Research output per year
Research output per year
- 1 - 50 out of 711 results
Search results
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2025
Histamine 2 receptor: Emerging target for the treatment of attention-deficit/hyperactivity disorder
Shan, L. & Swaab, D. F., 18 Mar 2025, In: Cell reports. Medicine. 6, 3, p. 102023Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile21 Downloads (Pure) -
Increased oxytocin/vasopressin ratio in bipolar disorder in a cohort of human postmortem adults
Tan, H., Hu, Y.-T., Goudswaard, A., Li, Y.-J., Balesar, R., Swaab, D. & Bao, A.-M., 07 Apr 2025, In: Neurobiology of Disease. 209, p. 106904Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile10 Downloads (Pure) -
Neuroglia in suicide
Zhang, L. & Swaab, D. F., Feb 2025, In: Handbook of Clinical Neurology. 210, p. 371-379 9 p.Research output: Contribution to journal/periodical › Article › Scientific › peer-review
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Resilience to Alzheimer's disease associates with alterations in perineuronal nets
de Vries, L. E., Bahnerth, A., Swaab, D. F., Verhaagen, J. & Carulli, D., 01 Jan 2025, In: Alzheimer's & dementia : the journal of the Alzheimer's Association. 21, e14504.Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile2 Citations (Scopus)46 Downloads (Pure) -
Selective changes in vasopressin neurons and astrocytes in the suprachiasmatic nucleus of Prader-Willi syndrome subjects
Correa-da-Silva, F., Berkhout, J. B., Schouten, P., Sinnema, M., Stumpel, C. T. R. M., Curfs, L. M. G., Höybye, C., Mahfouz, A., Meijer, O. C., Pereira, A. M., Fliers, E., Swaab, D. F., Kalsbeek, A. & Yi, C.-X., 08 Mar 2025, In: Journal of Neuroendocrinology. 37, p. e70015Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile41 Downloads (Pure) -
Sleep-wake modulation and pathogenesis of Alzheimer disease: Suggestions for postponement and treatment
Liu, Y.-J., Swaab, D. F. & Zhou, J.-N., Jan 2025, In: Handbook of Clinical Neurology. 206, p. 211-229 19 p.Research output: Contribution to journal/periodical › Article › Scientific › peer-review
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2024
Gene-expression profiling of individuals resilient to Alzheimer's disease reveals higher expression of genes related to metallothionein and mitochondrial processes and no changes in the unfolded protein response
de Vries, L. E., Jongejan, A., Monteiro Fortes, J., Balesar, R., Rozemuller, A. J. M., Moerland, P. D., Huitinga, I., Swaab, D. F. & Verhaagen, J., 25 Apr 2024, In: Acta neuropathologica communications. 12, 1, p. 68Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile6 Citations (Scopus)84 Downloads (Pure) -
Microglial phagolysosome dysfunction and altered neural communication amplify phenotypic severity in Prader-Willi Syndrome with larger deletion
Correa-da-Silva, F., Carter, J., Wang, X.-Y., Sun, R., Pathak, E., Kuhn, J. M. M., Schriever, S. C., Maya-Monteiro, C. M., Jiao, H., Kalsbeek, M. J., Moraes-Vieira, P. M. M., Gille, J. J. P., Sinnema, M., Stumpel, C. T. R. M., Curfs, L. M. G., Stenvers, D. J., Pfluger, P. T., Lutter, D., Pereira, A. M. & Kalsbeek, A. & 5 others, , 31 Mar 2024, In: Acta Neuropathologica. 147, 1, p. 64Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile6 Citations (Scopus)78 Downloads (Pure) -
Progesterone receptor distribution in the human hypothalamus and its association with suicide
