Hans Clevers

2022

Mycobacteria-host interactions in human bronchiolar airway organoids

Iakobachvili, N., Leon-Icaza, S. A., Knoops, K., Sachs, N., Mazères, S., Simeone, R., Peixoto, A., Bernard, C., Murris-Espin, M., Mazières, J., Cam, K., Chalut, C., Guilhot, C., López-Iglesias, C., Ravelli, R. B. G., Neyrolles, O., Meunier, E., Lugo-Villarino, G., Clevers, H., Cougoule, C., & 1 othersPeters, P. J., Mar 2022, In: Molecular Microbiology.

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Open Access

32 Citations (Scopus)

Optimized human intestinal organoid model reveals interleukin-22-dependency of paneth cell formation

He, G-W., Lin, L., DeMartino, J., Zheng, X., Staliarova, N., Dayton, T., Begthel, H., van de Wetering, W. J., Bodewes, E., van Zon, J., Tans, S., Lopez-Iglesias, C., Peters, P. J., Wu, W., Kotlarz, D., Klein, C., Margaritis, T., Holstege, F. & Clevers, H., 01 Dec 2022, In: Cell Stem Cell. 29, 12, p. 1718-1720 3 p.

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

Open Access

4 Citations (Scopus)

Organoid Studies in COVID-19 Research

Kim, J., Koo, B-K. & Clevers, H., 28 Feb 2022, In: International journal of stem cells. 15, 1, p. 3-13 11 p.

Research output: Contribution to journal/periodical › Book/Film/Article review › Scientific

Open Access

16 Citations (Scopus)

Patient-derived micro-organospheres enable clinical precision oncology

Ding, S., Hsu, C., Wang, Z., Natesh, N. R., Millen, R., Negrete, M., Giroux, N., Rivera, G. O., Dohlman, A., Bose, S., Rotstein, T., Spiller, K., Yeung, A., Sun, Z., Jiang, C., Xi, R., Wilkin, B., Randon, P. M., Williamson, I., Nelson, D. A., & 17 othersDelubac, D., Oh, S., Rupprecht, G., Isaacs, J., Jia, J., Chen, C., Shen, J. P., Kopetz, S., McCall, S., Smith, A., Gjorevski, N., Walz, A-C., Antonia, S., Marrer-Berger, E., Clevers, H., Hsu, D. & Shen, X., 02 Jun 2022, In: Cell Stem Cell. 29, 6, p. 905-917.e6

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

Open Access

66 Citations (Scopus)

Patient-Derived Organoids from Colorectal Cancer with Paired Liver Metastasis Reveal Tumor Heterogeneity and Predict Response to Chemotherapy

Mo, S., Tang, P., Luo, W., Zhang, L., Li, Y., Hu, X., Ma, X., Chen, Y., Bao, Y., He, X., Fu, G., Xu, X., Rao, X., Li, X., Guan, R., Chen, S., Deng, Y., Lv, T., Mu, P., Zheng, Q., & 12 othersWang, S., Liu, F., Li, Y., Sheng, W., Huang, D., Hu, C., Gao, J., Zhang, Z., Cai, S., Clevers, H., Peng, J. & Hua, G., Nov 2022, In: Advanced Science. 9, 31, p. e2204097

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

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60 Citations (Scopus)

Rapid tissue prototyping with micro-organospheres

Wang, Z., Boretto, M., Millen, R., Natesh, N., Reckzeh, E. S., Hsu, C., Negrete, M., Yao, H., Quayle, W., Heaton, B. E., Harding, A. T., Bose, S., Driehuis, E., Beumer, J., Rivera, G. O., van Ineveld, R. L., Gex, D., DeVilla, J., Wang, D., Puschhof, J., & 18 othersGeurts, M. H., Yeung, A., Hamele, C., Smith, A., Bankaitis, E., Xiang, K., Ding, S., Nelson, D., Delubac, D., Rios, A., Abi-Hachem, R., Jang, D., Goldstein, B. J., Glass, C., Heaton, N. S., Hsu, D., Clevers, H. & Shen, X., 13 Sept 2022, In: Stem Cell Reports. 17, 9, p. 1959-1975 17 p.

