• Netherlands

  • Netherlands

Research Output

2008

Cooperative synergy between NFAT and MyoD regulates myogenin expression and myogenesis.

Armand, A. S., Bourajjaj, M., Martinez-Martinez, S., el Azzouzi, H., Da Costa Martins, P. A., Hatzis, P., Seidler, T., Redondo, J. M. & de Windt, L. J., 2008, In : Journal of Biological Chemistry. 283, 43, p. 29004-29010

Research output: Contribution to journal/periodicalArticleScientificpeer-review

d-Asb11 is an essential mediator of canonical Delta-Notch signalling.

Diks, S. H., Sartori da Silva, M. A., Hillebrands, J-L., Bink, R. J., Versteeg, H. H., van Rooijen, C., Brouwers, A. M., Chitnis, A. B., Peppelenbosch, M. P. & Zivkovic, D., 2008, In : Nature Cell Biology. 10, 10, p. 1190-1198

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Deoxycorticosterone acetate-salt mice exhibit blood pressure-independent sexual dimorphism.

Karatas, A., Hegner, B., de Windt, L. J., Luft, F. C., Schubert, C., Gross, V., Akashi, Y. J., Gurgen, D., Kintscher, U., da Costa Goncalves, A. C., Regitz-Zagrosek, V. & Dragun, D., 2008, In : Hypertension. 51, 4, p. 1177-1183

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Distinct functions for ERK1 and ERK2 in cell migration processes during zebrafish gastrulation.

Krens, S. F. G., He, S., Lamers, G. E. M., Meijer, A. H., Bakkers, J., Schmidt, T., Spaink, H. P. & Snaar-Jagalska, B. E., 2008, In : Developmental Biology. 319, 2, p. 370-383

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Distribution and functional impact of DNA copy number variation in the rat.

Guryev, V., Saar, K., Adamovic, T., Verheul, M., van Heesch, S., Cook, S., Pravenec, M., Aitman, T., Jacob, H., Shull, J. D., Hubner, N. & Cuppen, E., 2008, In : Nature Genetics. 40, 5, p. 538-545

Research output: Contribution to journal/periodicalArticleScientificpeer-review

DNA mismatch repair, genome instability and cancer in zebrafish

Feitsma, H., 2008, Amsterdam: F&N Boekservice. 142 p.

Research output: PhD ThesisPhD thesis

Endoglin-mediated vascular remodeling: mechanisms underlying hereditary hemorrhagic telangiectasia.

Lebrin, F. & Mummery, C. L., 2008, In : Trends in Cardiovascular Medicine. 18, 1, p. 25-32

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Enhanced cardiomyogenesis of human embryonic stem cells by a small molecular inhibitor of p38 MAPK.

Graichen, R., Xu, X., Braam, S. R., Balakrishnan, T., Norfiza, S., Sieh, S., Soo, S. Y., Tham, S. C., Mummery, C. L., Colman, A., Zweigerdt, R. & Davidson, B. P., 2008, In : Differentiation. 76, 4, p. 357-370

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Feeder-free culture of human embryonic stem cells in conditioned medium for efficient genetic modification

Braam, S. R., Denning, C., Matsa, E., Young, L. E., Passier, R. & Mummery, C. L., 2008, In : Nature Protocols. 3, p. 1435-1443

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Feeder-free monolayer cultures of human embryonic stem cells express an epithelial plasma membrane protein profile.

van Hoof, D., Braam, S. R., Dormeyer, W., Ward-van Oostwaard, D., Heck, A., Krijgsveld, J. & Mummery, C. L., 2008, In : Stem Cells. 26, 11, p. 2777-2781

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Ferruginol suppresses survival signaling pathways in androgen-independent human prostate cancer cells.

