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• 2020

  After-Effects of Time-Restricted Feeding on Whole-Body Metabolism and Gene Expression in Four Different Peripheral Tissues

  de Goede, P., Hellings, T. P., Coopmans, T. V., Ritsema, W. I. G. R. & Kalsbeek, A., 2020, In: Obesity. 28, Suppl. 1, p. S68-S80

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File

  • Fasting
  • Light
  • Gene Expression
  • Skeletal Muscle
  • Animals
  20 Downloads (Pure)

• Behavioral Circadian Timing System Disruptors and Incident Type 2 Diabetes in a Nonshift Working Multi-Ethnic Population

  Muilwijk, M., Stenvers, D. J., Nicolaou, M., Kalsbeek, A. & van Valkengoed, I. G. M., 2020, In: Obesity. 28, Suppl. 1, p. S55-S62

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File

  • Circadian Clocks
  • Type 2 Diabetes Mellitus
  • Sleep
  • Population
  • Snacks
  101 Downloads (Pure)

• Biphasic glucocorticoid rhythm in one month old infants: reflection of a developing HPA-axis?

  Hollanders, J. J., van der Voorn, B., de Goede, P., Toorop, A. A., Dijkstra, L. R., Honig, A., Rotteveel, J., Dolman, K. M., Kalsbeek, A. & Finken, M. J. J., 2020, In: The Journal of clinical endocrinology and metabolism. 105, dgz089.

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File

  • Hypothalamus
  • Cortisone
  • Glucocorticoids
  • Hydrocortisone
  • 4-amino-4'-hydroxylaminodiphenylsulfone
  61 Downloads (Pure)

• Deficiency of the Circadian Clock Gene Bmal1 Reduces Microglial Immunometabolism

  Wang, X-L., Wolff, S. E. C., Korpel, N., Milanova, I., Sandu, C., Rensen, P. C. N., Kooijman, S., Cassel, J-C., Kalsbeek, A., Boutillier, A-L. & Yi, C-X., 2020, In: Frontiers in Immunology. 11, p. 586399

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File

  • Circadian Clocks
  • Muscles
  • Microglia
  • Brain
  • Genes
  48 Downloads (Pure)

• How the COVID-19 pandemic highlights the necessity of animal research

  Genzel, L., Adan, R., Berns, A., van den Beucken, J., Blokland, A., Boddeke, E. H. W. G. M., Bogers, W. M., Bontrop, R., Bulthuis, R., Bousema, T., Clevers, H., Coenen, T. C. J. J., Dam, A-M. V., Deen, P. M. T., van Dijk, K. W., Eggen, B. J. L., Elgersma, Y., Erdogan, I., Englitz, B., Fentener van Vlissingen, J. M. & 62 others, la Fleur, S., Fouchier, R., Fitzsimons, C. P., Frieling, W., Haagmans, B., Heesters, B. A., Henckens, M., Herfst, S., Hol, E., van den Hove, D., de Jonge, M. I., Jonkers, J., Joosten, L. A. B., Kalsbeek, A., Kamermans, M., Kampinga, H. H., Kas, M. J., Keijer, J., Kersten, S., Kiliaan, A. J., Kooij, T. W. A., Kooijman, S., Koopman, W. J. H., Korosi, A., Krugers, H. J., Kuiken, T., Kushner, S. A., Langermans, J. A. M., Lesscher, H., Lucassen, P. J., Lutgens, E., Netea, M. G., Noldus, L. P. J. J., van der Meer, J. W. M., Meye, F. J., Mul, J. D., van Oers, K., Olivier, J. D. A., Pasterkamp, R. J., Philippens, I. H. C. H. M., Prickaerts, J., Pullox, B., Rensen, P. C. N., van Rheenen, J., van Rij, R. P., Ritsma, L., Rockx, B. H. G., Roozendaal, B., van Schothorst, E. M., Stittelaar, K., Stockhofe, N., Swaab, D. F., de Swart, R. L., Vanderschuren, L. J. M. J., de Vries, T., de Vrij, F., van Wezel, R., Wierenga, C. J., Wiesmann, M., Willuhn, I., de Zeeuw, C. I. & Homberg, J. R., 10 Aug 2020, In: Current Biology. 30, 18, p. R1014-R1018 5 p.