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Open Access

12 Citations (Scopus)

Regulation of Solute Carriers OCT2 and OAT1/3 in the Kidney: A Phylogenetic, Ontogenetic and Cell Dynamic Perspective

Pou Casellas, C., Jansen, K., Rookmaaker, M. B., Clevers, H., Verhaar, M. C. & Masereeuw, R., Apr 2022, In: Physiological Reviews.

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16 Citations (Scopus)

Rewiring glucose metabolism improves 5-FU efficacy in p53-deficient/KRASG12D glycolytic colorectal tumors

Ludikhuize, M. C., Gevers, S., Nguyen, N. T. B., Meerlo, M., Roudbari, S. K. S., Gulersonmez, M. C., Stigter, E. C. A., Drost, J., Clevers, H., Burgering, B. M. T. & Rodríguez Colman, M. J., 31 Oct 2022, In: Communications Biology. 5, 1, p. 1159

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6 Citations (Scopus)

RNF43/ZNRF3 negatively regulates taste tissue homeostasis and positively regulates dorsal lingual epithelial tissue homeostasis

Lu, C., Lin, X., Yamashita, J., Xi, R., Zhou, M., Zhang, Y. V., Wang, H., Margolskee, R. F., Koo, B-K., Clevers, H., Matsumoto, I. & Jiang, P., 08 Feb 2022, In: Stem Cell Reports. 17, 2, p. 369-383 15 p.

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

Open Access

9 Citations (Scopus)

The Wnt Pathway: From Signaling Mechanisms to Synthetic Modulators

Rim, E. Y., Clevers, H. & Nusse, R., 21 Jun 2022, In: Annual Review of Biochemistry. 91, p. 571-598 28 p.

Research output: Contribution to journal/periodical › Book/Film/Article review › Scientific

168 Citations (Scopus)

2021

A CRISPR/Cas9 genetically engineered organoid biobank reveals essential host factors for coronaviruses

Beumer, J., Geurts, M. H., Lamers, M. M., Puschhof, J., Zhang, J., van der Vaart, J., Mykytyn, A. Z., Breugem, T. I., Riesebosch, S., Schipper, D., van den Doel, P. B., de Lau, W., Pleguezuelos-Manzano, C., Busslinger, G., Haagmans, B. L. & Clevers, H., 17 Sept 2021, In: Nature Communications. 12, 1, p. 5498

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

Open Access

51 Citations (Scopus)

Adult mouse and human organoids derived from thyroid follicular cells and modeling of Graves' hyperthyroidism

van der Vaart, J., Bosmans, L., Sijbesma, S. F., Knoops, K., van de Wetering, W. J., Otten, H. G., Begthel, H., Borel Rinkes, I. H. M., Korving, J., Lentjes, E. G. W. M., Lopez-Iglesias, C., Peters, P. J., van Santen, H. M., Vriens, M. R. & Clevers, H., 21 Dec 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 51

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

Open Access

25 Citations (Scopus)

Advancing lung organoids for COVID-19 research

van der Vaart, J., Lamers, M. M., Haagmans, B. L. & Clevers, H., 01 Jun 2021, In: Disease Models & Mechanisms. 14, 6

Research output: Contribution to journal/periodical › Book/Film/Article review › Scientific

Open Access

34 Citations (Scopus)

Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma

De Crignis, E., Hossain, T., Romal, S., Carofiglio, F., Moulos, P., Khalid, M. M., Rao, S., Bazrafshan, A., Verstegen, M. M., Pourfarzad, F., Koutsothanassis, C., Gehart, H., Kan, T. W., Palstra, R-J., Boucher, C., IJzermans, J. N., Huch, M., Boj, S. F., Vries, R., Clevers, H., & 3 othersvan der Laan, L. J., Hatzis, P. & Mahmoudi, T., 30 Jul 2021, In: eLife. 10

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Open Access

61 Citations (Scopus)

Arrest of WNT/β-catenin signaling enables the transition from pluripotent to differentiated germ cells in mouse ovaries

Le Rolle, M., Massa, F., Siggers, P., Turchi, L., Loubat, A., Koo, B-K., Clevers, H., Greenfield, A., Schedl, A., Chaboissier, M-C. & Chassot, A-A., 27 Jul 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 30

