• Netherlands

  • Netherlands

Research Output

2008

Protein tyrosine phosphatases: regulatory mechanisms.

den Hertog, J., Ostman, A. & Bohmer, F. D., 2008, In : FEBS Journal. 275, 5, p. 831-847

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Proteome biology of stem cells: a new joint HUPO and ISSCR initiative.

Krijgsveld, J., Whetton, A. D., Lee, B. H., Lemischka, I., Oh, S., Pera, M., Mummery, C. L. & Heck, A. J. R., 2008, In : Molecular and Cellular Proteomics. 7, 1, p. 204-205

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Real time monitoring of BMP Smads transcriptional activity during mouse development.

Monteiro, R., Chuva de Sousa Lopes, S. M., Bialecka, M., De Boer, S. A., Zwijsen, A. & Mummery, C. L., 2008, In : Genesis. 46, 7, p. 335-346

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Recombinant vitronectin is a functionally defined substrate that supports human embryonic stem cell self-renewal via alphavbeta5 integrin.

Braam, S. R., Zeinstra, L. M., Litjens, S. H. M., Ward-van Oostwaard, D., van den Brink, S., van Laake, L. W., Lebrin, F., Kats, P., Hochstenbach, R., Passier, R., Sonnenberg, A. & Mummery, C. L., 2008, In : Stem Cells. 26, 9, p. 2257-2265

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Redox regulation of dimerization of the receptor protein-tyrosine phosphatases RPTPalpha, LAR, RPTPmu and CD45.

Groen, A. J., Overvoorde, J., van der Wijk, T. & den Hertog, J., 2008, In : FEBS Journal. 275, 10, p. 2597-2604

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Redundant roles for sox7 and sox18 in arteriovenous specification in zebrafish.

Herpers, R., van de Kamp, E., Duckers, H. J. & Schulte-Merker, S., 2008, In : Circulation Research. 102, 1, p. 12-15

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Retinoic acid and Cyp26b1 are critical regulators of osteogenesis in the axial skeleton.

Spoorendonk, K. M., Peterson-Maduro, J., Renn, J., Trowe, T., Kranenbarg, S., Winkler, C. & Schulte-Merker, S., 2008, In : Development. 135, 22, p. 3765-3774

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Rotation and asymmetric development of the zebrafish heart requires directed migration of cardiac progenitor cells.

Smith, K., Chocron, S., von der Hardt, S., de Pater, E. M., Soufan, A., Bussmann, J., Schulte-Merker, S., Hammerschmidt, M. & Bakkers, J., 2008, In : Developmental Cell. 14, 2, p. 287-297

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Serotonin transporter dosage modulates long-term decision-making in rat and human.

Homberg, J. R., van den Bos, R., den Heijer, E. J., Suer, R. & Cuppen, E., 2008, In : Neuropharmacology. 55, 1, p. 80-84

Research output: Contribution to journal/periodicalArticleScientificpeer-review

SNP and haplotype mapping for genetic analysis in the rat.

Saar, K., Beck, A., Bihoreau, M., Birney, E., Brocklebank, D., Chen, Y., Cuppen, E., Demonchy, S., Dopazo, J., Flicek, P., Foglio, M., Fujiyama, A., Gut, I. G., Gauguier, D., Guigo, R., Guryev, V., Heinig, M., Hummel, O., Jahn, N., Klages, S. & 29 others, Kren, V., Kube, M., Kuhl, H., Kuramoto, T., Kuroki, Y., Lechner, D., Lee, Y. A., Lopez-Bigas, N., Lathrop, G. M., Mashimo, T., Medina, I., Mott, R., Patone, G., Perrier-Cornet, J. A., Platzer, M., Pravenec, M., Reinhardt, R., Sakaki, Y., Schilhabel, M., Schulz, H., Serikawa, T., Shikhagaie, M., Tatsumoto, S., Taudien, S., Toyoda, A., Voigt, B., Zelenika, D., Zimdahl, H. & Hubner, N., 2008, In : Nature Genetics. 40, 5, p. 560-566

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Stem-cell-based therapy and lessons from the heart.

Passier, R., van Laake, L. W. & Mummery, C. L., 2008, In : Nature. 453, 7193, p. 322-329

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Stress-induced hyperthermia and basal body temperature are mediated by different 5-HT(1A) receptor populations: a study in SERT knockout rats.

Olivier, J., Cools, A. R., Olivier, B., Homberg, J. R., Cuppen, E. & Ellenbroek, B. A., 2008, In : European Journal of Pharmacology. 590, 1-3, p. 190-197

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Tailored Hox gene transcription and the making of the thumb.

Deschamps, J., 2008, In : Genes & Development. 22, 3, p. 293-296

Research output: Contribution to journal/periodicalArticleScientificpeer-review

The Atp1a1 gene from inbred Dahl salt sensitive rats does not contain the A1079T missense transversion.

Mokry, M. & Cuppen, E., 2008, In : Hypertension. 51, 4, p. 922-927

Research output: Contribution to journal/periodicalArticleScientificpeer-review

The intestinal stem cell.

