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Personal profile


Hans Clevers obtained his MD degree in 1984 and his PhD degree in 1985 from the University Utrecht, the Netherlands. His postdoctoral work (1986-1989) was done with Cox Terhorst at the Dana-Farber Cancer Institute of the Harvard University, Boston, USA.

From 1991-2002 Hans Clevers was Professor in Immunology at the University Utrecht and, since 2002, Professor in Molecular Genetics. From 2002-2012 he was director of the Hubrecht Institute in Utrecht . From 2012-2015 he was President of the Royal Netherlands Academy of Arts and Sciences (KNAW). Hans is director research of the Princess Maxima Center for Pediatric Oncology since June 1, 2015.

Hans Clevers has been a member of the Royal Netherlands Academy of Arts and Sciences since 2000, a member of the American Academy of Arts and Sciences since 2012 and a member of the National Academy of Sciences of the USA  since 2014. He is the recipient of several awards, including the Dutch Spinoza Award in 2001, the Swiss Louis Jeantet Prize in 2004, the Memorial Sloan-Kettering Katharine Berkan Judd Award in 2005, the Israeli Rabbi Shai Shacknai Memorial Prize in 2006, the Dutch Josephine Nefkens Prize for Cancer Research and the German Meyenburg Cancer Research Award in 2008, the Dutch Cancer Society Award in 2009, the United European Gastroenterology Federation (UEGF) Research Prize in 2010, the German Ernst Jung-Preis für Medizin in 2011, the French Association pour la Recherche sur le Cancer (ARC) Léopold Griffuel Prize and the Heineken Prize in 2012 and the Breakthrough Prize in Life Sciences in 2013. He obtained an ERC Advanced Investigator grant in 2008. He is Chevalier de la Legion d’Honneur since 2005 and Knight in the Order of the Netherlands Lion since 2012.


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  • An organoid biobank for childhood kidney cancers that captures disease and tissue heterogeneity

    Calandrini, C., Schutgens, F., Oka, R., Margaritis, T., Candelli, T., Mathijsen, L., Ammerlaan, C., van Ineveld, R. L., Derakhshan, S., de Haan, S., Dolman, E., Lijnzaad, P., Custers, L., Begthel, H., Kerstens, H. H. D., Visser, L. L., Rookmaaker, M., Verhaar, M., Tytgat, G. A. M., Kemmeren, P. & 11 others, de Krijger, R. R., Al-Saadi, R., Pritchard-Jones, K., Kool, M., Rios, A. C., van den Heuvel-Eibrink, M. M., Molenaar, J. J., van Boxtel, R., Holstege, F. C. P., Clevers, H. & Drost, J., 11 Mar 2020, In : Nature Communications. 11, 1, p. 1310

    Research output: Contribution to journal/periodicalArticleScientificpeer-review

    Open Access
  • Fast and efficient generation of knock-in human organoids using homology-independent CRISPR-Cas9 precision genome editing

    Artegiani, B., Hendriks, D., Beumer, J., Kok, R., Zheng, X., Joore, I., Chuva de Sousa Lopes, S., van Zon, J., Tans, S. & Clevers, H., Mar 2020, In : Nature Cell Biology. 22, 3, p. 321-331 11 p.

    Research output: Contribution to journal/periodicalArticleScientificpeer-review

  • Genome-Scale CRISPR Screening in Human Intestinal Organoids Identifies Drivers of TGF-β Resistance

    Ringel, T., Frey, N., Ringnalda, F., Janjuha, S., Cherkaoui, S., Butz, S., Srivatsa, S., Pirkl, M., Russo, G., Villiger, L., Rogler, G., Clevers, H., Beerenwinkel, N., Zamboni, N., Baubec, T. & Schwank, G., 05 Mar 2020, In : Cell Stem Cell. 26, 3, p. 431-440.e8

    Research output: Contribution to journal/periodicalArticleScientificpeer-review

  • How the COVID-19 pandemic highlights the necessity of animal research

    Genzel, L., Adan, R., Berns, A., van den Beucken, J., Blokland, A., Boddeke, E. H. W. G. M., Bogers, W. M., Bontrop, R., Bulthuis, R., Bousema, T., Clevers, H., Coenen, T. C. J. J., Dam, A-M. V., Deen, P. M. T., van Dijk, K. W., Eggen, B. J. L., Elgersma, Y., Erdogan, I., Englitz, B., Fentener van Vlissingen, J. M. & 62 others, la Fleur, S., Fouchier, R., Fitzsimons, C. P., Frieling, W., Haagmans, B., Heesters, B. A., Henckens, M., Herfst, S., Hol, E., van den Hove, D., de Jonge, M. I., Jonkers, J., Joosten, L. A. B., Kalsbeek, A., Kamermans, M., Kampinga, H. H., Kas, M. J., Keijer, J., Kersten, S., Kiliaan, A. J., Kooij, T. W. A., Kooijman, S., Koopman, W. J. H., Korosi, A., Krugers, H. J., Kuiken, T., Kushner, S. A., Langermans, J. A. M., Lesscher, H., Lucassen, P. J., Lutgens, E., Netea, M. G., Noldus, L. P. J. J., van der Meer, J. W. M., Meye, F. J., Mul, J. D., van Oers, K., Olivier, J. D. A., Pasterkamp, R. J., Philippens, I. H. C. H. M., Prickaerts, J., Pullox, B., Rensen, P. C. N., van Rheenen, J., van Rij, R. P., Ritsma, L., Rockx, B. H. G., Roozendaal, B., van Schothorst, E. M., Stittelaar, K., Stockhofe, N., Swaab, D. F., de Swart, R. L., Vanderschuren, L. J. M. J., de Vries, T., de Vrij, F., van Wezel, R., Wierenga, C. J., Wiesmann, M., Willuhn, I., de Zeeuw, C. I. & Homberg, J. R., 10 Aug 2020, In : Current Biology. 30, 18, p. R1014-R1018 5 p.

    Research output: Contribution to journal/periodicalArticleScientificpeer-review

    Open Access
    19 Downloads (Pure)
  • Long-Term Expansion of Pancreatic Islet Organoids from Resident Procr+ Progenitors

    Wang, D., Wang, J., Bai, L., Pan, H., Feng, H., Clevers, H. & Zeng, Y. A., 19 Mar 2020, In : Cell. 180, 6, p. 1198-1211.e19

    Research output: Contribution to journal/periodicalArticleScientificpeer-review

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