Research output per year
Research output per year
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Dive into the research topics where Wouter de Laat is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Building regulatory landscapes reveals that an enhancer can recruit cohesin to create contact domains, engage CTCF sites and activate distant genes
Rinzema, N. J., Sofiadis, K., Tjalsma, S. J. D., Verstegen, M. J. A. M., Oz, Y., Valdes-Quezada, C., Felder, A-K., Filipovska, T., van der Elst, S., de Andrade Dos Ramos, Z., Han, R., Krijger, P. H. L. & de Laat, W., Jun 2022, In: Nature Structural & Molecular Biology. 29, 6, p. 563-574 12 p.Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open Access -
Current challenges in understanding the role of enhancers in disease
Zaugg, J. B., Sahlén, P., Andersson, R., Alberich-Jorda, M., de Laat, W., Deplancke, B., Ferrer, J., Mandrup, S., Natoli, G., Plewczynski, D., Rada-Iglesias, A. & Spicuglia, S., 08 Dec 2022, (E-pub ahead of print) In: Nature Structural & Molecular Biology.Research output: Contribution to journal/periodical › Book/Film/Article review › Scientific
Open Access -
Role of the cellular factor CTCF in the regulation of bovine leukemia virus latency and three-dimensional chromatin organization
Bellefroid, M., Rodari, A., Galais, M., Krijger, P. H. L., Tjalsma, S. J. D., Nestola, L., Plant, E., Vos, E. S. M., Cristinelli, S., Van Driessche, B., Vanhulle, C., Ait-Ammar, A., Burny, A., Ciuffi, A., de Laat, W. & Van Lint, C., 08 Apr 2022, In: Nucleic Acids Research. 50, 6, p. 3190-3202 13 p.Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open Access -
A public-private partnership model for COVID-19 diagnostics
Krijger, P. H. L., Hoek, T. A., Boersma, S., Donders, L. I. P. M., Broeders, M. M. C., Pieterse, M., Toonen, P. W., Logister, I., Verhagen, B. M. P., Verstegen, M. J. A. M., van Ravesteyn, T. W., Roymans, R. J. T. M., Mattiroli, F., Vandesompele, J., Nijhuis, M., Meijer, S., van Weert, A., Dekker, E., Dom, F. J., Ruijtenbeek, R., & 5 others, Oct 2021, In: Nature Biotechnology. 39, 10, p. 1182-1184 3 p.Research output: Contribution to journal/periodical › Article › Scientific › peer-review
Open Access -
Interplay between CTCF boundaries and a super enhancer controls cohesin extrusion trajectories and gene expression
Vos, E. S. M., Valdes-Quezada, C., Huang, Y., Allahyar, A., Verstegen, M. J. A. M., Felder, A-K., van der Vegt, F., Uijttewaal, E. C. H., Krijger, P. H. L. & de Laat, W., 05 Aug 2021, In: Molecular Cell. 81, 15, p. 3082-3095.e6Research output: Contribution to journal/periodical › Article › Scientific › peer-review