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  • Alexander van Oudenaarden
2020

Sequencing metabolically labeled transcripts in single cells reveals mRNA turnover strategies

Battich, N., Beumer, J., de Barbanson, B., Krenning, L., Baron, C. S., Tanenbaum, M. E., Clevers, H. & van Oudenaarden, A., 06 Mar 2020, In : Science. 367, 6482, p. 1151-1156 6 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Snake Venom Gland Organoids

Post, Y., Puschhof, J., Beumer, J., Kerkkamp, H. M., de Bakker, M. A. G., Slagboom, J., de Barbanson, B., Wevers, N. R., Spijkers, X. M., Olivier, T., Kazandjian, T. D., Ainsworth, S., Iglesias, C. L., van de Wetering, W. J., Heinz, M. C., van Ineveld, R. L., van Kleef, R. G. D. M., Begthel, H., Korving, J., Bar-Ephraim, Y. E. & 11 others, Getreuer, W., Rios, A. C., Westerink, R. H. S., Snippert, H. J. G., van Oudenaarden, A., Peters, P. J., Vonk, F. J., Kool, J., Richardson, M. K., Casewell, N. R. & Clevers, H., 23 Jan 2020, In : Cell. 180, 2, p. 233-247.e21

Research output: Contribution to journal/periodicalArticleScientificpeer-review

2019

An organoid platform for ovarian cancer captures intra- and interpatient heterogeneity

Kopper, O., de Witte, C. J., Lõhmussaar, K., Valle-Inclan, J. E., Hami, N., Kester, L., Balgobind, A. V., Korving, J., Proost, N., Begthel, H., van Wijk, L. M., Revilla, S. A., Theeuwsen, R., van de Ven, M., van Roosmalen, M. J., Ponsioen, B., Ho, V. W. H., Neel, B. G., Bosse, T., Gaarenstroom, K. N. & 11 others, Vrieling, H., Vreeswijk, M. P. G., van Diest, P. J., Witteveen, P. O., Jonges, T., Bos, J. L., van Oudenaarden, A., Zweemer, R. P., Snippert, H. J. G., Kloosterman, W. P. & Clevers, H., May 2019, In : Nature Medicine. 25, 5, p. 838-849 12 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

A transcriptomic roadmap to α- and β-cell differentiation in the embryonic pancreas

van Gurp, L., Muraro, M. J., Dielen, T., Seneby, L., Dharmadhikari, G., Gradwohl, G., van Oudenaarden, A. & de Koning, E. J. P., 24 Jun 2019, In : Development (Cambridge). 146, 12

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Cell Type Purification by Single-Cell Transcriptome-Trained Sorting

Baron, C. S., Barve, A., Muraro, M. J., van der Linden, R., Dharmadhikari, G., Lyubimova, A., de Koning, E. J. P. & van Oudenaarden, A., 03 Oct 2019, In : Cell. 179, 2, p. 527-542.e19

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

Combined quantification of intracellular (phospho-)proteins and transcriptomics from fixed single cells

Gerlach, J. P., van Buggenum, J. A. G., Tanis, S. E. J., Hogeweg, M., Heuts, B. M. H., Muraro, M. J., Elze, L., Rivello, F., Rakszewska, A., van Oudenaarden, A., Huck, W. T. S., Stunnenberg, H. G. & Mulder, K. W., 06 Feb 2019, In : Scientific Reports. 9, 1, p. 1469

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

Correction: Neuromesodermal progenitors are a conserved source of spinal cord with divergent growth dynamics (doi: 10.1242/dev.166728)

Attardi, A., Fulton, T., Florescu, M., Shah, G., Muresan, L., Lenz, M. O., Lancaster, C., Huisken, J., van Oudenaarden, A. & Steventon, B., 22 Jan 2019, In : Development (Cambridge). 146, 2

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

Enteroendocrine and tuft cells support Lgr5 stem cells on Paneth cell depletion

van Es, J. H., Wiebrands, K., López-Iglesias, C., van de Wetering, M., Zeinstra, L., van den Born, M., Korving, J., Sasaki, N., Peters, P. J., van Oudenaarden, A. & Clevers, H., 16 Dec 2019, In : Proceedings of the National Academy of Sciences of the United States of America.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Long-term expanding human airway organoids for disease modeling