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

Open Access

17 Citations (Scopus)

A turquoise fluorescence lifetime-based biosensor for quantitative imaging of intracellular calcium

van der Linden, F. H., Mahlandt, E. K., Arts, J. J. G., Beumer, J., Puschhof, J., de Man, S. M. A., Chertkova, A. O., Ponsioen, B., Clevers, H., van Buul, J. D., Postma, M., Gadella, T. W. J. & Goedhart, J., 09 Dec 2021, In: Nature Communications. 12, 1, p. 7159

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

Open Access

40 Citations (Scopus)

Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids

06 May 2021, In: Cell Stem Cell. 28, 5, p. 816-832 17 p.

Research output: Contribution to journal/periodical › Book/Film/Article review › Scientific

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158 Citations (Scopus)

Culture and analysis of kidney tubuloids and perfused tubuloid cells-on-a-chip

Gijzen, L., Yousef Yengej, F. A., Schutgens, F., Vormann, M. K., Ammerlaan, C. M. E., Nicolas, A., Kurek, D., Vulto, P., Rookmaaker, M. B., Lanz, H. L., Verhaar, M. C. & Clevers, H., Apr 2021, In: Nature Protocols. 16, 4, p. 2023-2050 28 p.

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45 Citations (Scopus)

Cysteamine-bicalutamide combination therapy corrects proximal tubule phenotype in cystinosis

Jamalpoor, A., van Gelder, C. A., Yousef Yengej, F. A., Zaal, E. A., Berlingerio, S. P., Veys, K. R., Pou Casellas, C., Voskuil, K., Essa, K., Ammerlaan, C. M., Rega, L. R., van der Welle, R. E., Lilien, M. R., Rookmaaker, M. B., Clevers, H., Klumperman, J., Levtchenko, E., Berkers, C. R., Verhaar, M. C., Altelaar, M., & 2 othersMasereeuw, R. & Janssen, M. J., 07 Jul 2021, In: EMBO Molecular Medicine. 13, 7, p. e13067

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24 Citations (Scopus)

Derivation of snake venom gland organoids for in vitro venom production

Puschhof, J., Post, Y., Beumer, J., Kerkkamp, H. M., Bittenbinder, M., Vonk, F. J., Casewell, N. R., Richardson, M. K. & Clevers, H., Mar 2021, In: Nature Protocols. 16, 3, p. 1494-1510 17 p.

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

Open Access

11 Citations (Scopus)

Diffuse Hormonal Systems

Clevers, H., 2021, In: Endotext.

Research output: Contribution to journal/periodical › Book/Film/Article review › Scientific

Disease modeling following organoid-based expansion of airway epithelial cells

Eenjes, E., van Riet, S., Kroon, A. A., Slats, A. M., Khedoe, P. P. S. J., Boerema-de Munck, A., Buscop-van Kempen, M., Ninaber, D. K., Reiss, I. K. M., Clevers, H., Rottier, R. J. & Hiemstra, P. S., 01 Oct 2021, In: American journal of physiology. Lung cellular and molecular physiology. 321, 4, p. L775-L786

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

19 Citations (Scopus)

Early invasion of the bladder wall by solitary bacteria protects UPEC from antibiotics and neutrophil swarms in an organoid model

Sharma, K., Thacker, V. V., Dhar, N., Clapés Cabrer, M., Dubois, A., Signorino-Gelo, F., Mullenders, J., Knott, G. W., Clevers, H. & McKinney, J. D., 20 Jul 2021, In: Cell Reports. 36, 3, p. 109351

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Open Access

14 Citations (Scopus)

Evaluating CRISPR-based prime editing for cancer modeling and CFTR repair in organoids

Geurts, M. H., de Poel, E., Pleguezuelos-Manzano, C., Oka, R., Carrillo, L., Andersson-Rolf, A., Boretto, M., Brunsveld, J. E., van Boxtel, R., Beekman, J. M. & Clevers, H., Oct 2021, In: Life science alliance. 4, 10

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Open Access

69 Citations (Scopus)

Evidence generation and reproducibility in cell and gene therapy research: A call to action

Abou-El-Enein, M., Angelis, A., Appelbaum, F. R., Andrews, N. C., Bates, S. E., Bierman, A. S., Brenner, M. K., Cavazzana, M., Caligiuri, M. A., Clevers, H., Cooke, E., Daley, G. Q., Dzau, V. J., Ellis, L. M., Fineberg, H. V., Goldstein, L. S. B., Gottschalk, S., Hamburg, M. A., Ingber, D. E., Kohn, D. B., & 15 othersKrainer, A. R., Maus, M. V., Marks, P., Mummery, C. L., Pettigrew, R. I., Rutter, J. L., Teichmann, S. A., Terzic, A., Urnov, F. D., Williams, D. A., Wolchok, J. D., Lawler, M., Turtle, C. J., Bauer, G. & Ioannidis, J. P. A., 10 Sept 2021, In: Molecular therapy. Methods & clinical development. 22, p. 11-14 4 p.