Bispo de Jesus, M., Zambuzzi, W. F., Ruela de Sousa, R. R., Areche, C., Santos de Souza, A. C., Aoyama, H., Schmeda-Hirschmann, G., Rodriguez, J. A., Monteiro de Souza Brito, A. R., Peppelenbosch, M. P., den Hertog, J., de Paula, E. & Ferreira, C. V., 2008, In : Biochimie. 90, 6, p. 843-854

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Food-associated estrogenic compounds induce estrogen receptor-mediated luciferase gene expression in transgenic male mice.

ter Veld, M. G. R., Zawadzka, E., van den Berg, J. H. J., van der Saag, P. T., Rietjens, I. M. C. M. & Murk, A. J., 2008, In : Chemico-Biological Interactions. 174, 2, p. 126-133

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Functionally distinct regulatory RNAs generated by bidirectional transcription and processing of microRNA loci.

Tyler, D. M., Okamura, K., Chung, W. J., Hagen, J. W., Berezikov, E., Hannon, G. J. & Lai, E. C., 2008, In : Genes & Development. 22, 1, p. 26-36

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Genes in congenital heart disease: atrioventricular valve formation.

Joziasse, I. C., van de Smagt, J. J., Smith, K., Bakkers, J., Sieswerda, G. J., Mulder, B. J. M. & Doevendans, P. A., 2008, In : Basic Research in Cardiology. 103, 3, p. 216-227

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Genetic analysis of the ciliary protein Lrrc50 and the von Hippel-Lindau tumor suppressor in zebrafish

van Rooijen, E., 2008, Amsterdam: F&N Boekservice. 178 p.

Research output: PhD ThesisPhD thesis

Genetic analysis of the two zebrafish patched homologues identifies novel roles for the hedgehog signaling pathway.

Koudijs, M. J., den Broeder, M. J., Groot, E. & van Eeden, F., 2008, In : BMC Developmental Biology. 8

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

Genome-wide pattern of TCF7L2/TCF4 chromatin occupancy in colorectal cancer cells.

Hatzis, P., van der Flier, L. G., van Driel, M. A., Guryev, V., Nielsen, F., Denissov, S., Nijman, I. J., Koster, J., Santo, E. E., Welboren, W., Versteeg, R., van de Wetering, M. L., Clevers, H. & Stunnenberg, H. G., 2008, In : Molecular and Cellular Biology. 28, 8, p. 2732-2744

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Heart spotting.

el Azzouzi, H. & de Windt, L. J., 2008, In : Basic Research in Cardiology. 103, 3, p. 228-231

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Hedgehog signaling plays a cell-autonomous role in maximizing cardiac developmental potential.

Thomas, N. A., Koudijs, M. J., van Eeden, F. J., Joyner, A. L. & Yelon, D., 2008, In : Development. 135, 22, p. 3789-3799

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Human embryonic stem cell-derived cardiomyocytes and cardiac repair in rodents.

van Laake, L. W., Passier, R., Doevendans, P. A. & Mummery, C. L., 2008, In : Circulation Research. 102, 9, p. 1008-1010

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Human embryonic stem cells as a model for cardiac gene discovery; from chip to chap

Beqqali, A., 2008, Amsterdam: F&N Boekservice. 154 p.

Research output: PhD ThesisPhD thesis

Identification and characterization of novel genexs by reverse and forward genetics in zebrafish

Postel, R., 2008, 120 p.

Research output: PhD ThesisPhD thesis

Improved generation of rat gene knockouts by target-selected mutagenesis in mismatch repair-deficient animals.

van Boxtel, R., Toonen, P. W., Verheul, M., van Roekel, H. S., Nijman, I. J., Guryev, V. & Cuppen, E., 2008, In : BMC Genomics. 9

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Improved genetic manipulation of human embryonic stem cells.

Braam, S. R., Denning, C., van den Brink, S., Kats, P., Hochstenbach, R., Passier, R. & Mummery, C. L., 2008, In : Nature Methods. 5, 5, p. 389-392

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Influence of cellular ERalpha/ERbeta ratio on the ERalpha-agonist induced proliferation of uman T47D breast cancer cells

Sotoca Covaleda, A. M., van den Berg, H., Vervoort, J., van der Saag, P. T., Strom, A., Gustafsson, J. A., Rietjens, I. & Murk, A. J., 2008, In : Toxicological Sciences. 105, p. 303-311

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Insulin redirects differentiation from cardiogenic mesoderm and endoderm to neuroectoderm in differentiating human embryonic stem cells.