Barker, N., van de Wetering, M. L. & Clevers, H., 2008, In : Genes & Development. 22, 14, p. 1856-1864

Research output: Contribution to journal/periodicalArticleScientificpeer-review

The mutation of the LEW.1AR1-iddm rat maps to the telomeric end of rat chromosome 1.

Weiss, H., Arndt, T., Jorns, A., Lenzen, S., Cuppen, E., Hedrich, H. J., Tiedge, M. & Wedekind, D., 2008, In : Mammalian Genome. 19, 4, p. 292-297

Research output: Contribution to journal/periodicalArticleScientificpeer-review

The receptor protein-tyrosine phosphatase, Dep1, acts in arterial/venous cell fate decisions in zebrafish development

Rodriguez Proserpi, F., Vacaru, A., Overvoorde, J. & den Hertog, J., 2008, In : Developmental Biology. 324, p. 122-130

Research output: Contribution to journal/periodicalArticleScientificpeer-review

The role of transcription factor MAFB in multiple myeloma

van Stralen, E., 2008, 148 p.

Research output: PhD ThesisPhD thesis

The TGB-β family in endothelial cell differentiation and cardiovascular development and function

Goumans, M. J., Carvalho, R., Mummery, C. L. & ten Dijke, P., 2008, The TGB-β family. Derynck, R. & Miyazono, K. (eds.). Cold Spring Harbor, p. 761-788

Research output: Chapter in book/volumeChapterScientific

The time is right: proteome biology of stem cells.

Whetton, A. D., Williamson, A. J. K., Krijgsveld, J., Lee, B. H., Lemischka, I., Oh, S., Pera, M., Mummery, C. L. & Heck, A. J. R., 2008, In : Cell Stem Cell. 2, 3, p. 215-217

Research output: Contribution to journal/periodicalArticleScientificpeer-review

The TWIST1 oncogene is a direct target of hypoxia-inducible factor-2alpha.

Gort, E. H., van Haaften, G., Verlaan, I., Groot, A. J., Plasterk, R., Shvarts, A., Suijkerbuijk, K. P. M., van Laar, T., van der Wall, E., Raman, V., van Diest, P. J., Tijsterman, M. & Vooijs, M., 2008, In : Oncogene. 27, 11, p. 1501-1510

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Two novel type II receptors mediate BMP signalling and are required to establish left-right asymmetry in zebrafish.

Monteiro, R., van Dinther, M., Bakkers, J., Wilkinson, R., Patient, R., ten Dijke, P. & Mummery, C. L., 2008, In : Developmental Biology. 315, 1, p. 55-71

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Wnt secretion and signaling in Caenorhabditis elegans

Yang, P. T., 2008, Amsterdam: F&N Boekservice. 154 p.

Research output: PhD ThesisPhD thesis

Wnt signaling requires retromer-dependent recycling of MIG-14/Wntless in Wnt-producing cells.

Yang, P. T., Lorenowicz, M. J., Silhankova, M., Coudreuse, D. Y. M., Betist, M. C. & Korswagen, H. C., 2008, In : Developmental Cell. 14, 1, p. 140-147

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Zebrafish as a cancer model.

Feitsma, H. & Cuppen, E., 2008, In : Molecular Cancer Research. 6, 5, p. 685-694

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Zebrafish integrin-linked kinase is required in skeletal muscles for strengthening the integrin-ECM adhesion complex.

Postel, R., Vakeel, P., Topczewski, J., Knoll, R. & Bakkers, J., 2008, In : Developmental Biology. 318, 1, p. 92-101

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Zebrafish pten genes have overlapping and non-redundant functions in tumorigenesis and embryonic development.

Faucherre, A. F. J. A., Taylor, G. S., Overvoorde, J., Dixon, J. E. & den Hertog, J., 2008, In : Oncogene. 27, 8, p. 1079-1086

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Zebrafish VEGF receptors: a guideline to nomenclature.

Bussmann, J., Lawson, N., Zon, L. & Schulte-Merker, S., 2008, In : PLoS Genetics. 4, 5

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Zebrafish with mutations in mismatch repair genes develop neurofibromas and other tumors.

Feitsma, H., Kuiper, R. V., Korving, J., Nijman, I. J. & Cuppen, E., 2008, In : Cancer Research. 68, 13, p. 5059-5066

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Zili is required for germ cell differentiation and meiosis in zebrafish.

Houwing, S., Berezikov, E. & Ketting, R. F., 2008, In : EMBO Journal. 27, 20, p. 2702-2711

Research output: Contribution to journal/periodicalArticleScientificpeer-review

2007

APCmin tumors need a SPARC

Gregorrieff, A. & Clevers, J. C., 2007, In : Gut. 56

Research output: Contribution to journal/periodicalArticleScientificpeer-review

c-Myb is required for progenitor cell homeostasis in colonic crypts

Malaterre, J., Carpinelli, M., Ernst, M., Alexander, W., Cooke, M., Sutton, S., Dworkin, S., Heakth, J. K., Frampton, J., McArthur, G., Clevers, J. C., Hilton, D., Mantamadiotis, T. & Ramsay, R. G., 2007, In : Proceedings of the National Academy of Sciences of the United States of America. 104, p. 3829-3834

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Identification of stem cells in small intestine and colon by marker gene Lgr5

Barker, N., Van Es, J. H., Kuipers, J., Kujala, P., Van Den Born, M., Cozijnsen, M., Haegebarth, A., Korving, J., Begthel, H., Peters, P. J. & Clevers, H., 25 Oct 2007, In : Nature. 449, 7165, p. 1003-1007 5 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE.

