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2020

Calcium-Sensing Receptor Mediates β-Amyloid-Induced Synaptic Formation Impairment and Cognitive Deficits via Regulation of Cytosolic Phospholipase A2/Prostaglandin E2 Metabolic Pathway

Feng, C., Bao, X., Shan, L., Ling, Y., Ding, Y., Wang, J., Cao, Y., Wang, Q., Cui, W. & Xu, S., 2020, In : Frontiers in aging neuroscience. 12, p. 144

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Gestational Factors throughout Fetal Neurodevelopment: The Serotonin Link

Hanswijk, S. I., Spoelder, M., Shan, L., Verheij, M. M. M., Muilwijk, O. G., Li, W., Liu, C., Kolk, S. M. & Homberg, J. R., 2020, In : International Journal of Molecular Sciences. 21, 16, E5850.

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SIRT1 attenuates the neurotoxicity associated with Alzheimer's disease, via a mechanism which may involve regulation of peroxisome proliferator-activated receptor γ coactivator 1-α

Dong, Y-T., Cao, K., Xiang, J., Shan, L. & Guan, Z-Z., 2020, In : The American journal of pathology. 190, p. 1545-1564

Research output: Contribution to journal/periodicalArticleScientificpeer-review

2019

Astrocyte changes in the prefrontal cortex from aged non-suicidal depressed patients.

Qi, X-R., Kamphuis, W. & Shan, L., 2019, In : Frontiers in Cellular Neuroscience. 13, 503.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

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Histamine-4 receptor antagonist JNJ7777120 inhibits pro-inflammatory microglia and prevents the progression of Parkinson-like pathology and behaviour in a rat model

Zhou, P., Homberg, J. R., Fang, Q., Wang, J., Li, W., Meng, X., Shen, J., Luan, Y., Liao, P., Swaab, D. F., Shan, L. & Liu, C., 2019, In : Brain, Behavior, and Immunity. 76, p. 61-73

Research output: Contribution to journal/periodicalArticleScientificpeer-review

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100 Downloads (Pure)
2018

Impaired fear extinction in serotonin transporter knockout rats is associated with increased 5-hydroxymethylcytosine in the amygdala

Shan, L., Guo, H-Y., van den Heuvel, C. N. A. M., van Heerikhuize, J. J. & Homberg, J. R., Jul 2018, In : CNS Neuroscience and Therapeutics. 24, p. 810-819

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Opiates increase the number of hypocretin-producing cells in human and mouse brain and reverse cataplexy in a mouse model of narcolepsy.

Thannickal, T. C., John, J., Shan, L., Swaab, D. F., Wu, M. F., Ramanathan, L., McGregor, R., Chew, K. T., Cornford, M., Yamanaka, A., Inutsuka, A., Fronczek, R., Lammers, G. J., Worley, P. F. & Siegel, J. M., 27 Jun 2018, In : Science Translational Medicine. 10, eaao4953.

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293 Downloads (Pure)
2013

Neuronal histaminergic system in aging and age-related neurodegenerative disorders.

Shan, L., Swaab, D. F. & Bao, A. M., 2013, In : Experimental Gerontology. 48, p. 603-607

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Unaltered histaminergic system in depression: A postmortem study.

Shan, L., Qi, X. R., Balesar, R. A., Swaab, D. F. & Bao, A. M., 2013, In : Journal of Affective Disorders. 146, p. 220-223

Research output: Contribution to journal/periodicalArticleScientificpeer-review

2012

Alterations in the histaminergic system in Alzheimer's disease: a postmortem study.

Shan, L., Bossers, C. A. M., Unmehopa, U. A., Bao, A. M. & Swaab, D. F., 2012, In : Neurobiology of Aging. 33, p. 2585-2598

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Alterations in the histaminergic system in the substantia nigra and striatum of Parkinson's patients: a postmortem study.

Shan, L., Bossers, C. A. M., Luchetti, S., Balesar, R. A., Lethbridge, N., Chazot, P. L., Bao, A. M. & Swaab, D. F., 2012, In : Neurobiology of Aging. 33, p. 1-13

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Diurnal fluctuation in histidine decarboxylase expression, the rate limiting enzyme for histamine production, and its disorder in neurodegenerative disease.

Shan, L., Hofman, M. A., Van Wamelen, D. J., Van Someren, E. J. W., Bao, A. M. & Swaab, D. F., 2012, In : Sleep. 35, p. 713-715

Research output: Contribution to journal/periodicalArticleScientificpeer-review

2011

Functional increase of brain histaminergic signaling in Huntington's disease.

van Wamelen, D. J., Shan, L., Aziz, N. A., Anink, J. J., Bao, A. M., Roos, R. A. & Swaab, D. F., 2011, In : Brain Pathology. 21, p. 419-427

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Presence of tissue transglutaminase in granular endoplasmic reticulum is characteristic of melanized neurons in Parkinson's disease brain.

Wilhelmus, M. M., Verhaar, R., Andringa, G., Bol, J. G. J. M., Cras, P., Shan, L., Hoozemans, J. J. M. & Drukarch, B., 2011, In : Brain Pathology. 21, p. 130-139

Research output: Contribution to journal/periodicalArticleScientificpeer-review

2010

A quantitative in situ hybridization protocol for formalin-fixed paraffin-embedded archival post-mortem human brain tissue.

Liu, C. Q., Shan, L., Balesar, R. A., Luchetti, S., van Heerikhuize, J. J., Luo, J. H., Swaab, D. F. & Bao, A. M., 2010, In : Methods. 52, p. 359-366

Research output: Contribution to journal/periodicalArticleScientificpeer-review