Zhang, L., Verwer, R. W. H., van Heerikhuize, J., Lucassen, P. J., Nathanielsz, P. W., Hol, E. M., Aronica, E., Dhillo, W. S., Meynen, G. & Swaab, D. F., 23 Jan 2024, In: Acta neuropathologica communications. 12, 1, p. 16Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile2 Citations (Scopus)85 Downloads (Pure) -
Reporting Psychiatric Disease Characteristics in Post-Mortem- and Biological Research
Scheepstra, K., Mizee, M., Wever, D., Hsiao, C.-C., Zhang, L., Swaab, D., Hamann, J. & Huitinga, I., May 2024, In: Neuroscience Insights. 19, p. 26331055241252632Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile1 Citation (Scopus)56 Downloads (Pure) -
Sex differences in bipolar disorder: the dorsolateral prefrontal cortex as an etiopathogenic region
Zhang, L. & Swaab, D. F., 02 Jan 2024, In: Frontiers in Neuroendocrinology. 72, p. 101115Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile7 Citations (Scopus)139 Downloads (Pure) -
The concept of resilience to Alzheimer's Disease: current definitions and cellular and molecular mechanisms
de Vries, L. E., Huitinga, I., Kessels, H. W., Swaab, D. F. & Verhaagen, J., 08 Apr 2024, In: Molecular Neurodegeneration. 19, 1, p. 33Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile22 Citations (Scopus)109 Downloads (Pure) -
2023
Activated wake systems in narcolepsy type 1
Shan, L., Linssen, S., Harteman, Z., den Dekker, F., Shuker, L., Balesar, R., Breesuwsma, N., Anink, J., Zhou, J., Lammers, G. J., Swaab, D. F. & Fronczek, R., 03 Jul 2023, In: Annals of Neurology. 94, p. 762-771Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile7 Citations (Scopus)51 Downloads (Pure) -
Alterations in pituitary adenylate cyclase-activating polypeptide in major depressive disorder, bipolar disorder, and comorbid depression in Alzheimer's disease in the human hypothalamus and prefrontal cortex
Slabe, Z., Balesar, R. A., Verwer, R. W. H., Van Heerikhuize, J. J., Pechler, G. A., Zorović, M., Hoogendijk, W. J. G. & Swaab, D. F., 25 May 2023, In: Psychological Medicine. 53, p. 7537-7549 13 p.Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile10 Citations (Scopus)69 Downloads (Pure) -
Disease stage-dependent changes in brain levels and neuroprotective effects of neuroactive steroids in Parkinson's disease
Luchetti, S., Liere, P., Pianos, A., Verwer, R. W. H., Sluiter, A., Huitinga, I., Schumacher, M., Swaab, D. F. & Mason, M. R. J., 29 May 2023, In: Neurobiology of Disease. 183, 106169.Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile15 Citations (Scopus)89 Downloads (Pure) -
Increased pituitary adenylate cyclase-activating peptide genes expression in the prefrontal cortex in schizophrenia in relation to suicide
Slabe, Z., Balesar, R. A., Verwer, R. W. H., Drevenšek, G. & Swaab, D. F., Nov 2023, In: Frontiers in Molecular Neuroscience. 16, 1277958.Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open Access4 Citations (Scopus) -
Increased pituitary adenylate cyclase-activating polypeptide in the central bed nucleus of the stria terminalis in mood disorders in men
Slabe, Z., Pechler, G. A., van Heerikhuize, J., Samuels, B. A., Živin, M., Zorović, M. & Swaab, D. F., 06 Jun 2023, In: Neurobiology of Disease. 183, p. 106191Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile6 Citations (Scopus)64 Downloads (Pure) -
