Personal profile
About
Jeroen Bakkers received his PhD in 2000 from Leiden University, The Netherlands. During this time he was introduced in the zebrafish system and used it to study the role of glycosyltransferases during early vertebrate development. He continued his work on zebrafish development as a postdoc in the lab of Matthias Hammerschmidt at the Max-Planck Institute for Immunbiology in Freiburg, Germany. Here he started his work on Bmp and Wnt signaling during zebrafish gastrulation and isolated p63 (a member of the p53 tumor suppressor family) as a direct target of Bmp signalling. In 2003 he was appointed at the Hubrecht Institute initially as a junior staff member and in 2008 as a senior staff member and initiated here his work on heart development using zebrafish. In 2008 he was awarded a VIDI career grant from the Dutch science organization NWO and in 2015 he was appointed as Professor of Molecular Cardiogenetics at the UMC Utrecht.
j.bakkers(at)hubrecht.eu
External positions
Professor, Utrecht University
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
-
Broad Vitamin B6-Related Metabolic Disturbances in a Zebrafish Model of Hypophosphatasia (TNSALP-Deficiency)
Ciapaite, J., Albersen, M., Savelberg, S. M. C., Bosma, M., Meijer, N. W. F., Tessadori, F., Bakkers, J. P. W., van Haaften, G., Jans, J. J. & Verhoeven-Duif, N. M., 01 Apr 2025, In: International Journal of Molecular Sciences. 26, 7Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open Access1 Citation (Scopus) -
Cross-species comparison reveals that Hmga1 reduces H3K27me3 levels to promote cardiomyocyte proliferation and cardiac regeneration
Bouwman, M., de Bakker, D. E. M., Honkoop, H., Giovou, A. E., Versteeg, D., Boender, A. R., Nguyen, P. D., Slotboom, M., Colquhoun, D., Vigil-Garcia, M., Kooijman, L., Janssen, R., Hooijkaas, I. B., Günthel, M., Visser, K. J., Klerk, M., Zentilin, L., Giacca, M., Kaslin, J. & Boink, G. J. J. & 3 others, , 02 Jan 2025, In: Nature cardiovascular research. 4, 1, p. 64-82 19 p.Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open Access12 Citations (Scopus) -
Oxidative phosphorylation is required for cardiomyocyte re-differentiation and long-term fish heart regeneration
Lekkos, K., Hu, Z., Nguyen, P. D., Honkoop, H., Sengul, E., Alonaizan, R., Koth, J., Ying, J., Lemieux, M. E., Kenward, A., Keeley, S., Spanjaard, B., Kennedy, B. W. C., Sun, X., Banecki, K., Potts, H. G., Ruggiero, G., Montgomery, J., Panáková, D. & Junker, J. P. & 5 others, , 01 Oct 2025, In: Nature cardiovascular research. 4, 10, p. 1363-1380 18 p.Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open Access4 Citations (Scopus) -
Biallelic variants in FLII cause pediatric cardiomyopathy by disrupting cardiomyocyte cell adhesion and myofibril organization
Ruijmbeek, C. W., Housley, F., Idrees, H., Housley, M. P., Pestel, J., Keller, L., Lai, J. K., der Linde, H. C. V., Willemsen, R., Piesker, J., Al-Hassnan, Z. N., Almesned, A., Dalinghaus, M., den Bersselaar, L. M. V., van Slegtenhorst, M. A., Tessadori, F., Bakkers, J., van Ham, T. J., Stainier, D. Y. & Verhagen, J. M. & 1 others, , 08 Sept 2023, In: JCI insight. 8, 17Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open Access4 Citations (Scopus) -
From mechanisms of heart failure to clinical heart success
Bakkers, J., Bellin, M., Hmeljak, J. & Karra, R., 01 May 2023, In: Disease Models & Mechanisms. 16, 5Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open Access1 Citation (Scopus)
Prizes
Activities
-
Developmental Dynamics (Journal)
Bakkers, J. (Peer reviewer / referee)
22 Nov 2025Activity: Publication peer-review and editorial work › Publication peer-review
-
Future of cardiac regenerative therapy: Adult perspective
Bakkers, J. (Invited speaker)
21 Nov 2025Activity: Talk or presentation › Academic
-
The Fish that Heals: Unraveling the Mysteries of Cardiac Regeneration
Bakkers, J. (Invited speaker)
09 Oct 2025Activity: Talk or presentation › Academic
-
Interspecies comparison reveals a novel mechanism of cardiac regeneration
Bakkers, J. (Invited speaker)
13 Mar 2025Activity: Talk or presentation › Academic
-
The Fish that Heals: Unraveling the Mysteries of Cardiac Regeneration
Bakkers, J. (Invited speaker)
13 Mar 2025Activity: Talk or presentation › Academic
Press/Media
-
-
Van zebravis tot robothart: fascinerende onderzoeken in talkshow Hartzaken
04/10/2023
1 Media contribution
Press/Media: Expert Comment
-
Resultaat van de maand: hartregeneratie-expert Jeroen Bakkers
13/06/2023
1 Media contribution
Press/Media: Expert Comment
-
Schade menselijk hart te repareren dankzij zebravisje
30/05/2023
1 item of Media coverage
Press/Media: Research
-
Zebrafish Heart Regeneration – Researchers used ex vivo imaging to visualize intracellular calcium dynamics in the regenerating zebrafish heart.
30/05/2023
1 Media contribution
Press/Media: Expert Comment