Sachs, N., Papaspyropoulos, A., Zomer-van Ommen, D. D., Heo, I., Böttinger, L., Klay, D., Weeber, F., Huelsz-Prince, G., Iakobachvili, N., Amatngalim, G. D., de Ligt, J., van Hoeck, A., Proost, N., Viveen, M. C., Lyubimova, A., Teeven, L., Derakhshan, S., Korving, J., Begthel, H., Dekkers, J. F. & 28 others, Kumawat, K., Ramos, E., van Oosterhout, M. F., Offerhaus, G. J., Wiener, D. J., Olimpio, E. P., Dijkstra, K. K., Smit, E. F., van der Linden, M., Jaksani, S., van de Ven, M., Jonkers, J., Rios, A. C., Voest, E. E., van Moorsel, C. H., van der Ent, C. K., Cuppen, E., van Oudenaarden, A., Coenjaerts, F. E., Meyaard, L., Bont, L. J., Peters, P. J., Tans, S. J., van Zon, J. S., Boj, S. F., Vries, R. G., Beekman, J. M. & Clevers, H., 15 Feb 2019, In : EMBO Journal. 38, 4

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids

Bolhaqueiro, A. C. F., Ponsioen, B., Bakker, B., Klaasen, S. J., Kucukkose, E., van Jaarsveld, R. H., Vivié, J., Verlaan-Klink, I., Hami, N., Spierings, D. C. J., Sasaki, N., Dutta, D., Boj, S. F., Vries, R. G. J., Lansdorp, P. M., van de Wetering, M., van Oudenaarden, A., Clevers, H., Kranenburg, O., Foijer, F. & 2 others, Snippert, H. J. G. & Kops, G. J. P. L., May 2019, In : Nature Genetics. 51, 5, p. 824-834 11 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Oral mucosal organoids as a potential platform for personalized cancer therapy

Driehuis, E., Kolders, S., Spelier, S., Lohmussaar, K., Willems, S. M., Devriese, L. A., de Bree, R., de Ruiter, E. J., Korving, J., Begthel, H., Van Es, J. H., Geurts, V., He, G-W., van Jaarsveld, R. H., Oka, R., Muraro, M. J., Vivie, J., Zandvliet, M. M. J. M., Hendrickx, A. P. A., Iakobachvili, N. & 8 others, Sridevi, P., Kranenburg, O., van Boxtel, R., Kops, G. J. P. L., Tuveson, D. A., Peters, P. J., van Oudenaarden, A. & Clevers, H., Jul 2019, In : Cancer Discovery.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Single-Cell Analysis of the Liver Epithelium Reveals Dynamic Heterogeneity and an Essential Role for YAP in Homeostasis and Regeneration

Pepe-Mooney, B. J., Dill, M. T., Alemany, A., Ordovas-Montanes, J., Matsushita, Y., Rao, A., Sen, A., Miyazaki, M., Anakk, S., Dawson, P. A., Ono, N., Shalek, A. K., van Oudenaarden, A. & Camargo, F. D., 03 Jul 2019, In : Cell Stem Cell. 25, 1, p. 23-38.e8

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart

Honkoop, H., de Bakker, D. E., Aharonov, A., Kruse, F., Shakked, A., Nguyen, P. D., de Heus, C., Garric, L., Muraro, M. J., Shoffner, A., Tessadori, F., Peterson, J. C., Noort, W., Bertozzi, A., Weidinger, G., Posthuma, G., Grun, D., van der Laarse, W. J., Klumperman, J., Jaspers, R. T. & 4 others, Poss, K. D., van Oudenaarden, A., Tzahor, E. & Bakkers, J., 23 Dec 2019, In : eLife. 8

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

Spindle checkpoint silencing at kinetochores with submaximal microtubule occupancy

Etemad, B., Vertesy, A., Kuijt, T. E. F., Sacristan, C., van Oudenaarden, A. & Kops, G. J. P. L., 17 Jun 2019, In : Journal of Cell Science. 132, 12

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

Unravelling cellular relationships during development and regeneration using genetic lineage tracing

Baron, C. S. & van Oudenaarden, A., Dec 2019, In : Nature reviews. Molecular cell biology. 20, 12, p. 753-765 13 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

2018

A Caenorhabditis elegans protein with a PRDM9-like SET domain localizes to chromatin-associated foci and promotes spermatocyte gene expression, sperm production and fertility

Engert, C. G., Droste, R., van Oudenaarden, A. & Horvitz, H. R., Apr 2018, In : PLoS Genetics. 14, 4, p. e1007295

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

Blastocyst-like structures generated solely from stem cells

Rivron, N. C., Frias-Aldeguer, J., Vrij, E. J., Boisset, J-C., Korving, J., Vivié, J., Truckenmüller, R. K., van Oudenaarden, A., van Blitterswijk, C. A. & Geijsen, N., May 2018, In : Nature. 557, 7703, p. 106-111 6 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Expansion of Adult Human Pancreatic Tissue Yields Organoids Harboring Progenitor Cells with Endocrine Differentiation Potential

