Research output per year
Research output per year
- 100 - 131 out of 131 results
Search results
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2014
Inter- and intratumoral heterogeneity of BCL2 correlates with IgH expression and prognosis in follicular lymphoma
Barreca, A., Martinengo, C., Annaratone, L., Righi, L., Chiappella, A., Ladetto, M., Demurtas, A., Chiusa, L., Stacchini, A., Crosetto, N., van Oudenaarden, A. & Chiarle, R., 2014, In: Blood Cancer Journal. 4, p. e249Research output: Contribution to journal/periodical › Article › Scientific › peer-review
14 Citations (Scopus) -
Transcriptional profiling of cells sorted by RNA abundance
Klemm, S., Semrau, S., Wiebrands, K., Mooijman, D., Faddah, D. A., Jaenisch, R. & van Oudenaarden, A., May 2014, In: Nature Methods. 11, 5, p. 549-51 3 p.Research output: Contribution to journal/periodical › Article › Scientific › peer-review
27 Citations (Scopus) -
Transformation of intestinal stem cells into gastric stem cells on loss of transcription factor Cdx2
Simmini, S., Bialecka, M., Huch, M., Kester, L., van de Wetering, M., Sato, T., Beck, F., van Oudenaarden, A., Clevers, H. & Deschamps, J., 2014, In: Nature Communications. 5, p. 5728Research output: Contribution to journal/periodical › Article › Scientific › peer-review
85 Citations (Scopus) -
Validation of noise models for single-cell transcriptomics
Grün, D., Kester, L. & van Oudenaarden, A., Jun 2014, In: Nature Methods. 11, 6, p. 637-40 4 p.Research output: Contribution to journal/periodical › Article › Scientific › peer-review
494 Citations (Scopus) -
2013
Allele-specific detection of single mRNA molecules in situ
Hansen, C. H. & van Oudenaarden, A., 2013, In: Nature Methods. 10, 9, p. 869-871Research output: Contribution to journal/periodical › Article › Scientific › peer-review
55 Citations (Scopus) -
A versatile genome-scale PCR-based pipeline for high-definition DNA FISH
Bienko, M., Crosetto, N., Teytelman, L., Klemm, S., Itzkovitz, S. & van Oudenaarden, A., 2013, In: Nature Methods. 10, 2, p. 122-124Research output: Contribution to journal/periodical › Article › Scientific › peer-review
51 Citations (Scopus) -
Dampening of expression oscillations by synchronous regulation of a microRNA and its target
Kim, D., Grun, D. & van Oudenaarden, A., 2013, In: Nature Genetics. 45, 11, p. 1337-1344Research output: Contribution to journal/periodical › Article › Scientific › peer-review
77 Citations (Scopus) -
Deconvolving the roles of Wnt ligands and receptors in sensing and amplification
Tan, R. Z., Ji, N., Mentink, R. A., Korswagen, H. C. & van Oudenaarden, A., 2013, In: Molecular Systems Biology. 9, p. 631Research output: Contribution to journal/periodical › Article › Scientific › peer-review
4 Citations (Scopus) -
Feedback control of gene expression variability in the Caenorhabditis elegans Wnt pathway
Ji, N., Middelkoop, T. C., Mentink, R. A., Betist, M. C., Tonegawa, S., Mooijman, D., Korswagen, H. C. & van Oudenaarden, A., 2013, In: Cell. 155, 4, p. 869-880Research output: Contribution to journal/periodical › Article › Scientific › peer-review
65 Citations (Scopus) -
Highly expressed loci are vulnerable to misleading ChIP localization of multiple unrelated proteins
Teytelman, L., Thurtle, D. M., Rine, J. & van Oudenaarden, A., 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 46, p. 18602-18607Research output: Contribution to journal/periodical › Article › Scientific › peer-review
294 Citations (Scopus) -
Single-molecule mRNA detection and counting in mammalian tissue