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

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  • animal research
  • pandemic
  • Pandemics
  • Animals
  • animals
  62 Downloads (Pure)

• Metabolic Effects of Light at Night are Time- and Wavelength-Dependent in Rats

  Masís-Vargas, A., Ritsema, W. I. G. R., Mendoza, J. & Kalsbeek, A., 2020, In: Obesity. 28 Suppl 1, p. S114-S125

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File

  • Methyl Green
  • Light
  • Energy Metabolism
  • Locomotion
  • Liver
  49 Downloads (Pure)

• Metabolic Implications of Exposure to Light at Night: Lessons from Animal and Human Studies

  Fleury, G., Masís-Vargas, A. & Kalsbeek, A., 2020, In: Obesity. 28 Suppl 1, p. S18-S28

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File

  • Light
  • Animals
  • Overweight
  • melanopsin
  • Biological Clocks
  28 Downloads (Pure)

• Muscle Clocks and Diabetes

  Kalsbeek, A. & Schrauwen, P., 2020, In: Obesity. 28 Suppl 1, p. S5

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File
  11 Downloads (Pure)

• Regulation of type 3 deiodinase in rodent liver and adipose tissue during fasting

  de Vries, E. M., van Beeren, H. C., van Wijk, A. C. W. A., Kalsbeek, A., Romijn, J. A., Fliers, E. & Boelen, A., 2020, In: Endocrine connections. 9, p. 552-562

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File

  • Iodide Peroxidase
  • constitutive androstane receptor
  • Adipose Tissue
  • Rodentia
  • Fasting
  190 Downloads (Pure)

• RFRP3 increases food intake in a sex-dependent manner in the seasonal hamster Phodopus sungorus

  Cázarez-Márquez, F., Laran-Chich, M-P., Klosen, P., Kalsbeek, A. & Simonneaux, V., 2020, In: Journal of Neuroendocrinology. 32, p. e12845

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File

  • RFamide peptide
  • Phodopus
  • Cricetinae
  • Eating
  • 3-nitro-2-pyridinesulfenyl
  16 Downloads (Pure)

• Synergistic Effect of Feeding Time and Diet on Hepatic Steatosis and Gene Expression in Male Wistar Rats

  Oosterman, J. E., Koekkoek, L. L., Foppen, E., Unmehopa, U. A., Eggels, L., Verheij, J., Fliers, E., la Fleur, S. E. & Kalsbeek, A., 2020, In: Obesity. 28, Suppl. 1, p. S81-S92

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File

  • Sugars
  • Wistar Rats
  • Fats
  • Diet
  • Light
  19 Downloads (Pure)

• The Circadian Clock, Shift Work, and Tissue-Specific Insulin Resistance

  Oosterman, J. E., Wopereis, S. & Kalsbeek, A., 2020, In: Endocrinology. 161, 12, bqaa180.

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File

  • Circadian Clocks
  • Biological Clocks
  • Insulin Resistance
  • Eating
  • Homeostasis
  17 Downloads (Pure)

• The Effect of Rev-erbα Agonist SR9011 on the Immune Response and Cell Metabolism of Microglia

  Wolff, S. E. C., Wang, X-L., Jiao, H., Sun, J., Kalsbeek, A., Yi, C-X. & Gao, Y., 2020, In: Frontiers in Immunology. 11, p. 550145

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File

  • SR9011
  • Microglia
  • Cytokines
  • Metabolic Diseases
  • Gene Expression
  285 Downloads (Pure)

• The impact of antidiabetic treatment on human hypothalamic infundibular neurons and microglia

  Kalsbeek, M. J., Wolff, S. E., Korpel, N. L., la Fleur, S. E., Romijn, J. A., Fliers, E., Kalsbeek, A., Swaab, D. F., Huitinga, I., Hol, E. M. & Yi, C-X., 2020, In: JCI insight. 5, 16, 133868.