Loomans, C. J. M., Williams Giuliani, N., Balak, J., Ringnalda, F. C., van Gurp, L., Huch, M., Boj, S. F., Sato, T., Kester, L., de Sousa Lopes, S. M. C., Roost, M. S., Bonner-Weir, S., Engelse, M. A., Rabelink, T. J., Heimberg, H., Vries, R. G. J., van Oudenaarden, A., Carlotti, F., Clevers, H. & de Koning, E. J. P., 13 Mar 2018, In : Stem Cell Reports. 10, 3, p. 712-724 13 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

Mapping the physical network of cellular interactions

Boisset, J-C., Vivié, J., Grün, D., Muraro, M. J., Lyubimova, A. & van Oudenaarden, A., Jul 2018, In : Nature Methods. 15, 7, p. 547-553 7 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Neuromesodermal progenitors are a conserved source of spinal cord with divergent growth dynamics

Attardi, A., Fulton, T., Florescu, M., Shah, G., Muresan, L., Lenz, M. O., Lancaster, C., Huisken, J., van Oudenaarden, A. & Steventon, B., 09 Nov 2018, In : Development (Cambridge). 145, 21

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

Parental haplotype-specific single-cell transcriptomics reveal incomplete epigenetic reprogramming in human female germ cells

Vértesy, Á., Arindrarto, W., Roost, M. S., Reinius, B., Torrens-Juaneda, V., Bialecka, M., Moustakas, I., Ariyurek, Y., Kuijk, E., Mei, H., Sandberg, R., van Oudenaarden, A. & Chuva de Sousa Lopes, S. M., 14 May 2018, In : Nature Communications. 9, 1, p. 1873

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

Single-cell analysis reveals that stochasticity and paracrine signaling control interferon-alpha production by plasmacytoid dendritic cells

Wimmers, F., Subedi, N., van Buuringen, N., Heister, D., Vivié, J., Beeren-Reinieren, I., Woestenenk, R., Dolstra, H., Piruska, A., Jacobs, J. F. M., van Oudenaarden, A., Figdor, C. G., Huck, W. T. S., de Vries, I. J. M. & Tel, J., 20 Aug 2018, In : Nature Communications. 9, 1, p. 3317

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

Single-Cell Sequencing of the Healthy and Diseased Heart Reveals Cytoskeleton-Associated Protein 4 as a New Modulator of Fibroblasts Activation

Gladka, M. M., Molenaar, B., de Ruiter, H., van der Elst, S., Tsui, H., Versteeg, D., Lacraz, G. P. A., Huibers, M. M. H., van Oudenaarden, A. & van Rooij, E., 10 Jul 2018, In : Circulation. 138, 2, p. 166-180 15 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

Single-Cell Transcriptomics Meets Lineage Tracing

Kester, L. & van Oudenaarden, A., 02 Aug 2018, In : Cell Stem Cell. 23, 2, p. 166-179 14 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Single-cell transcriptomics reveal the dynamic of haematopoietic stem cell production in the aorta

Baron, C. S., Kester, L., Klaus, A., Boisset, J-C., Thambyrajah, R., Yvernogeau, L., Kouskoff, V., Lacaud, G., van Oudenaarden, A. & Robin, C., 28 Jun 2018, In : Nature Communications. 9, 1, p. 2517

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

Spatial Transcriptomics of C. elegans Males and Hermaphrodites Identifies Sex-Specific Differences in Gene Expression Patterns

Ebbing, A., Vértesy, Á., Betist, M. C., Spanjaard, B., Junker, J. P., Berezikov, E., van Oudenaarden, A. & Korswagen, H. C., 17 Dec 2018, In : Developmental Cell. 47, 6, p. 801-813.e6

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Tdrd6a Regulates the Aggregation of Buc into Functional Subcellular Compartments that Drive Germ Cell Specification

Roovers, E. F., Kaaij, L. J. T., Redl, S., Bronkhorst, A. W., Wiebrands, K., de Jesus Domingues, A. M., Huang, H-Y., Han, C-T., Riemer, S., Dosch, R., Salvenmoser, W., Grün, D., Butter, F., van Oudenaarden, A. & Ketting, R. F., 06 Aug 2018, In : Developmental Cell. 46, 3, p. 285-301.e9

