• Netherlands

  • Netherlands

Research Output

2009

Dendra2 photoswitching through the Mammary Imaging Window

Gligorijevic, B., Kedrin, D., Segall, J. E., Condeelis, J. & van Rheenen, J., 2009, In : Journal of Visualized Experiments. 28

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Dietary sources of lignans and isoflavones modulate responses to estradiol in estrogen reporter mice

Penttinen-Damdimopoulou, P. E., Power, K. A., Hurmerinta, T. T., Nurmi, T., van der Saag, P. T. & Makela, S. I., 2009, In : Molecular nutrition & food research. 53, 8, p. 996-1006

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Distinct gene mutation profiles among luminal-type and basal-type breast cancer cell lines

Hollestelle, A., Nagel, J. H., Smid, M., Lam, S., Elstrodt, F., Wasielewski, M., Ng, S. S., French, P. J., Peeters, J. K., Rozendaal, M. J., Riaz, M., Koopman, D. G., Ten Hagen, T. L., De Leeuw, B. H., Zwarthoff, E. C., Teunisse, A., Van der Spek, P. J., Klijn, J. G., Dinjens, W. N., Ethier, S. P. & 6 others, Clevers, H., Jochemsen, A. G., Den Bakker, M. A., Foekens, J. A., Martens, J. W. & Schutte, M., 2009, In : Breast Cancer Research and Treatment.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Distinct phases of cardiomyocyte differentiation regulate growth of the zebrafish heart.

de Pater, E. M., Clijsters, L., Marques, S. R., Lin, Y. F., Garavito-Aguilar, Z. V., Yelon, D. & Bakkers, J., 2009, In : Development. 136, 10, p. 1633-1641

Research output: Contribution to journal/periodicalArticleScientificpeer-review

DNA repair mechanisms in C. elegans

Brouwer, K., 2009, Utrecht: Universiteit Utrecht.

Research output: PhD ThesisPhD thesis

Dominant-negative ALK2 allele associates with congenital heart defects.

Smith, K., Joziasse, I. C., Chocron, S., van Dinther, M., Guryev, V., Verhoeven, M. C., Rehmann, H., van der Smagt, J. J., Doevendans, P. A., Cuppen, E., Mulder, B. J. M., ten Dijke, P. & Bakkers, J., 2009, In : Circulation. 119, 24, p. 3062-3069

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Eyeing up new Wnt pathway players.

Clevers, H., 2009, In : Cell. 139, 2, p. 227-229

Research output: Contribution to journal/periodicalArticleScientificpeer-review

FilterFRET: quantitative imaging of sensitized emission

Jalink, K. & van Rheenen, J., 2009, Laboratory techniques in biochemistry and molecular biology. Gadella, T. W. J. (ed.). Burlington: Academic Press, Vol. 33. p. 289-349 (FRET and FLIM techniques).

Research output: Chapter in book/volumeChapterScientific

Fine-tuning the brain: MicroRNAs

Vreugdenhil, E. & Berezikov, E., 2009, In : Frontiers in Neuroendocrinology.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Fishing for Intestinal Cancer Models: Unraveling Gastrointestinal Homeostasis and Tumorigenesis in Zebrafish

Faro, A., Boj, S. F. & Clevers, H., 2009, In : Zebrafish.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Functional analyses of human and zebrafish 18-amino acid in-frame deletion pave the way for domain mapping of the cerebral cavernous malformation 3 protein

Voss, K., Stahl, S., Hogan, B. M., Reinders, J., Schleider, E., Schulte-Merker, S. & Felbor, U., 2009, In : Human Mutation. 30, 6, p. 1003-1011

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Generation and characterization of FMR1 knockout zebrafish.

den Broeder, M. J., van der Linde, H., de Brouwer, J. F. C., Oostra, B. A., Willemsen, R. & Ketting, R. F., 2009, In : PLoS One. 4, 11

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Genetic analysis and in vivo imaging of vascular development in the zebrafish

Bussmann, J., 2009, Universiteit Utrecht. 100 p.