Reduction of oxytocin-containing neurons and enhanced glymphatic activity in the hypothalamic paraventricular nucleus of patients with type 2 diabetes mellitus
Correa-da-Silva, F., Kalsbeek, M. J., Gadella, F. S., Oppersma, J., Jiang, W., Wolff, S. E. C., Korpel, N. L., Swaab, D. F., Fliers, E., Kalsbeek, A. & Yi, C.-X., 03 Jul 2023, In: Acta neuropathologica communications. 11, 1, p. 107Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile9 Citations (Scopus)60 Downloads (Pure) -
Sex differences in hippocampal β-amyloid accumulation in the triple-transgenic mouse model of Alzheimer's disease and the potential role of local estrogens
Hu, Y.-T., Chen, X.-L., Zhang, Y.-N., McGurran, H., Stormmesand, J., Breeuwsma, N., Sluiter, A., Zhao, J., Swaab, D. & Bao, A.-M., 19 Mar 2023, In: Frontiers in Neuroscience. 17, p. 1117584Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile11 Citations (Scopus)590 Downloads (Pure) -
Sexually dimorphic age-related molecular differences in the entorhinal cortex of cognitively intact elderly: Relation to early Alzheimer's changes
Chen, X.-L., Fortes, J. M., Hu, Y.-T., van Iersel, J., He, K.-N., van Heerikhuize, J., Balesar, R., Swaab, D. & Bao, A.-M., 24 Mar 2023, In: Alzheimer's & dementia : the journal of the Alzheimer's Association. 19, p. 3848-3857Research output: Contribution to journal/periodical › Article › Scientific › peer-review
6 Citations (Scopus) -
SIRT1 in the BNST modulates chronic stress-induced anxiety of male mice via FKBP5 and corticotropin-releasing factor signaling
Hu, P., Wang, Y., Qi, X.-H., Shan, Q.-H., Huang, Z.-H., Chen, P., Ma, X., Yang, Y.-P., Swaab, D. F., Samuels, B. A., Zhang, Z. & Zhou, J.-N., 28 Dec 2023, In: Molecular Psychiatry. 28, p. 5101-5117Research output: Contribution to journal/periodical › Article › Scientific › peer-review
17 Citations (Scopus) -
2022
A unified 3D map of microscopic architecture and MRI of the human brain
Alkemade, A., Bazin, P.-L., Balesar, R., Pine, K., Kirilina, E., Möller, H. E., Trampel, R., Kros, J. M., Keuken, M. C., Bleys, R. L. A. W., Swaab, D. F., Herrler, A., Weiskopf, N. & Forstmann, B. U., 29 Apr 2022, In: Science advances. 8, 17, p. eabj7892Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile39 Citations (Scopus)166 Downloads (Pure) -
Changes in histaminergic system in neuropsychiatric disorders and the potential treatment consequences
Shan, L. & Swaab, D. F., 2022, In: Current neuropharmacology. 20, p. 403-411Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile9 Citations (Scopus)206 Downloads (Pure) -
Different oxytocin and corticotropin-releasing hormone system changes in bipolar disorder and major depressive disorder patients
Guo, L., Qi, Y.-J., Tan, H., Dai, D., Balesar, R., Sluiter, A., van Heerikhuize, J., Hu, S.-H., Swaab, D. F. & Bao, A.-M., 16 Sept 2022, In: EBioMedicine. 84, p. 104266Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile12 Citations (Scopus)85 Downloads (Pure) -
Distinct proteomic profiles in prefrontal subareas of elderly major depressive disorder and bipolar disorder patients
Qi, Y.-J., Lu, Y.-R., Shi, L.-G., Demmers, J. A. A., Bezstarosti, K., Rijkers, E., Balesar, R., Swaab, D. & Bao, A.-M., 11 Jul 2022, In: Translational Psychiatry. 12, 1, p. 275Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile11 Citations (Scopus)69 Downloads (Pure) -
Hippocampal neuropathology in suicide: Gaps in our knowledge and opportunities for a breakthrough.