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

The Majority of CD45 Ter119 CD31 Bone Marrow Cell Fraction Is of Hematopoietic Origin and Contains Erythroid and Lymphoid Progenitors

Boulais, P. E., Mizoguchi, T., Zimmerman, S., Nakahara, F., Vivié, J., Mar, J. C., van Oudenaarden, A. & Frenette, P. S., 16 Oct 2018, In : Immunity. 49, 4, p. 627-639.e6

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Troy+ brain stem cells cycle through quiescence and regulate their number by sensing niche occupancy

Basak, O., Krieger, T. G., Muraro, M. J., Wiebrands, K., Stange, D. E., Frias-Aldeguer, J., Rivron, N. C., van de Wetering, M., van Es, J. H., van Oudenaarden, A., Simons, B. D. & Clevers, H., 23 Jan 2018, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 4, p. E610-E619

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

Whole-organism clone tracing using single-cell sequencing

Alemany, A., Florescu, M., Baron, C. S., Peterson-Maduro, J. & van Oudenaarden, A., 05 Apr 2018, In : Nature. 556, 7699, p. 108-112 5 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

2017

A Single-Cell RNA Sequencing Study Reveals Cellular and Molecular Dynamics of the Hippocampal Neurogenic Niche

Artegiani, B., Lyubimova, A., Muraro, M. J., van Es, J. H., van Oudenaarden, A. & Clevers, H., 12 Dec 2017, In : Cell Reports. 21, 11, p. 3271-3284 14 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

Celebrating 100 years of Developmental Biology at the Hubrecht Institute

den Hertog, J. (Guest ed.) & van Oudenaarden, A. (Guest ed.), 15 Aug 2017, In : Developmental Biology. 428, 2

Research output: Contribution to journal/periodicalSpecial issue (editorship)Scientific

Celebrating 100 years of Developmental Biology at the Hubrecht Institute

den Hertog, J. & van Oudenaarden, A., 2017, In : Developmental Biology. 428, 2, p. 259-260

Research output: Contribution to journal/periodicalArticlePopularizing

Circadian networks in human embryonic stem cell-derived cardiomyocytes

Dierickx, P., Vermunt, M. W., Muraro, M. J., Creyghton, M. P., Doevendans, P. A., van Oudenaarden, A., Geijsen, N. & Van Laake, L. W., Jul 2017, In : EMBO Reports. 18, 7, p. 1199-1212 14 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Dynamics of lineage commitment revealed by single-cell transcriptomics of differentiating embryonic stem cells

Semrau, S., Goldmann, J. E., Soumillon, M., Mikkelsen, T. S., Jaenisch, R. & van Oudenaarden, A., 23 Oct 2017, In : Nature Communications. 8, 1, p. 1096

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

Identity and dynamics of mammary stem cells during branching morphogenesis

Scheele, C. L. G. J., Hannezo, E., Muraro, M. J., Zomer, A., Langedijk, N. S. M., van Oudenaarden, A., Simons, B. D. & van Rheenen, J., 16 Feb 2017, In : Nature. 542, 7641, p. 313-317 5 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Science Forum: The Human Cell Atlas

Regev, A., Teichmann, S. A., Lander, E. S., Amit, I., Benoist, C., Birney, E., Bodenmiller, B., Campbell, P. J., Carninci, P., Clatworthy, M., Clevers, H., Deplancke, B., Dunham, I., Eberwine, J., Eils, R., Enard, W., Farmer, A. D., Fugger, L., Göttgens, B., Hacohen, N. & 30 others, Haniffa, M., Hemberg, M., Kim, S. K., Klenerman, P., Kriegstein, A., Lein, E., Linnarsson, S., Lundberg, E., Lundeberg, J., Majumder, P., Marioni, J. C., Merad, M., Mhlanga, M., Nawijn, M., Netea, M. G., Nolan, G., Pe'er, D., Phillipakis, A., Ponting, C. P., Quake, S. R., Reik, W., Rozenblatt-Rosen, O., Sanes, J. R., Satija, R., Schumacher, T. N., Shalek, A. K., Shapiro, E., Sharma, P., Shin, J. W. & van Oudenaarden, A., 05 Dec 2017, In : eLife. 6

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

Single-cell sequencing reveals dissociation-induced gene expression in tissue subpopulations

van den Brink, S. C., Sage, F., Vértesy, Á., Spanjaard, B., Peterson-Maduro, J., Baron, C. S., Robin, C. & van Oudenaarden, A., 29 Sep 2017, In : Nature Methods. 14, 10, p. 935-936 2 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