Research output: PhD ThesisPhD thesis

HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction

Ye, F., Chen, Y., Hoang, T., Montgomery, R. L., Zhao, X. H., Bu, H., Hu, T., Taketo, M. M., van Es, J. H., Clevers, H., Hsieh, J., Bassel-Duby, R., Olson, E. N. & Lu, Q. R., 2009, In : Nature Neuroscience. 12, 7, p. 829-838

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Highly Efficient ENU Mutagenesis in Zebrafish.

de Bruijn, E., Cuppen, E. & Feitsma, H., 2009, In : Methods in Molecular Biology. 546, p. 3-12

Research output: Contribution to journal/periodicalArticleScientificpeer-review

High-resolution identification of balanced and complex chromosomal rearrangements by 4C technology.

Simonis, M., Klous, P., Homminga, I., Galjaard, R. J., Rijkers, E. J., Grosveld, F., Meijerink, J. P. & de Laat, W., 2009, In : Nature Methods. 6, 11, p. 837-842

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Hox, Cdx, and anteroposterior patterning in the mouse embryo.

Young, T. & Deschamps, J., 2009, In : Current Topics in Developmental Biology. 88, p. 235-255

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Human cardiomyocyte progenitor cell transplantation preserves long-term function of the infarcted mouse myocardium

Smits, A. J. M., van Laake, L. W., den Ouden, K., Schreurs, C., Szuhai, K., van Echteld, C. J., Mummery, C. L., Doevendans, P. A. & Goumans, M. J., 2009, In : Cardiovascular Research. 83, 3, p. 527-535

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Human stem cells as a model for cardiac differentiation and disease

Beqqali, A., van Eldik, W., Mummery, C. L. & Passier, R., 2009, In : Cellular and Molecular Life Sciences. 66, 5, p. 800-813

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Identification of primary MAFB target genes in multiple myeloma

Stralen, E., van de Wetering, M. L., Agnelli, L., Neri, A., Clevers, H. & Bast, B., 2009, In : Experimental Hematology. 37, 1, p. 78-86

Research output: Contribution to journal/periodicalArticleScientificpeer-review

In depth qualitative and quantitative profiling of tyrosine phosphorylation using a combination of phosphopeptide immuno-affinity purification and stable isotope dimethyl labeling

Boersema, P. J., Foong, L. Y., Ding, V. M., Lemeer, S., van Breukelen, B., Philp, R., Boekhorst, J., Snel, B., den Hertog, J., Choo, A. B. & Heck, A. J. R., 2009, In : Molecular and Cellular Proteomics.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Inflammatory bowel disease, stress, and the endoplasmic reticulum.

Clevers, H., 2009, In : New England Journal of Medicine. 360, 7, p. 726-727

Research output: Contribution to journal/periodicalArticleScientificpeer-review

In vivo activation of gene transcription via oestrogen response elements by a raloxifene analogue

Engdahl, C., Jochems, C., Gustafsson, J. A., van der Saag, P. T., Carlsten, H. & Lagerquist, M. K., 2009, In : Journal of Endocrinology. 203, 3, p. 349-356

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Isolation of deletion alleles by G4 DNA-induced mutagenesis.

Pontier, D. B., Kruisselbrink, E., Guryev, V. & Tijsterman, M., 2009, In : Nature Methods. 6, 9, p. 655-657

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Lef1 plays a role in patterning the mesoderm and ectoderm in Xenopus tropicalis

Roel, G., Gent, Y. Y., Peterson-Maduro, J., Verbeek, F. J. & Destree, O., 2009, In : International Journal of Developmental Biology. 53, 1, p. 81-89

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Limitations and possibilities of small RNA digital gene expression profiling

Linsen, S. E. V., de Wit, E., Janssens, G., Heater, S., Chapman, L., Parkin, R. K., Fritz, B., Wyman, S. K., de Bruijn, E., Voest, E. E., Kuersten, S., Tewari, M. & Cuppen, E., 2009, In : Nature Methods. 6, 7, p. 474-476

Research output: Contribution to journal/periodicalArticleScientificpeer-review

LKB1 and AMPK family signaling: the intimate link between cell polarity and energy metabolism.