Vooijs, M., Ong, C. T., Hadland, B., Huppert, S., Liu, Z., Korving, J., Born, M. V. D., Stappenbeck, T., Wu, Y., Clevers, J. C. & Kopan, R., 2007, In : Development. 134, p. 535-544

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Myc deletion rescues Apc deficiency in the small intestine

Sansom, O. J., Meniel, V. S., Muncan, V., Phesse, T. J., Wilkins, J. A., Reed, K. R., Vass, J. K., Athineos, D., Clevers, J. C. & Clarke, A. R., 2007, In : Nature. 446, p. 676-679

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Secondary siRNAs result from unprimed RNA synthesis and form a distinct class.

Sijen, L. M. T., Steiner, F. A., Thijssen, K. L. & Plasterk, R. H. A., 2007, In : Science Magazine. 315, 5809, p. 244-247

Research output: Contribution to journal/periodicalArticleScientificpeer-review

The Intestinal Wnt/TCF Signature

Flier, L. G. V. D., Sabates-Bellver, J., Oving, I., Haegebarth, A., Palo, M. D., Anti, M., Gijn, M. E. V., Suijkerbuijk, S., Wetering, M. V. D., Marra, G. & Clevers, J. C., 2007, In : Gastroenterology. 132, p. 628-632

Research output: Contribution to journal/periodicalArticleScientificpeer-review

WNT signaling in the normal intestine and colorectal cancer

Lau, W. D., Barker, N. & Clevers, J. C., 2007, In : Frontiers in Bioscience: a journal and virtual library. 12, p. 471-491

Research output: Contribution to journal/periodicalArticleScientificpeer-review

2006

Adenomatous polyposis coli-deficient zebrafish are susceptible to digestive tract neoplasia.

Haramis, A-PG., Hurlstone, A., Velden, Y. V. D., Begthel, H., Born, M. V. D., Offerhaus, G. J. A. & Clevers, J. C., 2006, In : EMBO Reports. 7, p. 444-449

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Approaches to microRNA discovery

Cuppen, E., Berezikov, E. & Plasterk, R., 2006, In : Nature Genetics. 38 Suppl, p. 2-7 6 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

AU-rich elements and alternative splicing in the beta-catenin 3'UTR can influence the human beta-catenin mRNA stability.

Thiele, A., Nagamine, Y., Hauschildt, S. & Clevers, J. C., 2006, In : Experimental Cell Research. 312, p. 2367-2378

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Blood Pressure in Mutant Rats Lacking the 5-Hydroxytryptamine Transporter

Homberg, J. R., Mudde, J. B., Braam, B., Ellenbroek, B. A., Cuppen, E. & Joles, J. A., 2006, In : Hypertension.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Cloning and expression of new microRNAs from zebrafish

Kloosterman, W. P., Steiner, F. A., Berezikov, E., de Bruijn, E. S., van de Belt, J., Verheul, M., Cuppen, E. & Plasterk, R., 2006, In : Nucleic Acids Research. 34, 9, p. 2558-2569

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

Colon cancer--understanding how NSAIDs work.

Clevers, J. C., 2006, In : The New England Journal of Medicine. 354, p. 761-763

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Couples' attitudes, childbirth and the division of labour

Jansen, M. & Liefbroer, A. C., 2006, In : Journal of Family Issues. 27, 11, p. 1487-1511

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Differences in vertebrate microRNA expression

Ason, B., Darnell, D. K., Wittbrodt, B., Berezikov, E., Kloosterman, W. P., Wittbrodt, J., Antin, P. B. & Plasterk, R. H. A., 26 Sep 2006, In : Proceedings of the National Academy of Sciences of the United States of America. 103, 39, p. 14385-14389

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

Diversity of microRNAs in human and chimpanzee brain

Cuppen, E., 2006, In : Nature Genetics.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Dysfunctional AMPK activity, signalling through mTOR and survival in response to energetic stress in LKB1-deficient lung cancer.

Carretero, J., Medina, P. P., Blanco, R., Smit, L., Tang, M., Roncador, G., Maestre, L., Conde, E., Lopez-Rios, F., Clevers, J. C. & Sanchez-Cespedes, M., 2006, In : Oncogene advance online publication.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

EphB/EphrinB receptors and Wnt signaling in colorectal cancer.

Clevers, J. C. & Batlle, E., 2006, In : Cancer Research. 66, p. 2-5

Research output: Contribution to journal/periodicalArticleScientificpeer-review

From gut homeostasis to cancer.

Radtke, F., Clevers, J. C. & Riccio, O., 2006, In : Current Molecular Medicine. 6, p. 275-289

Research output: Contribution to journal/periodicalArticleScientificpeer-review