Freund, C. M. A. H., Ward-van Oostwaard, D., Monshouwer-Kloots, J., van den Brink, S., van Rooijen, M. A., Xu, X., Zweigerdt, R., Mummery, C. L. & Passier, R., 2008, In : Stem Cells. 26, 3, p. 724-733

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Intravital imaging of metastatic behavior through a mammary imaging window

Kedrin, D., Gligorijevic, B., Wyckoff, J., Verkhusha, V. V., Condeelis, J., Segall, J. E. & van Rheenen, J., 2008, In : Nature Methods. 5, p. 1019-1021

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Investigation of Frizzled-5 during embryonic neural development in mouse.

Burns, C. J., Zhang, J., Brown, E. C., van Bibber, A. M., van Es, J. H., Clevers, H., Ishikawa, T. O., Taketo, M. M., Vetter, M. L. & Fuhrmann, S., 2008, In : Developmental Dynamics. 237, 6, p. 1614-1626

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Lack of DNA mismatch repair protein MSH6 in the rat results in hereditary non-polyposis colorectal cancer-like tumorigenesis.

van Boxtel, R., Toonen, P. W., van Roekel, H. S., Verheul, M., Smits, B. M., Korving, J., de Bruin, A. & Cuppen, E., 2008, In : Carcinogenesis. 29, 6, p. 1290-1297

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Lgr5 marks cycling, yet long-lived, hair follicle stem cells.

Jaks, V., Barker, N., Kasper, M., van Es, J. H., Snippert, H. J. G., Clevers, H. & Toftgard, R., 2008, In : Nature Genetics. 40, 11, p. 1291-1299

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Loss of Hoxb8 alters spinal dorsal laminae and sensory responses in mice.

Holstege, J. C., de Graaff, W. G. A. J., Hossaini, M., Cano, S. C., Jaarsma, D., van den Akker, E. & Deschamps, J., 2008, In : Proceedings of the National Academy of Sciences of the United States of America. 105, 17, p. 6338-6343

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2.

Riccio, O., van Gijn, M. E., Bezdek, A. C., Pellegrinet, L., van Es, J. H., Zimber-Strobl, U., Strobl, L. J., Honjo, T., Clevers, H. & Radtke, F., 2008, In : EMBO Reports. 9, 4, p. 377-383

Research output: Contribution to journal/periodicalArticleScientificpeer-review

LRRC50, a conserved ciliary protein implicated in polycystic kidney disease.

van Rooijen, E., Giles, R. H., Voest, E. E., van Rooijen, C., Schulte-Merker, S. & van Eeden, F., 2008, In : Journal of the American Society of Nephrology. 19, 6, p. 1128-1138

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Mapping protein pphosphorylation in zebrafish development

Lemeer, S., 2008, 144 p.

Research output: PhD ThesisPhD thesis

MicroRNA expression profiles of human leukemias.

Takada, S., Yamashita, Y., Berezikov, E., Hatanaka, H., Fujiwara, S., Kurashina, K., Watanabe, H., Enomoto, M., Soda, M., Choi, Y. L. & Mano, H., 2008, In : Leukemia. 22, 6, p. 1274-1278

Research output: Contribution to journal/periodicalArticleScientificpeer-review

miRNAs: small changes, widespread effects

Linsen, S. E. V., Tops, B. B. J. & Cuppen, E., 2008, In : Cell Research. 18, p. 1157-1159

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Mismatch repair deficiency does not enhance ENU mutagenesis in the zebrafish germ line.

Feitsma, H., de Bruijn, E., van de Belt, J., Nijman, I. J. & Cuppen, E., 2008, In : Mutagenesis. 23, 4, p. 325-329

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Mutagenic capacity of endogenous G4 DNA underlies genome instability in FANCJ-defective C. elegans.