Jansen, M., ten Klooster, J. P., Offerhaus, G. J. A. & Clevers, H., 2009, In : Physiological Reviews. 89, 3, p. 777-798

Research output: Contribution to journal/periodicalArticleScientificpeer-review

MafB oncoprotein detected by immunohistochemistry as a highly sensitive and specific marker for the prognostic unfavorable t(14;20) (q32;q12) in multiple myeloma patients

Stralen, E., Leguit, R. J., Begthel, H. L., Michaux, L., Buijs, A., Lemmens, H., Scheiff, J. M., Doyen, C., Pierre, P., Forget, F., Clevers, H. & Bast, B., 2009, In : Leukemia. 23, 4, p. 801-803

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Mammalian Wnt3a is released on lipoprotein particles

Neumann, S., Coudreuse, D. Y. M., van der Westhuyzen, D. R., Eckhardt, E. R., Korswagen, H. C., Schmitz, G. & Sprong, H., 2009, In : Traffic. 10, 3, p. 334-343

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Metastatic behaviour of primary human tumours in a zebrafish xenotransplantation model

Marques, I. J., Weiss, F. U., Vlecken, D. H., Nitsche, C., Bakkers, J., Lagendijk, A. K., Partecke, L. I., Heidecke, C. D., Lerch, M. M. & Bagowski, C. P., 2009, In : BMC Cancer. 9

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

Microalterations of inherently unstable genomic regions in rat mammary carcinomas as revealed by long oligonucleotide array-based comparative genomic hybridization

Adamovic, T., McAllister, D., Guryev, V., Wang, X., Andrae, J. W., Cuppen, E., Jacob, H. & Sugg, S. L., 2009, In : Cancer Research. 69, 12, p. 5159-5167

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Mst4 and Ezrin induce brush borders downstream of the Lkb1/Strad/Mo25 polarization complex.

ten Klooster, J. P., Jansen, M., Yuan, J., Oorschot, V., Begthel, H. L., di Giacomo, V., Colland, F., de Koning, J., Maurice, M. M., Hornbeck, P. & Clevers, H., 2009, In : Developmental Cell. 16, 4, p. 551-562

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Mutations in CCBE1 cause generalized lymph vessel dysplasia in humans.

Alders, M., Hogan, B. M., Gjini, E., Salehi, F., Al-Gazali, L., Hennekam, E. A., Holmberg, E. E., Mannens, M. M., Mulder, M. F., Offerhaus, G. J. A., Prescott, T. E., Schroor, E. J., Verheij, J. B., de Witte, M., Zwijnenburg, P. J., Vikkula, M., Schulte-Merker, S. & Hennekam, R., 2009, In : Nature Genetics. 41, 12, p. 1272-1274

Research output: Contribution to journal/periodicalArticleScientificpeer-review

New animal models of lymphangiogenesis

Schulte-Merker, S. & Hogan, B. M., 2009, Lymphangiogenesis in cancer metastasis. Springer, p. 27-54 (vol. 13).

Research output: Chapter in book/volumeChapterScientific

Next-generation sequencing approaches in genetic rodent model systems to study functional effects of human genetic variation.