Zhang, L., Lucassen, P. J., Salta, E., Verhaert, P. D. E. M. & Swaab, D. F., Jan 2022, In: Neuroscience and Biobehavioral Reviews. 132, p. 542-552Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile13 Citations (Scopus)263 Downloads (Pure) -
Histamine-4 Receptor: Emerging Target for the Treatment of Neurological Diseases
Shan, L., Martens, G. J. M. & Swaab, D. F., 2022, In: Current Topics in Behavioral Neurosciences. 59, p. 131-145Research output: Contribution to journal/periodical › Article › Scientific › peer-review
5 Citations (Scopus) -
Reduced numbers of corticotropin-releasing hormone neurons in narcolepsy type 1
Shan, L., Balesar, R., Swaab, D. F., Lammers, G. J. & Fronczek, R., Jan 2022, In: Annals of Neurology. 91, p. 282-288Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile28 Citations (Scopus)225 Downloads (Pure) -
Reply to Sharifpour et al. Light response measurement of the human SCN by 7T fMRI
Meijer, J. H., de Rover, M., de Torres Gutiérrez, P., Swaab, D. F., van Osch, M. J. P. & Schoonderwoerd, R. A., 06 Dec 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 49, p. e2215410119Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile1 Citation (Scopus)23 Downloads (Pure) -
The photobiology of the human circadian clock
Schoonderwoerd, R. A., de Rover, M., Janse, J. A. M., Hirschler, L., Willemse, C. R., Scholten, L., Klop, I., van Berloo, S., van Osch, M. J. P., Swaab, D. F. & Meijer, J. H., 29 Mar 2022, In: Proceedings of the National Academy of Sciences of the United States of America. 119, 13, p. e2118803119Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile20 Citations (Scopus)52 Downloads (Pure) -
2021
Changes in glial gene expression in the prefrontal cortex in relation to major depressive disorder, suicide and psychotic features
Zhang, L., Verwer, R. W. H., Zhao, J., Huitinga, I., Lucassen, P. J. & Swaab, D. F., 01 Dec 2021, In: Journal of Affective Disorders. 295, p. 893-903 11 p.Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open Access25 Citations (Scopus) -
Changes of Hypocretin (Orexin) System in Schizophrenia: From Plasma to Brain
Lu, J., Huang, M.-L., Li, J.-H., Jin, K.-Y., Li, H.-M., Mou, T.-T., Fronczek, R., Duan, J.-F., Xu, W.-J., Swaab, D. & Bao, A.-M., May 2021, In: Schizophrenia bulletin. 47, p. 1310-1319Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile17 Citations (Scopus)355 Downloads (Pure) -
Discovery of new genetic loci for male sexual orientation in Han population
Hu, S.-H., Li, H.-M., Yu, H., Liu, Y., Liu, C.-X., Zuo, X.-B., Lu, J., Jiang, J.-J., Xi, C.-X., Huang, B.-C., Xu, H.-J., Hu, J.-B., Lai, J.-B., Huang, M.-L., Liu, J.-N., Xu, D.-G., Guo, X.-C., Wu, W., Wu, X. & Jiang, L. & 33 others, , Oct 2021, In: Cell discovery. 7, 1, p. 103Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile8 Citations (Scopus)143 Downloads (Pure) -
Estrogen receptor α splice variant TADDI in the human supraoptic nucleus: an effect on neuronal size and changes in pneumonia
Ishunina, T. A. & Swaab, D. F., 04 May 2021, In: Neuro endocrinology letters. 42, 2, p. 128-132 5 p.Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile78 Downloads (Pure) -
Histamine-4 receptor antagonist ameliorates Parkinson-like pathology in the striatum
Fang, Q., Xicoy, H., Shen, J., Luchetti, S., Dai, D., Zhou, P., Qi, X.-R., Martens, G. J. M., Huitinga, I., Swaab, D. F., Liu, C. & Shan, L., 2021, In: Brain, Behavior, and Immunity. 92, p. 127-138Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile29 Citations (Scopus)315 Downloads (Pure) -
Histamine H1 receptor deletion in cholinergic neurons induces sensorimotor gating ability deficit and social impairments in mice
Cheng, L., Xu, C., Wang, L., An, D., Jiang, L., Zheng, Y., Xu, Y., Wang, Y., Wang, Y., Zhang, K., Wang, X., Zhang, X., Bao, A., Zhou, Y., Yang, J., Duan, S., Swaab, D. F., Hu, W. & Chen, Z., Jan 2021, In: Nature Communications. 12, 1, p. 1142Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile30 Citations (Scopus)109 Downloads (Pure) -
History of hypothalamic research: "The spring of primitive existence"