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File

  • Microglia
  • Hypoglycemic Agents
  • Type 2 Diabetes Mellitus
  • Neurons
  • Neuropeptide Y
  66 Downloads (Pure)
• 2019

  Blue light at night acutely impairs glucose tolerance and increases sugar intake in the diurnal rodent Arvicanthis ansorgei in a sex-dependent manner

  Masís-Vargas, A., Hicks, D., Kalsbeek, A. & Mendoza, J., 2019, In: Physiological Reports. 7, 20, p. e14257

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File

  • Sugars
  • Rodentia
  • Light
  • Glucose
  • Sucrose
  77 Downloads (Pure)

• Circadian clocks and insulin resistance

  Jan Stenvers, D., Scheer, F. A. J. L., Schrauwen, P., la Fleur, S. E. & Kalsbeek, A., 03 Jan 2019, In: Nature Reviews Endocrinology. 15, p. 75-89

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File

  • Circadian Clocks
  • Insulin Resistance
  • Glucose
  • Jet Lag Syndrome
  • Sleep
  1443 Downloads (Pure)

• Corrigendum to "Deficiency of leptin receptor in myeloid cells disrupts hypothalamic metabolic circuits and causes body weight increase" [Molecular Metabolism 7 (2018) 155-160]

  Gao, Y., Vidal-Itriago, A., Milanova, I., Korpel, N. L., Kalsbeek, M. J., Tom, R. Z., Kalsbeek, A., Hofmann, S. M. & Yi, C. X., Feb 2019, In: Molecular Metabolism. 20, p. 205

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

• Diet-Induced Obesity Disturbs Microglial Immunometabolism in a Time-of-Day Manner

  Milanova, I. V., Kalsbeek, M. J. T., Wang, X-L., Korpel, N. L., Stenvers, D. J., Wolff, S. E. C., de Goede, P., Heijboer, A. C., Fliers, E., la Fleur, S. E., Kalsbeek, A. & Yi, C-X., 2019, In: Frontiers in Endocrinology. 10, p. 424

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  • High Fat Diet
  • Microglia
  • Obesity
  • Diet
  • Periodicity

• Diurnal rhythms in the white adipose tissue transcriptome are disturbed in obese individuals with type 2 diabetes compared with lean control individuals

  Stenvers, D. J., Jongejan, A., Atiqi, S., Vreijling, J. P., Limonard, E. J., Endert, E., Baas, F., Moerland, P. D., Fliers, E., Kalsbeek, A. & Bisschop, P. H., Jan 2019, In: Diabetologia. 62, p. 704-716

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  File

  • White Adipose Tissue
  • Circadian Rhythm
  • Transcriptome
  • Type 2 Diabetes Mellitus
  • Eukaryotic Initiation Factor-2
  25 Downloads (Pure)

• Effects of Light-at-Night on the Rat Liver - A Role for the Autonomic Nervous System

  Opperhuizen, A-L., Foppen, E., Jonker, M., Wackers, P., van Faassen, M., van Weeghel, M., van Kerkhof, L., Fliers, E. & Kalsbeek, A., 10 Apr 2019, In: Frontiers in Neuroscience. 13, p. 647

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File

  • Autonomic Nervous System
  • Light
  • Liver
  • Transcriptome
  • Denervation
  66 Downloads (Pure)

• Kisspeptin and RFRP3 modulate body mass in Phodopus sungorus via two different neuroendocrine pathways