Lyubimova, A., Itzkovitz, S., Junker, J. P., Fan, Z. P., Wu, X. & van Oudenaarden, A., 2013, In: Nature Protocols. 8, 9, p. 1743-1758Research output: Contribution to journal/periodical › Article › Scientific › peer-review
148 Citations (Scopus) -
Stochastic cytokine expression induces mixed T helper cell States
Fang, M., Xie, H., Dougan, S. K., Ploegh, H. & van Oudenaarden, A., 2013, In: PLoS Biology. 11, 7, p. 1001618Research output: Contribution to journal/periodical › Article › Scientific › peer-review
47 Citations (Scopus) -
Systematic identification of signal-activated stochastic gene regulation
Neuert, G., Munsky, B., Tan, R. Z., Teytelman, L., Khammash, M. & van Oudenaarden, A., 2013, In: Science Magazine. 339, 6119, p. 584-587Research output: Contribution to journal/periodical › Article › Scientific › peer-review
206 Citations (Scopus) -
2012
A conserved cell growth cycle can account for the environmental stress responses of divergent eukaryotes
Slavov, N., Airoldi, E. M., van Oudenaarden, A. & Botstein, D., 2012, In: Molecular Biology of the Cell. 23, 10, p. 1986-1997Research output: Contribution to journal/periodical › Article › Scientific › peer-review
34 Citations (Scopus) -
A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal
van Es, J. H., Haegebarth, A., Kujala, P., Itzkovitz, S., Koo, B. K., Boj, S. F., Korving, J., van den Born, M., van Oudenaarden, A., Robine, S. & Clevers, H., 2012, In: Molecular and Cellular Biology. 32, 10, p. 1918-1927Research output: Contribution to journal/periodical › Article › Scientific › peer-review
213 Citations (Scopus) -
Dll1+ secretory progenitor cells revert to stem cells upon crypt damage
van Es, J. H., Sato, T., van de Wetering, M., Lyubimova, A., Nee, A. N., Gregorieff, A., Sasaki, N., Zeinstra, L., van den Born, M., Korving, J., Martens, A. C., Barker, N., van Oudenaarden, A. & Clevers, H., 2012, In: Nature Cell Biology. 14, 10, p. 1099-1104Research output: Contribution to journal/periodical › Article › Scientific › peer-review
617 Citations (Scopus) -
How to regulate a gene: to repress or to activate?
Slavov, N. & van Oudenaarden, A., 2012, In: Molecular Cell. 46, 5, p. 551-552Research output: Contribution to journal/periodical › Article › Scientific › peer-review
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Identifying the stem cell of the intestinal crypt: strategies and pitfalls
Barker, N., van Oudenaarden, A. & Clevers, H., 2012, In: Cell Stem Cell. 11, 4, p. 452-460Research output: Contribution to journal/periodical › Article › Scientific › peer-review
265 Citations (Scopus) -
In de VS begin je met veel geld en een leeg lab
van Oudenaarden, A., 03 Nov 2012, In: NRC Handelsblad. Wetenschapsbijlage, p. 9-9 1 p.Research output: Contribution to journal/periodical › Article › Popularizing
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Neural-specific Sox2 input and differential Gli-binding affinity provide context and positional information in Shh-directed neural patterning
Peterson, K. A., Nishi, Y., Ma, W., Vedenko, A., Shokri, L., Zhang, X., McFarlane, M., Baizabal, J. M., Junker, J. P., van Oudenaarden, A., Mikkelsen, T., Bernstein, B. E., Bailey, T. L., Bulyk, M. L., Wong, W. H. & McMahon, A. P., 2012, In: Genes & Development. 26, 24, p. 2802-2816Research output: Contribution to journal/periodical › Article › Scientific › peer-review
141 Citations (Scopus) -
Optimality in the development of intestinal crypts
Itzkovitz, S., Blat, I. C., Jacks, T., Clevers, H. & van Oudenaarden, A., 2012, In: Cell. 148, 3, p. 608-619Research output: Contribution to journal/periodical › Article › Scientific › peer-review
126 Citations (Scopus) -
Single-cell expression analyses during cellular reprogramming reveal an early stochastic and a late hierarchic phase