Kreier, F. & Swaab, D. F., 2021, In: Handbook of Clinical Neurology. 179, p. 7-43 37 p.Research output: Contribution to journal/periodical › Article › Scientific › peer-review
7 Citations (Scopus) -
Hypothalamic neuropeptides and neurocircuitries in Prader Willi syndrome
Correa-da-Silva, F., Fliers, E., Swaab, D. F. & Yi, C.-X., May 2021, In: Journal of Neuroendocrinology. 33, p. e12994Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile26 Citations (Scopus)160 Downloads (Pure) -
Introduction: The anterior hypothalamus
Swaab, D. F., Buijs, R. M., Kreier, F., Lucassen, P. J. & Salehi, A., 2021, In: Handbook of Clinical Neurology. 179, p. 3-5 3 p.Research output: Contribution to journal/periodical › Article › Scientific › peer-review
3 Citations (Scopus) -
Introduction: The middle and posterior hypothalamus
Swaab, D. F., Kreier, F., Lucassen, P. J., Salehi, A. & Buijs, R. M., 2021, In: Handbook of Clinical Neurology. 180, p. 1-4 4 p.Research output: Contribution to journal/periodical › Article › Scientific › peer-review
4 Citations (Scopus) -
Introduction The human hypothalamus and neuroendocrine disorders
Swaab, D. F., Buijs, R. M., Lucassen, P. J., Salehi, A. & Kreier, F., 2021, In: Handbook of Clinical Neurology. 181, p. 1-5 5 p.Research output: Contribution to journal/periodical › Article › Scientific › peer-review
1 Citation (Scopus) -
Introduction The human hypothalamus and neuropsychiatric disorders
Swaab, D. F., Buijs, R. M., Kreier, F., Lucassen, P. J. & Salehi, A., 2021, In: Handbook of Clinical Neurology. 182, p. 1-5 5 p.Research output: Contribution to journal/periodical › Article › Scientific › peer-review
3 Citations (Scopus) -
Matching of the postmortem hypothalamus from patients and controls
Swaab, D. F. & Bao, A.-M., 2021, In: Handbook of Clinical Neurology. 179, p. 141-156 16 p.Research output: Contribution to journal/periodical › Article › Scientific › peer-review
6 Citations (Scopus) -
Preface Handbook of Clinical Neurology volume179
Swaab, D. F., Kreier, F., Lucassen, P. J., Salehi, A. & Buijs, R. M., 2021, In: Handbook of Clinical Neurology. 179, p. ix-xiResearch output: Contribution to journal/periodical › Article › Scientific › peer-review
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Preface Handbook of Clinical Neurology volume 182
Swaab, D. F., Buijs, R. M., Kreier, F., Lucassen, P. J. & Salehi, A., 2021, In: Handbook of Clinical Neurology. 182, p. ix-xiResearch output: Contribution to journal/periodical › Article › Scientific › peer-review
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PSD-93 up-regulates the synaptic activity of corticotropin-releasing hormone neurons in the paraventricular nucleus in depression
Qin, X.-Y., Shan, Q.-H., Fang, H., Wang, Y., Chen, P., Xiong, Z.-Q., Swaab, D. F. & Zhou, J.-N., Sept 2021, In: Acta Neuropathologica. 142, p. 1045-1064Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile26 Citations (Scopus)77 Downloads (Pure) -
Sex differences in the neuropathological hallmarks of Alzheimer's disease: focus on cognitively intact elderly individuals
Hu, Y.-T., Boonstra, J., McGurran, H., Stormmesand, J., Sluiter, A., Balesar, R., Verwer, R., Swaab, D. & Bao, A.-M., 2021, In: Neuropathology and Applied Neurobiology. 47, p. 958-966Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile19 Citations (Scopus)174 Downloads (Pure) -
Sexual differentiation of the human hypothalamus: Relationship to gender identity and sexual orientation
Swaab, D. F., Wolff, S. E. C. & Bao, A.-M., 2021, In: Handbook of Clinical Neurology. 181, p. 427-443 17 p.Research output: Contribution to journal/periodical › Article › Scientific › peer-review
20 Citations (Scopus) -
Sexual orientation, neuropsychiatric disorders and the neurotransmitters involved
Li, H., Fernández-Guasti, A., Xu, Y. & Swaab, D., 28 Sept 2021, In: Neuroscience and Biobehavioral Reviews. 131, p. 479-488Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile1 Citation (Scopus)317 Downloads (Pure) -
The Spanish Composer Manuel de Falla and His Eyes: The Musical Brain
Garcia-Falgueras, A. & Swaab, D. F., 2021, In: Neuroscience Insights. 16, p. 1-10Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile3 Citations (Scopus)99 Downloads (Pure)