Postel, R., Brandwijk, R. J., Dings, R. P., Nesmelova, I., Satijn, S., Verhofstad, N., Nakabeppu, Y., Baum, L. G., Bakkers, J., Mayo, K. H., Poirier, F. & Griffioen, A. W., 2006, Proceedings of the National Academy of Sciences of the United States of America. p. 15975-15980

Research output: Chapter in book/volumeContribution to conference proceedingsScientific

Patent
PhD thesis

A bone to pick with zebrafish: chemistry and genetics of osteogenesis

Mackay, E., 25 Nov 2014, Utrecht: Utrecht University. 128 p.

Research output: PhD ThesisPhD thesis

Aduld Stem Cells in Mice

Snippert, H. J. G., 2011

Research output: PhD ThesisPhD thesis