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9 Citations (Scopus)

EWSR1-WT1 Target Genes and Therapeutic Options Identified in a Novel DSRCT In Vitro Model

Bleijs, M., Pleijte, C., Engels, S., Ringnalda, F., Meyer-Wentrup, F., van de Wetering, M. & Clevers, H., 02 Dec 2021, In: Cancers. 13, 23

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12 Citations (Scopus)

Exploring the human lacrimal gland using organoids and single-cell sequencing

Bannier-Hélaouët, M., Post, Y., Korving, J., Trani Bustos, M., Gehart, H., Begthel, H., Bar-Ephraim, Y. E., van der Vaart, J., Kalmann, R., Imhoff, S. M. & Clevers, H., 01 Jul 2021, In: Cell Stem Cell. 28, 7, p. 1221-1232.e7

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64 Citations (Scopus)

Host phospholipid peroxidation fuels ExoU-dependent cell necrosis and supports Pseudomonas aeruginosa-driven pathology

Bagayoko, S., Leon-Icaza, S. A., Pinilla, M., Hessel, A., Santoni, K., Péricat, D., Bordignon, P-J., Moreau, F., Eren, E., Boyancé, A., Naser, E., Lefèvre, L., Berrone, C., Iakobachvili, N., Metais, A., Rombouts, Y., Lugo-Villarino, G., Coste, A., Attrée, I., Frank, D. W., & 5 othersClevers, H., Peters, P. J., Cougoule, C., Planès, R. & Meunier, E., Sept 2021, In: PLoS Pathogens. 17, 9, p. e1009927

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11 Citations (Scopus)

Human gastrointestinal epithelia of the esophagus, stomach, and duodenum resolved at single-cell resolution

Busslinger, G. A., Weusten, B. L. A., Bogte, A., Begthel, H., Brosens, L. A. A. & Clevers, H., 09 Mar 2021, In: Cell Reports. 34, 10, p. 108819

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Open Access

139 Citations (Scopus)

Identification of novel human Wnt target genes using adult endodermal tissue-derived organoids

Boonekamp, K. E., Heo, I., Artegiani, B., Asra, P., van Son, G., de Ligt, J. & Clevers, H., Jun 2021, In: Developmental Biology. 474, p. 37-47 11 p.

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22 Citations (Scopus)

Integration of metabolomics, genomics, and immune phenotypes reveals the causal roles of metabolites in disease

Chu, X., Jaeger, M., Beumer, J., Bakker, O. B., Aguirre-Gamboa, R., Oosting, M., Smeekens, S. P., Moorlag, S., Mourits, V. P., Koeken, V. A. C. M., de Bree, C., Jansen, T., Mathews, I. T., Dao, K., Najhawan, M., Watrous, J. D., Joosten, I., Sharma, S., Koenen, H. J. P. M., Withoff, S., & 13 othersJonkers, I. H., Netea-Maier, R. T., Xavier, R. J., Franke, L., Xu, C-J., Joosten, L. A. B., Sanna, S., Jain, M., Kumar, V., Clevers, H., Wijmenga, C., Netea, M. G. & Li, Y., 06 Jul 2021, In: Genome Biology. 22, 1, p. 198

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Open Access

29 Citations (Scopus)

Intestinal organoid cocultures with microbes

Puschhof, J., Pleguezuelos-Manzano, C., Martinez-Silgado, A., Akkerman, N., Saftien, A., Boot, C., de Waal, A., Beumer, J., Dutta, D., Heo, I. & Clevers, H., Oct 2021, In: Nature Protocols. 16, 10, p. 4633-4649 17 p.