Guryev, V. & Cuppen, E., 2009, In : FEBS Letters. 583, 11, p. 1668-1673

Research output: Contribution to journal/periodicalArticleScientificpeer-review

OLFM4 is a robust marker for stem cells in human intestine and marks a subset of colorectal cancer cells.

van der Flier, L. G., Haegebarth, A., Stange, D. E., van de Wetering, M. L. & Clevers, H., 2009, In : Gastroenterology. 137, 1, p. 15-17

Research output: Contribution to journal/periodicalArticleScientificpeer-review

p53 deletion impairs clearance of chromosomal-instable stem cells in aging telomere-dysfunctional mice

Begus-Nahrmann, Y., Lechel, A., Obenauf, A. C., Nalapareddy, K., Peit, E., Hoffmann, E., Schlaudraff, F., Liss, B., Schirmacher, P., Kestler, H., Danenberg, E. M., Barker, N., Clevers, H., Speicher, M. R. & Rudolph, K. L., 2009, In : Nature Genetics. 41, 10, p. 1138-1143

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Peroxisome proliferators - activated receptor (PPAR) regulation in cardiac metabolism and disease

el Azzouzi, H., 2009, Utrecht: Universiteit Utrecht. 128 p.

Research output: PhD ThesisPhD thesis

Phosphatidylinositol 3-kinase (PI3K) signaling does not activate the Wnt cascade

Ng, S. S., Mahmoudi, T., Danenberg, E. M., Bejaoui, I., de Lau, W. B. M., Korswagen, H. C., Schutte, M. & Clevers, H., 2009, In : Journal of Biological Chemistry. 284, 51, p. 35308-35313

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Phosphorylation dynamics during early differentiation of human embryonic stem cells

van Hoof, D., Munoz, J., Braam, S. R., Pinkse, M. W. H., Linding, R., Heck, A. J. R., Mummery, C. L. & Krijgsveld, J., 2009, In : Cell Stem Cell. 5, 2, p. 214-226

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Piwi-piRNA complexes in the zebrafish germline

Houwing, S., 2009, Utrecht: Universiteit Utrecht. 134 p.

Research output: PhD ThesisPhD thesis

Pmch expression during early development is critical for normal energy homeostasis

Mul, J. D., Yi, C. X., van den Berg, S. A., Ruiter, M., Toonen, P. W., van der Elst, M., Voshol, P. J., Ellenbroek, B. A., Kalsbeek, A., la Fleur, S. E. & Cuppen, E., 2009, In : American Journal of Physiology - Endocrinology and Metabolism.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Poor vessel formation in embryos from knock-in mice expressing ALK5 with L45 loop mutation defective in Smad activation

Itoh, F., Itoh, S., Carvalho, R., Adachi, T., Ema, M., Goumans, M. J., Larsson, J., Karlsson, S., Takahashi, S., Mummery, C. L., ten Dijke, P. & Kato, M., 2009, In : Laboratory Investigation. 89, 7, p. 800-810

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Potential role of miR-29b in modulation of Dnmt3a and Dnmt3b expression in primordial germ cells of female mouse embryos

Takada, S., Berezikov, E., Choi, Y. L., Yamashita, Y. & Mano, H., 2009, In : RNA. 15, 8, p. 1507-1514

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Prominin-1/CD133 marks stem cells and early progenitors in mouse small intestine.

Snippert, H. J. G., van Es, J. H., van den Born, M. M. W., Begthel, H. L., Stange, D. E., Barker, N. & Clevers, H., 2009, In : Gastroenterology. 136, 7, p. 2181-2187

Research output: Contribution to journal/periodicalArticleScientificpeer-review

RDE-1 slicer activity is required only for passenger-strand cleavage during RNAi in Caenorhabditis elegans.

Steiner, F. A., Okihara, K. L., Hoogstrate, S. W., Sijen, T. & Ketting, R. F., 2009, In : Nature Structural & Molecular Biology. 16, 2, p. 207-211

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Regulation of neural development and adult brain hoemostasis in the zebrafish

Paridaen, J. T. M., 2009, Universiteit Utrecht. 172 p.

Research output: PhD ThesisPhD thesis

Regulation of slow and fast muscle myofibrillogenesis by Wnt/beta-catenin and myostatin signaling.

Tee, J. M., van Rooijen, C. R., Boonen, R. A. C. M. & Zivkovic, D., 2009, In : PLoS One. 4, 6

Research output: Contribution to journal/periodicalArticleScientificpeer-review