Research output per year
Research output per year
Research output
- 18 Article
- 18 results
Search results
-
2024
Cortical CD200-CD200R and CD47-SIRPα expression is associated with multiple sclerosis pathology
van den Bosch, A. M. R., Wever, D., Schonewille, P., Schuller, S. L., Smolders, J., Hamann, J. & Huitinga, I., 20 Aug 2024, In: Brain communications. 6, 4, p. fcae264Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile92 Downloads (Pure) -
Disentangling the heterogeneity of multiple sclerosis through identification of independent neuropathological dimensions
de Boer, A., van den Bosch, A. M. R., Mekkes, N. J., Fransen, N. L., Dagkesamanskaia, E., Hoekstra, E., Hamann, J., Smolders, J., Huitinga, I. & Holtman, I. R., 21 May 2024, In: Acta Neuropathologica. 147, 1, p. 90Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile1 Citation (Scopus)45 Downloads (Pure) -
Modification of T- and B-cell-associated immuno-pathologic mechanisms in multiple sclerosis by disease modifying therapies: Achievements and opportunities
Smolders, J., Hamann, J. & Huitinga, I., Aug 2024, In: Handbook of Clinical Neurology. 202, p. 7-21 15 p.Research output: Contribution to journal/periodical › Article › Scientific › peer-review
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Profiling of microglia nodules in multiple sclerosis reveals propensity for lesion formation
van den Bosch, A. M. R., van der Poel, M., Fransen, N. L., Vincenten, M. C. J., Bobeldijk, A. M., Jongejan, A., Engelenburg, H. J., Moerland, P. D., Smolders, J., Huitinga, I. & Hamann, J., 23 Feb 2024, In: Nature Communications. 15, 1, p. 1667Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile7 Citations (Scopus)40 Downloads (Pure) -
2023
Microglia transcriptional profiling in major depressive disorder shows inhibition of cortical grey matter microglia
Scheepstra, K. W. F., Mizee, M. R., van Scheppingen, J., Adelia, A., Wever, D. D., Mason, M. R. J., Dubbelaar, M. L., Hsiao, C-C., Eggen, B. J. L., Hamann, J. & Huitinga, I., 28 Apr 2023, In: Biological Psychiatry. 94, p. 619-629Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile14 Citations (Scopus)79 Downloads (Pure) -
Osteopontin associates with brain TRM-cell transcriptome and compartmentalization in donors with and without multiple sclerosis
Hsiao, C-C., Engelenburg, H. J., Jongejan, A., Zhu, J., Zhang, B., Mingueneau, M., Moerland, P. D., Huitinga, I., Smolders, J. & Hamann, J., 01 Jan 2023, In: iScience. 26, 1, p. 105785Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile9 Citations (Scopus)57 Downloads (Pure) -
Selective emergence of antibody-secreting cells in the multiple sclerosis brain
Bogers, L., Engelenburg, H. J., Janssen, M., Unger, P-P. A., Melief, M-J., Wierenga-Wolf, A. F., Hsiao, C-C., Mason, M. R. J., Hamann, J., van Langelaar, J., Smolders, J. & van Luijn, M. M., 14 Feb 2023, In: EBioMedicine. 89, p. 104465Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile11 Citations (Scopus)49 Downloads (Pure) -
The adhesion G protein-coupled receptor GPR56/ADGRG1 in cytotoxic lymphocytes
Hsiao, C-C., Vos, E., van Gisbergen, K. P. J. M. & Hamann, J., 07 Feb 2023, In: Basic & clinical pharmacology & toxicology. 133, p. 286-294Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile3 Citations (Scopus)56 Downloads (Pure) -
Ultrastructural axon-myelin unit alterations in MS correlate with inflammation
van den Bosch, A. M. R., Hümmert, S., Steyer, A., Ruhwedel, T., Hamann, J., Smolders, J., Nave, K-A., Stadelmann, C., Kole, M. H. P., Möbius, W. & Huitinga, I., Jan 2023, In: Annals of Neurology. 93, p. 856-870Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile15 Citations (Scopus)59 Downloads (Pure) -
2022
Programmed Cell Death Protein 1-Positive CD8+ T Cells in Multiple Sclerosis: Exhausted Fighters or Peacekeepers
Smolders, J. & Hamann, J., Jul 2022, In: Neurology(R) neuroimmunology & neuroinflammation. 9, 4, e1173.Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile4 Citations (Scopus)31 Downloads (Pure) -
T-cell surveillance of the human brain in health and multiple sclerosis
Smolders, J., van Luijn, M. M., Hsiao, C-C. & Hamann, J., 01 Apr 2022, In: Seminars in immunopathology. 44, p. 855-867Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile15 Citations (Scopus)28 Downloads (Pure) -
2021
Absence of B Cells in Brainstem and White Matter Lesions Associates With Less Severe Disease and Absence of Oligoclonal Bands in MS
Fransen, N. L., de Jong, B. A., Heß, K., Kuhlmann, T., Vincenten, M. C. J., Hamann, J., Huitinga, I. & Smolders, J., 2021, In: Neurology(R) neuroimmunology & neuroinflammation. 8, 2, e955.Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile19 Citations (Scopus)164 Downloads (Pure) -
GPCRomics of Homeostatic and Disease-Associated Human Microglia
Hsiao, C-C., Sankowski, R., Prinz, M., Smolders, J., Huitinga, I. & Hamann, J., 2021, In: Frontiers in Immunology. 12, p. 674189Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile21 Citations (Scopus)213 Downloads (Pure) -
Multiple Targets for Oxysterols in Their Regulation of the Immune System
Reinmuth, L., Hsiao, C-C., Hamann, J., Rosenkilde, M. & Mackrill, J., Aug 2021, In: Cells. 10, 8, 2078.Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile12 Citations (Scopus)85 Downloads (Pure) -
White matter lesions in multiple sclerosis are enriched for CD20dim CD8+ tissue-resident memory T cells
Hsiao, C-C., Fransen, N. L., van den Bosch, A. M. R., Brandwijk, K. I. M., Huitinga, I., Hamann, J. & Smolders, J., 2021, In: European Journal of Immunology. 51, p. 483-486Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open Access21 Citations (Scopus) -
2020
IgG Immune Complexes Break Immune Tolerance of Human Microglia
van der Poel, M., Hoepel, W., Hamann, J., Huitinga, I. & Dunnen, J. D., 2020, In: Journal of Immunology. 205, p. 2511-2518Research output: Contribution to journal/periodical › Article › Scientific › peer-review
23 Citations (Scopus) -
Single-cell mass cytometry reveals complex myeloid cell composition in active lesions of progressive multiple sclerosis
Böttcher, C., van der Poel, M., Fernández-Zapata, C., Schlickeiser, S., Leman, J. K. H., Hsiao, C-C., Mizee, M. R., Adelia, Vincenten, M. C. J., Kunkel, D., Huitinga, I., Hamann, J. & Priller, J., 2020, In: Acta neuropathologica communications. 8, 1, p. 136Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile37 Citations (Scopus)81 Downloads (Pure) -
2019
Macrophages Do Not Express the Phagocytic Receptor BAI1/
Hsiao, C-C., van der Poel, M., van Ham, T. J. & Hamann, J., 2019, In: Frontiers in Immunology. 10, p. 962Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open AccessFile15 Citations (Scopus)119 Downloads (Pure)