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Open Access

116 Citations (Scopus)

KSR1- and ERK-dependent translational regulation of the epithelial-to-mesenchymal transition

Rao, C., Frodyma, D. E., Southekal, S., Svoboda, R. A., Black, A. R., Guda, C., Mizutani, T., Clevers, H., Johnson, K. R., Fisher, K. W. & Lewis, R. E., 10 May 2021, In: eLife. 10

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Open Access

12 Citations (Scopus)

Long-term culture, genetic manipulation and xenotransplantation of human normal and breast cancer organoids

Dekkers, J. F., van Vliet, E. J., Sachs, N., Rosenbluth, J. M., Kopper, O., Rebel, H. G., Wehrens, E. J., Piani, C., Visvader, J. E., Verissimo, C. S., Boj, S. F., Brugge, J. S., Clevers, H. & Rios, A. C., Apr 2021, In: Nature Protocols. 16, 4, p. 1936-1965 30 p.

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Open Access

111 Citations (Scopus)

Medium-Throughput Drug- and Radiotherapy Screening Assay using Patient-Derived Organoids

Putker, M., Millen, R., Overmeer, R., Driehuis, E., Zandvliet, M. M. J. M., Clevers, H., Boj, S. F. & Li, Q-X., 30 Apr 2021, In: Journal of Visualized Experiments. 170

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12 Citations (Scopus)

Modelling of primary ciliary dyskinesia using patient-derived airway organoids

van der Vaart, J., Böttinger, L., Geurts, M. H., van de Wetering, W. J., Knoops, K., Sachs, N., Begthel, H., Korving, J., Lopez-Iglesias, C., Peters, P. J., Eitan, K., Gileles-Hillel, A. & Clevers, H., 06 Dec 2021, In: EMBO Reports. 22, 12, p. e52058

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Open Access

19 Citations (Scopus)

Molecular characterization of Barrett's esophagus at single-cell resolution

Busslinger, G. A., de Barbanson, B., Oka, R., Weusten, B. L. A., de Maat, M., van Hillegersberg, R., Brosens, L. A. A., van Boxtel, R., van Oudenaarden, A. & Clevers, H., 23 Nov 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 47

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Open Access

11 Citations (Scopus)

National Heart, Lung, and Blood Institute and Building Respiratory Epithelium and Tissue for Health (BREATH) Consortium Workshop Report: Moving Forward in Lung Regeneration

Hynds, R. E., Zacharias, W. J., Nikolić, M. Z., Königshoff, M., Eickelberg, O., Gosens, R., de Coppi, P., Janes, S. M., Morrisey, E., Clevers, H., Ryan, A. L., Stripp, B. R., Sun, X., Kim, C. F. & Lin, Q. S., Jul 2021, In: American journal of respiratory cell and molecular biology. 65, 1, p. 22-29 8 p.

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1 Citation (Scopus)

NOTUM from Apc-mutant cells biases clonal competition to initiate cancer

Flanagan, D. J., Pentinmikko, N., Luopajärvi, K., Willis, N. J., Gilroy, K., Raven, A. P., Mcgarry, L., Englund, J. I., Webb, A. T., Scharaw, S., Nasreddin, N., Hodder, M. C., Ridgway, R. A., Minnee, E., Sphyris, N., Gilchrist, E., Najumudeen, A. K., Romagnolo, B., Perret, C., Williams, A. C., & 16 othersClevers, H., Nummela, P., Lähde, M., Alitalo, K., Hietakangas, V., Hedley, A., Clark, W., Nixon, C., Kirschner, K., Jones, E. Y., Ristimäki, A., Leedham, S. J., Fish, P. V., Vincent, J-P., Katajisto, P. & Sansom, O. J., Jun 2021, In: Nature. 594, 7863, p. 430-435 6 p.

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117 Citations (Scopus)

Organoids and organs-on-chips: Insights into human gut-microbe interactions

Puschhof, J., Pleguezuelos-Manzano, C. & Clevers, H., 09 Jun 2021, In: Cell Host & Microbe. 29, 6, p. 867-878 12 p.