Buganim, Y., Faddah, D. A., Cheng, A. W., Itskovich, E., Markoulaki, S., Ganz, K., Klemm, S. L., van Oudenaarden, A. & Jaenisch, R., 2012, In: Cell. 150, 6, p. 1209-1222Research output: Contribution to journal/periodical › Article › Scientific › peer-review
671 Citations (Scopus) -
Single molecule fluorescent in situ hybridization (smFISH) of C. elegans worms and embryos
Ji, N. & van Oudenaarden, A., 2012, In: WormBook. p. 1-16Research output: Contribution to journal/periodical › Article › Scientific › peer-review
72 Citations (Scopus) -
Single-molecule transcript counting of stem-cell markers in the mouse intestine
Itzkovitz, S., Lyubimova, A., Blat, I. C., Maynard, M., van Es, J. H., Lees, J., Jacks, T., Clevers, H. & van Oudenaarden, A., 2012, In: Nature Cell Biology. 14, 1, p. 106-114Research output: Contribution to journal/periodical › Article › Scientific › peer-review
276 Citations (Scopus) -
The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers
Munoz, J., Stange, D. E., Schepers, A. G., van de Wetering, M., Koo, B. K., Itzkovitz, S., Volckmann, R., Kung, K. S., Koster, J., Radulescu, S., Myant, K., Versteeg, R., Sansom, O. J., van Es, J. H., Barker, N., van Oudenaarden, A., Mohammed, S., Heck, A. J. R. & Clevers, H., 2012, In: EMBO Journal. 31, 14, p. 3079-3091Research output: Contribution to journal/periodical › Article › Scientific › peer-review
597 Citations (Scopus) -
The thrombospondin repeat containing protein MIG-21 controls a left-right asymmetric Wnt signaling response in migrating C. elegans neuroblasts
Middelkoop, T. C., Williams, L., Yang, P. T., Luchtenberg, J., Betist, M. C., Ji, N., van Oudenaarden, A., Kenyon, C. & Korswagen, H. C., 2012, In: Developmental Biology. 361, 2, p. 338-348Research output: Contribution to journal/periodical › Article › Scientific › peer-review
24 Citations (Scopus) -
Transcription of two long noncoding RNAs mediates mating-type control of gametogenesis in budding yeast
van Werven, F. J., Neuert, G., Hendrick, N., Lardenois, A., Buratowski, S., van Oudenaarden, A., Primig, M. & Amon, A., 2012, In: Cell. 150, 6, p. 1170-1181Research output: Contribution to journal/periodical › Article › Scientific › peer-review
212 Citations (Scopus) -
UNC-4 antagonizes Wnt signaling to regulate synaptic choice in the C. elegans motor circuit
Schneider, J., Skelton, R. L., Von Stetina, S. E., Middelkoop, T. C., van Oudenaarden, A., Korswagen, H. C. & Miller, D. M., 2012, In: Development. 139, 12, p. 2234-2245Research output: Contribution to journal/periodical › Article › Scientific › peer-review
15 Citations (Scopus) -
Using gene expression noise to understand gene regulation
Munsky, B., Neuert, G. & van Oudenaarden, A., 2012, In: Science Magazine. 336, 6078, p. 183-187Research output: Contribution to journal/periodical › Article › Scientific › peer-review
564 Citations (Scopus) -
When noisy neighbors are a blessing: analysis of gene expression noise identifies coregulated genes
Junker, J. P. & van Oudenaarden, A., 2012, In: Molecular Cell. 45, 4, p. 437-438Research output: Contribution to journal/periodical › Article › Scientific › peer-review
3 Citations (Scopus) -
2011
Neuroblast migration along the anteroposterior axis of C. elegans is controlled by opposing gradients of Wnts and a secreted Frizzled-related protein
Harterink, M., Kim, D. H., Middelkoop, T. C., Doan, T. D., van Oudenaarden, A. & Korswagen, H. C., 2011, In: Development. 138, 14, p. 2915-2924Research output: Contribution to journal/periodical › Article › Scientific › peer-review
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