  Cázarez-Márquez, F., Milesi, S., Laran-Chich, M-P., Klosen, P., Kalsbeek, A. & Simonneaux, V., 2019, In: Journal of Neuroendocrinology. 31, p. e12710

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  File

  • Phodopus
  • Kisspeptins
  • Body Weight
  • Reproduction
  • Pro-Opiomelanocortin
  46 Downloads (Pure)

• Loss of arginine vasopressin- and vasoactive intestinal polypeptide-containing neurons and glial cells in the suprachiasmatic nucleus of individuals with type 2 diabetes

  Hogenboom, R., Kalsbeek, M. J., Korpel, N. L., de Goede, P., Koenen, M., Buijs, R. M., Romijn, J. A., Swaab, D. F., Kalsbeek, A. & Yi, C-X., 05 May 2019, In: Diabetologia. 62, p. 2088-2093

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  • Suprachiasmatic Nucleus Neurons
  • Suprachiasmatic Nucleus
  • Arginine Vasopressin
  • Vasoactive Intestinal Peptide
  • Neuroglia

• Neuropeptide changes in the suprachiasmatic nucleus are associated with the development of hypertension

  Yilmaz, A., Buijs, F. N., Kalsbeek, A. & Buijs, R. M., 2019, In: Chronobiology International. 36, p. 1072-1087 16 p.

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  File

  • Suprachiasmatic Nucleus
  • Neuropeptides
  • Vasoactive Intestinal Peptide
  • Hypertension
  • Inbred SHR Rats
  40 Downloads (Pure)

• Potential Role for the Gut Microbiota in Modulating Host Circadian Rhythms and Metabolic Health

  Parkar, S. G., Kalsbeek, A. & Cheeseman, J. F., Jan 2019, In: Microorganisms. 7, 2, E 41.

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File

  • Circadian Rhythm
  • Gastrointestinal Microbiome
  • Sleep
  • Butyrates
  • Microbiota
  166 Downloads (Pure)

• Regulation of Brain DNA Methylation Factors and of the Orexinergic System by Cocaine and Food Self-Administration

  Saad, L., Sartori, M., Pol Bodetto, S., Romieu, P., Kalsbeek, A., Zwiller, J. & Anglard, P., Jan 2019, In: Molecular Neurobiology. 56, p. 5315-5331

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  File

  • Self Administration
  • Putamen
  • DNA Methylation
  • Cocaine
  • Orexins
  32 Downloads (Pure)

• Restoring the autonomic balance to reduce liver steatosis

  Bruinstroop, E., Fliers, E. & Kalsbeek, A., Jun 2019, In: The Journal of physiology. 597, 18, p. 4683-4684 2 p.

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

• Social Jet-Lag in Tertiary Students Following a Modern Curriculum with Few Time-Tabled Contact Hours: A Pilot Study

  Leenaars, C. H. C., Lucassen, M. F. G., Borger, N., Houben, E. & Kalsbeek, A., Sep 2019, In: Clocks & sleep. 1, 3, p. 306-318 13 p.

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  • Jet Lag Syndrome
  • Strigiformes
  • Curriculum
  • Sleep
  • Problem-Based Learning

• The Iminosugar AMP-DNM Improves Satiety and Activates Brown Adipose Tissue Through GLP1

  Moro Chao, D. H., Wang, Y., Foppen, E., Ottenhoff, R., van Roomen, C., Parlevliet, E. T., van Eijk, M., Verhoek, M., Boot, R., Marques, A. R., Scheij, S., Mirzaian, M., Kooijman, S., Jansen, K., Wang, D., Mergen, C., Seeley, R. J., Tschöp, M. H., Overkleeft, H., Rensen, P. C. N. & 3 others, Kalsbeek, A., Aerts, J. M. F. G. & Yi, C-X., 2019, In: Diabetes. 68, p. 2223-2234

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  File

  • N-(5-adamantane-1-yl-methoxy-pentyl)deoxynojirimycin
  • Brown Adipose Tissue
  • Glucagon-Like Peptide 1
  • exendin receptor
  • Rodentia
  20 Downloads (Pure)

