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Research Output

2020

Quantification of mRNA translation in live cells using single-molecule imaging

Khuperkar, D., Hoek, T. A., Sonneveld, S., Verhagen, B. M. P., Boersma, S. & Tanenbaum, M. E., Apr 2020, In : Nature Protocols. 15, 4, p. 1371-1398 28 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Sequencing metabolically labeled transcripts in single cells reveals mRNA turnover strategies

Battich, N., Beumer, J., de Barbanson, B., Krenning, L., Baron, C. S., Tanenbaum, M. E., Clevers, H. & van Oudenaarden, A., 06 Mar 2020, In : Science. 367, 6482, p. 1151-1156 6 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

2019

Live imaging of mRNA using RNA-stabilized fluorogenic proteins

Wu, J., Zaccara, S., Khuperkar, D., Kim, H., Tanenbaum, M. E. & Jaffrey, S. R., Sep 2019, In : Nature Methods. 16, 9, p. 862-865 4 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Multi-Color Single-Molecule Imaging Uncovers Extensive Heterogeneity in mRNA Decoding

Boersma, S., Khuperkar, D., Verhagen, B. M. P., Sonneveld, S., Grimm, J. B., Lavis, L. D. & Tanenbaum, M. E., 11 Jul 2019, In : Cell. 178, 2, p. 458-472.e19

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

Single-Molecule Imaging Uncovers Rules Governing Nonsense-Mediated mRNA Decay

Hoek, T. A., Khuperkar, D., Lindeboom, R. G. H., Sonneveld, S., Verhagen, B. M. P., Boersma, S., Vermeulen, M. & Tanenbaum, M. E., 25 Jul 2019, In : Molecular Cell. 75, 2, p. 324-339.e11

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access
2018

Imaging Translation Dynamics of Single mRNA Molecules in Live Cells

Ruijtenberg, S., Hoek, T. A., Yan, X. & Tanenbaum, M. E., 2018, In : Methods in Molecular Biology. 1649, p. 385-404 20 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

2017

Combined CRISPRi/a-Based Chemical Genetic Screens Reveal that Rigosertib Is a Microtubule-Destabilizing Agent

Jost, M., Chen, Y., Gilbert, L. A., Horlbeck, M. A., Krenning, L., Menchon, G., Rai, A., Cho, M. Y., Stern, J. J., Prota, A. E., Kampmann, M., Akhmanova, A., Steinmetz, M. O., Tanenbaum, M. E. & Weissman, J. S., 05 Oct 2017, In : Molecular Cell. 68, 1, p. 210-223.e6

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

Heterogeneity in kinesin function

Reddy, B. J. N., Tripathy, S., Vershinin, M., Tanenbaum, M. E., Xu, J., Mattson-Hoss, M., Arabi, K., Chapman, D., Doolin, T., Hyeon, C. & Gross, S. P., Oct 2017, In : Traffic. 18, 10, p. 658-671 14 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access
2016

Aurora A, MCAK, and Kif18b promote Eg5-independent spindle formation

van Heesbeen, R. G. H. P., Raaijmakers, J. A., Tanenbaum, M. E., Halim, V. A., Lelieveld, D., Lieftink, C., Heck, A. J. R., Egan, D. A. & Medema, R. H., 29 Jun 2016, In : Chromosoma.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

Dynamics of Translation of Single mRNA Molecules In Vivo

Yan, X., Hoek, T. A., Vale, R. D. & Tanenbaum, M. E., 05 May 2016, In : Cell. 165, 4, p. 976-89 14 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access