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95 Citations (Scopus)

Patient-derived organoids model cervical tissue dynamics and viral oncogenesis in cervical cancer

Lõhmussaar, K., Oka, R., Espejo Valle-Inclan, J., Smits, M. H. H., Wardak, H., Korving, J., Begthel, H., Proost, N., van de Ven, M., Kranenburg, O. W., Jonges, T. G. N., Zweemer, R. P., Veersema, S., van Boxtel, R. & Clevers, H., 05 Aug 2021, In: Cell Stem Cell. 28, 8, p. 1380-1396.e6

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107 Citations (Scopus)

PolyG-DS: An ultrasensitive polyguanine tract-profiling method to detect clonal expansions and trace cell lineage

Zhang, Y., Kohrn, B. F., Yang, M., Nachmanson, D., Soong, T. R., Lee, I-H., Tao, Y., Clevers, H., Swisher, E. M., Brentnall, T. A., Loeb, L. A., Kennedy, S. R., Salk, J. J., Naxerova, K. & Risques, R. A., 03 Aug 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 31

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Open Access

Promises and Challenges of Organoid-Guided Precision Medicine

Bose, S., Clevers, H. & Shen, X., 10 Sept 2021, In: Med (New York, N.Y.). 2, 9, p. 1011-1026 16 p.

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71 Citations (Scopus)

SARS-CoV-2 infection and replication in human gastric organoids

Giobbe, G. G., Bonfante, F., Jones, B. C., Gagliano, O., Luni, C., Zambaiti, E., Perin, S., Laterza, C., Busslinger, G., Stuart, H., Pagliari, M., Bortolami, A., Mazzetto, E., Manfredi, A., Colantuono, C., Di Filippo, L., Pellegata, A. F., Panzarin, V., Thapar, N., Li, V. S. W., & 5 othersEaton, S., Cacchiarelli, D., Clevers, H., Elvassore, N. & De Coppi, P., 16 Nov 2021, In: Nature Communications. 12, 1, p. 6610

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Open Access

45 Citations (Scopus)

Single-cell atlas of developing murine adrenal gland reveals relation of Schwann cell precursor signature to neuroblastoma phenotype

Hanemaaijer, E. S., Margaritis, T., Sanders, K., Bos, F. L., Candelli, T., Al-Saati, H., van Noesel, M. M., Meyer-Wentrup, F. A. G., van de Wetering, M., Holstege, F. C. P. & Clevers, H., 02 Feb 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 5

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44 Citations (Scopus)

Single-cell Ribo-seq reveals cell cycle-dependent translational pausing

VanInsberghe, M., van den Berg, J., Andersson-Rolf, A., Clevers, H. & van Oudenaarden, A., Sept 2021, In: Nature. 597, 7877, p. 561-565 5 p.

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76 Citations (Scopus)

SIRT1 inhibitors mitigate radiation-induced GI syndrome by enhancing intestinal-stem-cell survival

Fu, G., Chen, S., Liang, L., Li, X., Tang, P., Rao, X., Pan, M., Xu, X., Li, Y., Yao, Y., Zhou, Y., Gao, J., Mo, S., Cai, S., Peng, J., Zhang, Z., Clevers, H., Gao, J. & Hua, G., 31 Mar 2021, In: Cancer letters. 501, p. 20-30 11 p.

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28 Citations (Scopus)

The frontier of live tissue imaging across space and time

Huang, Q., Garrett, A., Bose, S., Blocker, S., Rios, A. C., Clevers, H. & Shen, X., 01 Apr 2021, In: Cell Stem Cell. 28, 4, p. 603-622 20 p.

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26 Citations (Scopus)

The H3.3K27M oncohistone affects replication stress outcome and provokes genomic instability in pediatric glioma

Bočkaj, I., Martini, T. E. I., de Camargo Magalhães, E. S., Bakker, P. L., Meeuwsen-de Boer, T. G. J., Armandari, I., Meuleman, S. L., Mondria, M. T., Stok, C., Kok, Y. P., Bakker, B., Wardenaar, R., Seiler, J., Broekhuis, M. J. C., van den Bos, H., Spierings, D. C. J., Ringnalda, F. C. A., Clevers, H., Schüller, U., van Vugt, M. A. T. M., & 2 othersFoijer, F. & Bruggeman, S. W. M., Nov 2021, In: PLoS Genetics. 17, 11, p. e1009868

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

Open Access

17 Citations (Scopus)

The Organoid Cell Atlas

Jan 2021, In: Nature Biotechnology. 39, 1, p. 13-17 5 p.

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

Open Access

93 Citations (Scopus)

Hans Clevers

Research output

Search results