• Time-Restricted Feeding Improves Glucose Tolerance in Rats, but Only When in Line With the Circadian Timing System

  de Goede, P., Foppen, E., Ritsema, W. I. G. R., Korpel, N. L., Yi, C-X. & Kalsbeek, A., 2019, In: Frontiers in Endocrinology. 10, p. 554

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  • Circadian Clocks
  • Fasting
  • Glucose
  • Insulin Resistance
  • Type 2 Diabetes Mellitus
• 2018

  Administration of thyrotropin-releasing hormone (TRH) in the hypothalamic paraventricular nucleus (PVN) of male rats mimics the metabolic cold defence response

  Zhang, Z., Mansur Machado, F. S., Zhao, L., Heinen, C. A., Foppen, E., Ackermans, M. T., Zhou, J. N., Bisschop, P. H., Boelen, A., Fliers, E. & Kalsbeek, A., 2018, In: Neuroendocrinology. 107, p. 267-279

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File

  • Thyrotropin-Releasing Hormone
  • Paraventricular Hypothalamic Nucleus
  • Cold Temperature
  • Corticosterone
  • Body Temperature
  155 Downloads (Pure)

• A Free-Choice High-Fat High-Sugar Diet Alters Day-Night Gene Expression in Reward-Related Brain Areas in Rats

  Blancas-Velazquez, A. S., Unmehopa, U. A., Eggels, L., Koekkoek, L. L., Kalsbeek, A., Mendoza, J. & la Fleur, S. E., 2018, In: Frontiers in Endocrinology. 9, 154.

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File

  • High Fat Diet
  • Reward
  • Sugars
  • Gene Expression
  • Brain
  122 Downloads (Pure)

• An Ultradian Feeding Schedule in Rats Affects Metabolic Gene Expression in Liver, Brown Adipose Tissue and Skeletal Muscle with Only Mild Effects on Circadian Clocks

  de Goede, P., Sen, S., Su, Y., Foppen, E., Poirel, V-J., Challet, E. & Kalsbeek, A., Sep 2018, In: International Journal of Molecular Sciences. 19, 10, E3171.

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File

  • adipose tissues
  • gene expression
  • skeletal muscle
  • Circadian Clocks
  • Brown Adipose Tissue
  161 Downloads (Pure)

• Chronic infusion of taurolithocholate into the brain increases fat oxidation in mice

  Eggink, H. M., Tambyrajah, L. L., van den Berg, R., Mol, I., van den Heuvel, J. K., Koehorst, M., Groen, A. K., Boelen, A., Kalsbeek, A., Romijn, J. A., Rensen, P. C. N., Kooijman, S. & Soeters, M. R., 2018, In: The Journal of endocrinology. 236, p. 85-97

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File

  • Taurolithocholic Acid
  • GW 4064
  • Fats
  • Bile Acids and Salts
  • Brain
  142 Downloads (Pure)

• Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscle

  Wefers, J., van Moorsel, D., Hansen, J., Connell, N. J., Havekes, B., Hoeks, J., van Marken Lichtenbelt, W. D., Duez, H., Phielix, E., Kalsbeek, A., Boekschoten, M. V., Hooiveld, G. J., Hesselink, M. K. C., Kersten, S., Staels, B., Scheer, F. A. J. L. & Schrauwen, P., 15 Jun 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, p. 7789-7794

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File

  • Fatty Acids
  • Circadian Clocks
  • Insulin Resistance
  • Skeletal Muscle
  • Muscles
  196 Downloads (Pure)

• Circadian rhythms in mitochondrial respiration

  de Goede, P., Wefers, J., Brombacher, E. C., Schrauwen, P. & Kalsbeek, A., 2018, In: Journal of Molecular Endocrinology. 60, p. R115-R130

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File

  • Circadian Rhythm
  • Circadian Clocks
  • Respiration
  • Mitochondria
  • Periodicity
  188 Downloads (Pure)

• Daily Gene Expression Rhythms in Rat White Adipose Tissue Do Not Differ Between Subcutaneous and Intra-Abdominal Depots

  van der Spek, R., Fliers, E., la Fleur, S. E. & Kalsbeek, A., 2018, In: Frontiers in Endocrinology. 9, 206.

