20022019

Research output per year

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Personal profile

About

Jeroen Bakkers received his PhD in 2000 from Leiden University, The Netherlands. During this time he was introduced in the zebrafish system and used it to study the role of glycosyltransferases during early vertebrate development. He continued his work on zebrafish development as a postdoc in the lab of Matthias Hammerschmidt at the Max-Planck Institute for Immunbiology in Freiburg, Germany. Here he started his work on Bmp and Wnt signaling during zebrafish gastrulation and isolated p63 (a member of the p53 tumor suppressor family) as a direct target of Bmp signalling. In 2003 he was appointed at the Hubrecht Institute initially as a junior staff member and in 2008 as a senior staff member and initiated here his work on heart development using zebrafish. In 2008 he was awarded a VIDI career grant from the Dutch science organization NWO and in 2015 he was appointed as Professor of Molecular Cardiogenetics at the UMC Utrecht.

j.bakkers(at)hubrecht.eu

External positions

Professor

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Research Output

  • 84 Article
  • 1 Contribution to conference proceedings

ABCC9-related Intellectual disability Myopathy Syndrome is a KATP channelopathy with loss-of-function mutations in ABCC9

Smeland, M. F., McClenaghan, C., Roessler, H. I., Savelberg, S., Hansen, G. Å. M., Hjellnes, H., Arntzen, K. A., Müller, K. I., Dybesland, A. R., Harter, T., Sala-Rabanal, M., Emfinger, C. H., Huang, Y., Singareddy, S. S., Gunn, J., Wozniak, D. F., Kovacs, A., Massink, M., Tessadori, F., Kamel, S. M. & 5 others, Bakkers, J., Remedi, M. S., Van Ghelue, M., Nichols, C. G. & van Haaften, G., 01 Oct 2019, In : Nature Communications. 10, 1, p. 4457

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access
  • A de novo variant in the human HIST1H4J gene causes a syndrome analogous to the HIST1H4C-associated neurodevelopmental disorder

    Tessadori, F., Rehman, A. U., Giltay, J. C., Xia, F., Streff, H., Duran, K., Bakkers, J., Lalani, S. R. & van Haaften, G., 05 Dec 2019, In : European Journal of Human Genetics.

    Research output: Contribution to journal/periodicalArticleScientificpeer-review

    Open Access
  • Assessment of the Most Optimal Control Tissue for Intracranial Aneurysm Gene Expression Studies

    Laarman, M. D., Kleinloog, R., Bakker, M. K., Rinkel, G. J. E., Bakkers, J. & Ruigrok, Y. M., Oct 2019, In : Stroke. 50, 10, p. 2933-2936 4 p.

    Research output: Contribution to journal/periodicalArticleScientificpeer-review

  • Chromatin Conformation Links Putative Enhancers in Intracranial Aneurysm-Associated Regions to Potential Candidate Genes

    07 May 2019, In : Journal of the American Heart Association. 8, 9, p. e011201

    Research output: Contribution to journal/periodicalArticleScientificpeer-review

    Open Access
  • Chromatin conformation links putative enhancers in intracranial aneurysm-associated regions to potential candidate genes.

    Laarman, M., Geeven, G., Barnett, P., Rinkel, G. J. E., de Laat, W., Ruigrok, Y. M. & Bakkers, J., 2019, In : Journal of the American Heart Association. 8, e011201.

    Research output: Contribution to journal/periodicalArticleScientificpeer-review

    Open Access
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