1. 2019
  2. Oral mucosal organoids as a potential platform for personalized cancer therapy

    Driehuis, E. , Kolders, S. , Spelier, S. , Lohmussaar, K. , Willems, S. M. , Devriese, L. A. , de Bree, R. , de Ruiter, E. J. , Korving, J. , Begthel, H. , Van Es, J. H. , Geurts, V. , He, G-W. , van Jaarsveld, R. H. , Oka, R. , Muraro, M. J. , Vivie, J. , Zandvliet, M. M. J. M. , Hendrickx, A. P. A. , Iakobachvili, N. & 8 others Sridevi, P., Kranenburg, O., van Boxtel, R., Kops, G. J. P. L., Tuveson, D. A., Peters, P. J., van Oudenaarden, A. & Clevers, H. 03 May 2019 In : Cancer Discovery.

    Research output: Contribution to journal/periodicalArticleScientificpeer-review

  3. Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids

    Bolhaqueiro, A. C. F. , Ponsioen, B. , Bakker, B. , Klaasen, S. J. , Kucukkose, E. , van Jaarsveld, R. H. , Vivié, J. , Verlaan-Klink, I. , Hami, N. , Spierings, D. C. J. , Sasaki, N. , Dutta, D. , Boj, S. F. , Vries, R. G. J. , Lansdorp, P. M. , van de Wetering, M. , van Oudenaarden, A. , Clevers, H. , Kranenburg, O. , Foijer, F. & 2 others Snippert, H. J. G. & Kops, G. J. P. L. May 2019 In : Nature Genetics. 51, 5, p. 824-834 11 p.

    Research output: Contribution to journal/periodicalArticleScientificpeer-review

  4. Novel Chimeric Gene Therapy Vectors Based on Adeno-Associated Virus and Four Different Mammalian Bocaviruses

    Fakhiri, J., Schneider, M. A., Puschhof, J., Stanifer, M., Schildgen, V., Holderbach, S., Voss, Y., El Andari, J., Schildgen, O., Boulant, S., Meister, M., Clevers, H., Yan, Z., Qiu, J. & Grimm, D. 15 Mar 2019 In : Molecular therapy. Methods & clinical development. 12, p. 202-222 21 p.

    Research output: Contribution to journal/periodicalArticleScientificpeer-review

  5. Tissue clonality of dendritic cell subsets and emergency DCpoiesis revealed by multicolor fate mapping of DC progenitors

    Cabeza-Cabrerizo, M., van Blijswijk, J., Wienert, S., Heim, D., Jenkins, R. P., Chakravarty, P., Rogers, N., Frederico, B., Acton, S., Beerling, E., van Rheenen, J., Clevers, H., Schraml, B. U., Bajénoff, M., Gerner, M., Germain, R. N., Sahai, E., Klauschen, F. & Reis E Sousa, C. 01 Mar 2019 In : Science immunology. 4, 33

    Research output: Contribution to journal/periodicalArticleScientificpeer-review

  6. Tubuloids derived from human adult kidney and urine for personalized disease modeling

    Schutgens, F. , Rookmaaker, M. B. , Margaritis, T. , Rios, A. , Ammerlaan, C. , Jansen, J. , Gijzen, L. , Vormann, M. , Vonk, A. , Viveen, M. , Yengej, F. Y. , Derakhshan, S. , de Winter-de Groot, K. M. , Artegiani, B. , van Boxtel, R. , Cuppen, E. , Hendrickx, A. P. A. , van den Heuvel-Eibrink, M. M. , Heitzer, E. , Lanz, H. & 7 others Beekman, J., Murk, J-L., Masereeuw, R., Holstege, F., Drost, J., Verhaar, M. C. & Clevers, H. Mar 2019 In : Nature Biotechnology. 37, 3, p. 303-313 11 p.

    Research output: Contribution to journal/periodicalArticleScientificpeer-review

  7. Identification of Enteroendocrine Regulators by Real-Time Single-Cell Differentiation Mapping

    Gehart, H., van Es, J. H., Hamer, K., Beumer, J., Kretzschmar, K., Dekkers, J. F., Rios, A. & Clevers, H. 21 Feb 2019 In : Cell. 176, 5, p. 1158-1173.e16

    Research output: Contribution to journal/periodicalArticleScientificpeer-review

  8. An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance

    Li, N., Babaei-Jadidi, R., Lorenzi, F., Spencer-Dene, B., Clarke, P., Domingo, E., Tulchinsky, E., Vries, R. G. J., Kerr, D., Pan, Y., He, Y., Bates, D. O., Tomlinson, I., Clevers, H. & Nateri, A. S. 19 Feb 2019 In : Oncogenesis. 8, 3, p. 13

    Research output: Contribution to journal/periodicalArticleScientificpeer-review

  9. Long-term expanding human airway organoids for disease modeling

    Sachs, N. , Papaspyropoulos, A. , Zomer-van Ommen, D. D. , Heo, I. , Böttinger, L. , Klay, D. , Weeber, F. , Huelsz-Prince, G. , Iakobachvili, N. , Amatngalim, G. D. , de Ligt, J. , van Hoeck, A. , Proost, N. , Viveen, M. C. , Lyubimova, A. , Teeven, L. , Derakhshan, S. , Korving, J. , Begthel, H. , Dekkers, J. F. & 28 others Kumawat, K., Ramos, E., van Oosterhout, M. F., Offerhaus, G. J., Wiener, D. J., Olimpio, E. P., Dijkstra, K. K., Smit, E. F., van der Linden, M., Jaksani, S., van de Ven, M., Jonkers, J., Rios, A. C., Voest, E. E., van Moorsel, C. H., van der Ent, C. K., Cuppen, E., van Oudenaarden, A., Coenjaerts, F. E., Meyaard, L., Bont, L. J., Peters, P. J., Tans, S. J., van Zon, J. S., Boj, S. F., Vries, R. G., Beekman, J. M. & Clevers, H. 15 Feb 2019 In : EMBO Journal. 38, 4

    Research output: Contribution to journal/periodicalArticleScientificpeer-review

  10. Rectal Organoids Enable Personalized Treatment of Cystic Fibrosis

    Berkers, G. , van Mourik, P. , Vonk, A. M. , Kruisselbrink, E. , Dekkers, J. F. , de Winter-de Groot, K. M. , Arets, H. G. M. , Marck-van der Wilt, R. E. P. , Dijkema, J. S. , Vanderschuren, M. M. , Houwen, R. H. J. , Heijerman, H. G. M. , van de Graaf, E. A. , Elias, S. G. , Majoor, C. J. , Koppelman, G. H. , Roukema, J. , Bakker, M. , Janssens, H. M. , van der Meer, R. & 5 others Vries, R. G. J., Clevers, H. C., de Jonge, H. R., Beekman, J. M. & van der Ent, C. K. 12 Feb 2019 In : Cell Reports. 26, 7, p. 1701-1708.e3

    Research output: Contribution to journal/periodicalArticleScientificpeer-review

  11. A ZNRF3-dependent Wnt/β-catenin signaling gradient is required for adrenal homeostasis

    Basham, K. J., Rodriguez, S., Turcu, A. F., Lerario, A. M., Logan, C. Y., Rysztak, M. R., Gomez-Sanchez, C. E., Breault, D. T., Koo, B-K., Clevers, H., Nusse, R., Val, P. & Hammer, G. D. 01 Feb 2019 In : Genes & Development. 33, 3-4, p. 209-220 12 p.

    Research output: Contribution to journal/periodicalArticleScientificpeer-review

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