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File

  • White Adipose Tissue
  • Periodicity
  • Peroxisome Proliferator-Activated Receptors
  • Gene Expression
  • Fats
  149 Downloads (Pure)

• Deficiency of leptin receptor in myeloid cells disrupts hypothalamic metabolic circuits and causes body weight increase.

  Gao, Y., Vidal-Itriago, A., Milanova, I., Korpel, N. L., Kalsbeek, M. J., Tom, R. Z., Kalsbeek, A., Hofmann, S. M. & Yi, C-X., 2018, In: Molecular Metabolism. 7, p. 155-160

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File
  214 Downloads (Pure)

• Differential effects of diet composition and timing of feeding behavior on rat brown adipose tissue and skeletal muscle peripheral clocks.

  De Goede, P., Sen, S., Oosterman, J. E. & Kalsbeek, A., 2018, In: Neurobiology of Sleep and Circadian Rhythms. 4, p. 24-33

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File

  • Brown Adipose Tissue
  • Feeding Behavior
  • Sugars
  • Skeletal Muscle
  • Diet
  157 Downloads (Pure)

• Effects of Intravenous Thyrotropin Releasing Hormone on 18F-Fluorodeoxyglucose Uptake in Human Brown Adipose Tissue: A Randomized Controlled Trial

  Heinen, C. A., Zhang, Z., Klieverik, L. P., de Wit, T. C., Poel, E., Yaqub, M., Boelen, A., Kalsbeek, A., Bisschop, P. H., van Trotsenburg, P., Verberne, H., Booij, J. & Fliers, E., 2018, In: European Journal of Endocrinology. 179, p. 31-38

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File

  • Thyrotropin-Releasing Hormone
  • Brown Adipose Tissue
  • Fluorodeoxyglucose F18
  • Randomized Controlled Trials
  • Cold Temperature
  139 Downloads (Pure)

• Expression of the clock gene Rev-erbα in the brain controls the circadian organization of food intake and locomotor activity, but not daily variations of energy metabolism

  Sen, S., Dumont, S., Sage-Ciocca, D., Reibel, S., de Goede, P., Kalsbeek, A. & Challet, E., 2018, In: Journal of Neuroendocrinology. 30, e12557.

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File

  • rev Genes
  • Locomotion
  • Energy Metabolism
  • Eating
  • Gene Expression
  163 Downloads (Pure)

• Functional changes of the SCN in spontaneous hypertension but not after the induction of hypertension

  Yilmaz, A., Kalsbeek, A. & Buijs, R. M., 2018, In: Chronobiology International. 35, p. 1221-1235

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File

  • Suprachiasmatic Nucleus
  • Inbred SHR Rats
  • Hypertension
  • Running
  • Darkness
  151 Downloads (Pure)

• The role of the daily feeding rhythm in the regulation of the day/night rhythm in triglyceride secretion in rats

  Su, Y., Foppen, E., Mansur Machado, F. S., Fliers, E. & Kalsbeek, A., 2018, In: Chronobiology International. 35, p. 885-895

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File

  • Triglycerides
  • Feeding Behavior
  • microsomal triglyceride transfer protein
  • Periodicity
  • Apolipoproteins B
  136 Downloads (Pure)

• Time-of-day effects on metabolic and clock-related adjustments to cold.

  Mansur Machado, F. S., Zhang, Z., Su, Y., De Goede, P., Jansen, R., Foppen, E., Coimbra, C. C. & Kalsbeek, A., 2018, In: Frontiers in Endocrinology. 9, 199.