The Human Cell Atlas

05 Dec 2017, In : eLife. 6, e27041.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

Tomo-Seq Identifies SOX9 as a Key Regulator of Cardiac Fibrosis During Ischemic Injury

Lacraz, G. P. A., Junker, J. P., Gladka, M. M., Molenaar, B., Scholman, K. T., Vigil-Garcia, M., Versteeg, D., de Ruiter, H., Vermunt, M. W., Creyghton, M. P., Huibers, M. M. H., de Jonge, N., van Oudenaarden, A. & van Rooij, E., 10 Oct 2017, In : Circulation. 136, 15, p. 1396-1409 14 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

2016

A Single-Cell Transcriptome Atlas of the Human Pancreas

Muraro, M. J., Dharmadhikari, G., Grün, D., Groen, N., Dielen, T., Jansen, E., van Gurp, L., Engelse, M. A., Carlotti, F., de Koning, E. J. P. & van Oudenaarden, A., 26 Oct 2016, In : Cell Systems. 3, 4, p. 385-394.e3

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

Cdx and T Brachyury Co-activate Growth Signaling in the Embryonic Axial Progenitor Niche

Amin, S., Neijts, R., Simmini, S., van Rooijen, C., Tan, S. C., Kester, L., van Oudenaarden, A., Creyghton, M. P. & Deschamps, J., 20 Dec 2016, In : Cell Reports. 17, 12, p. 3165-3177 13 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

De Novo Prediction of Stem Cell Identity using Single-Cell Transcriptome Data

Grün, D., Muraro, M. J., Boisset, J-C., Wiebrands, K., Lyubimova, A., Dharmadhikari, G., van den Born, M., van Es, J., Jansen, E., Clevers, H., de Koning, E. J. P. & van Oudenaarden, A., 21 Jun 2016, In : Cell Stem Cell.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq

Jaitin, D. A., Weiner, A., Yofe, I., Lara-Astiaso, D., Keren-Shaul, H., David, E., Salame, T. M., Tanay, A., van Oudenaarden, A. & Amit, I., 15 Dec 2016, In : Cell. 167, 7, p. 1883-1896.e15

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Induced Quiescence of Lgr5+ Stem Cells in Intestinal Organoids Enables Differentiation of Hormone-Producing Enteroendocrine Cells

Basak, O., Beumer, J., Wiebrands, K., Seno, H., van Oudenaarden, A. & Clevers, H., 17 Nov 2016, In : Cell Stem Cell.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Patched receptors sense, interpret and establish an epidermal Hedgehog signalling gradient

Adolphe, C., Junker, J. P., Lyubimova, A., van Oudenaarden, A. & Wainwright, B., 04 Aug 2016, In : Journal of Investigative Dermatology.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Plasticity between Epithelial and Mesenchymal States Unlinks EMT from Metastasis-Enhancing Stem Cell Capacity

Beerling, E., Seinstra, D., de Wit, E., Kester, L., van der Velden, D., Maynard, C., Schäfer, R., van Diest, P., Voest, E., van Oudenaarden, A., Vrisekoop, N. & van Rheenen, J., 03 Mar 2016, In : Cell Reports. 14, 10, p. 2281-8 8 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

Reg4+ deep crypt secretory cells function as epithelial niche for Lgr5+ stem cells in colon

Sasaki, N., Sachs, N., Wiebrands, K., Ellenbroek, S. I. J., Fumagalli, A., Lyubimova, A., Begthel, H., van den Born, M., van Es, J. H., Karthaus, W. R., Li, V. S. W., López-Iglesias, C., Peters, P. J., van Rheenen, J., van Oudenaarden, A. & Clevers, H., 29 Aug 2016, In : Proceedings of the National Academy of Sciences of the United States of America.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

Replacement of Lost Lgr5-Positive Stem Cells through Plasticity of Their Enterocyte-Lineage Daughters

Tetteh, P. W., Basak, O., Farin, H. F., Wiebrands, K., Kretzschmar, K., Begthel, H., van den Born, M., Korving, J., de Sauvage, F., van Es, J. H., van Oudenaarden, A. & Clevers, H., 04 Feb 2016, In : Cell Stem Cell. 18, 2, p. 203-13 11 p.

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Open Access

Single-cell 5hmC sequencing reveals chromosome-wide cell-to-cell variability and enables lineage reconstruction

Mooijman, D., Dey, S. S., Boisset, J-C., Crosetto, N. & van Oudenaarden, A., 27 Jun 2016, In : Nature Biotechnology.

Research output: Contribution to journal/periodicalArticleScientificpeer-review