Kruisselbrink, E., Guryev, V., Brouwer, K., Pontier, D. B., Cuppen, E. & Tijsterman, M., 2008, In : Current Biology. 18, 12, p. 900-905

Research output: Contribution to journal/periodicalArticleScientificpeer-review

NCAM induces CaMKIIalpha-mediated RPTPalpha phosphorylation to enhance its catalytic activity and neurite outgrowth.

Bodrikov, V., Sytnyk, V., Leshchyns'ka, I., den Hertog, J. & Schachner, M., 2008, In : Journal of Cell Biology. 182, 6, p. 1185-1200

Research output: Contribution to journal/periodicalArticleScientificpeer-review

NFATc2 is a necessary mediator of calcineurin-dependent cardiac hypertrophy and heart failure.

Bourajjaj, M., Armand, A. S., Da Costa Martins, P. A., Weijts, B., van der Nagel, R., Heeneman, S., Wehrens, X. H. & de Windt, L. J., 2008, In : Journal of Biological Chemistry. 283, 32, p. 22295-22303

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Nix: the cardiac Styx between life and death.

Da Costa Martins, P. A. & de Windt, L. J., 2008, In : Circulation. 117, 3, p. 338-340

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Online automated in vivo zebrafish phosphoproteomics: from large-scale analysis down to a single embryo.

Lemeer, S., Pinkse, M. W. H., Mohammed, S., van Breukelen, B., den Hertog, J., Slijper, M. & Heck, A., 2008, In : Journal of Proteome Research. 7, 4, p. 1555-1564

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Origins and fates of cardiovascular progenitor cells.

Wu, S. M., Chien, K. R. & Mummery, C. L., 2008, In : Cell. 132, 4, p. 537-543

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Phylogeny of Y chromosomes from bovine species

Nijman, I. J., van Boxtel, D. C. J., van Cann, L. M., Marnoch, Y., Cuppen, E. & Lenstra, J. A., 2008, In : Cladistics. 24, p. 723-726

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Phytoestrogen-mediated inhibition of the human T47D breast cancer cells depends on the ERalfpha/ERbeta ratio

Sotoca, A. M., Ratman, D., van der Saag, P. T., Strom, A., Gustafsson, J. A., Vervoort, J., Rietjens, I. M. C. M. & Murk, A. J., 2008, In : Journal of Steroid Biochemistry and Molecular Biology. 112, p. 171-178

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Piwi and piRNAs act upstream of an endogenous siRNA pathway to suppress Tc3 transposon mobility in the Caenorhabditis elegans germline.

Das, P. P., Bagijn, M. P., Goldstein, L. D., Woolford, J. R., Lehrbach, N. J., Sapetschnig, A., Buhecha, H. R., Gilchrist, M. J., Howe, K. L., Stark, R., Matthews, N., Berezikov, E., Ketting, R. F., Tavare, S. & Miska, E. A., 2008, In : Molecular Cell. 31, 1, p. 79-90

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Plasma membrane proteomics of human embryonic stem cells and human embryonal carcinoma cells.

Dormeyer, W., van Hoof, D., Braam, S. R., Heck, A. J. R., Mummery, C. L. & Krijgsveld, J., 2008, In : Journal of Proteome Research. 7, 7, p. 2936-2951

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Progress and prospects in rat genetics: a community view.

Aitman, T., Critser, J. K., Cuppen, E., Dominiczak, A., Fernandez-Suarez, X. M., Flint, J., Gauguier, D., Geurts, A. M., Gould, M., Harris, P. C., Holmdahl, R., Hubner, N., Izsvak, Z., Jacob, H., Kuramoto, T., Kwitek, A. E., Marrone, A., Mashimo, T., Moreno, C., Mullins, J. & 11 others, Mullins, L., Olsson, T., Pravenec, M., Riley, L., Saar, K., Serikawa, T., Shull, J. D., Szpirer, C., Twigger, S. N., Voigt, B. & Worley, K., 2008, In : Nature Genetics. 40, 5, p. 516-522

Research output: Contribution to journal/periodicalArticleScientificpeer-review