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File

  • Social Adjustment
  • Cold Temperature
  • Brown Adipose Tissue
  • Skeletal Muscle
  • Locomotion
  125 Downloads (Pure)

• Transhepatic bile acid kinetics in pigs and humans

  Eggink, H. M., van Nierop, F. S., Schooneman, M. G., Boelen, A., Kalsbeek, A., Koehorst, M., Ten Have, G. A. M., de Brauw, L. M., Groen, A. K., Romijn, J. A., Deutz, N. E. P. & Soeters, M. R., 2018, In: Clinical Nutrition. 37, p. 1406-1414

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

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  • Bile Acids and Salts
  • Swine
  • Kinetics
  • Meals
  • p-Aminohippuric Acid
  264 Downloads (Pure)

• TRH neurons and thyroid hormone coordinate the hypothalamic response to cold.

  Zhang, Z., Boelen, A., Kalsbeek, A. & Fliers, E., 2018, In: European Thyroid Journal. 7, p. 279-288

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

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  • Thyrotropin-Releasing Hormone
  • Thyroid Hormones
  • Cold Temperature
  • Neurons
  • Brown Adipose Tissue
  113 Downloads (Pure)
• 2017

  Acute Effects of Morning Light on Plasma Glucose and Triglycerides in Healthy Men and Men with Type 2 Diabetes

  Versteeg, R. I., Stenvers, D. J., Visintainer, D., Linnenbank, A., Tanck, M. W., Zwanenburg, G., Smilde, A. K., Fliers, E., Kalsbeek, A., Serlie, M. J., la Fleur, S. E. & Bisschop, P. H., Apr 2017, In: Journal of Biological Rhythms. 32, 2, p. 130-142

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File

  • Triglycerides
  • Type 2 Diabetes Mellitus
  • Light
  • Glucose
  • Fasting
  177 Downloads (Pure)

• Bile acid signaling pathways from the enterohepatic circulation to the central nervous system.

  Mertens, K. L., Kalsbeek, A., Soeters, M. R. & Eggink, H. M., 2017, In: Frontiers in Neuroscience. 11, 617.

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File
  171 Downloads (Pure)

• Circadian and endocrine rhythms

  Kalsbeek, A. & Fliers, E., 2017, In: Best Practice and Research in Clinical Endocrinology and Metabolism. 31, 5, p. 443

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

• Complex interaction between circadian rhythm and diet on bile acid homeostasis in male rats

  Eggink, H. M., Oosterman, J. E., de Goede, P., de Vries, E. M., Foppen, E., Koehorst, M., Groen, A. K., Boelen, A., Romijn, J. A., la Fleur, S. E., Soeters, M. R. & Kalsbeek, A., 2017, In: Chronobiology International. 34, p. 1339-1353

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File

  • Circadian Rhythm
  • Bile Acids and Salts
  • Homeostasis
  • Diet
  • High Fat Diet
  93 Downloads (Pure)

• Dietary sugars, not lipids, drive hypothalamic inflammation

  Gao, Y., Bielohuby, M., Fleming, T., Grabner, G. F., Foppen, E., Bernhard, W., Guzmán-Ruiz, M., Layritz, C., Legutko, B., Zinser, E., García-Cáceres, C., Buijs, R. M., Woods, S. C., Kalsbeek, A., Seeley, R. J., Nawroth, P. P., Bidlingmaier, M., Tschöp, M. H. & Yi, C-X., Jul 2017, In: Molecular Metabolism. 6, 8, p. 897-908 12 p.

  Research output: Contribution to journal/periodical › Article › Scientific › peer-review

  Open Access

  File

  • Dietary Sugars
  • High Fat Diet
  • Carbohydrates
  • Activated-Leukocyte Cell Adhesion Molecule
  • Lipids
  481 Downloads (Pure)