Air Ambulance: Antimicrobial Power of Bacterial Volatiles

A. Lammers (Corresponding author), Michael Lalk, Paolina Garbeva

Research output: Contribution to journal/periodicalArticleScientificpeer-review

17 Citations (Scopus)
123 Downloads (Pure)

Abstract

We are currently facing an antimicrobial resistance crisis, which means that a lot of bacterial pathogens have developed resistance to common antibiotics. Hence, novel and innovative solutions are urgently needed to combat resistant human pathogens. A new source of antimicrobial compounds could be bacterial volatiles. Volatiles are ubiquitous produced, chemically divers and playing essential roles in intra- and interspecies interactions like communication and antimicrobial defense. In the last years, an increasing number of studies showed bioactivities of bacterial volatiles, including antibacterial, antifungal and anti-oomycete activities, indicating bacterial volatiles as an exciting source for novel antimicrobial compounds. In this review we introduce the chemical diversity of bacterial volatiles, their antimicrobial activities and methods for testing this activity. Concluding, we discuss the possibility of using antimicrobial volatiles to antagonize the antimicrobial resistance crisis.
Original languageEnglish
Article number109
Number of pages15
JournalAntibiotics
Volume11
Issue number1
Early online date2022
DOIs
Publication statusPublished - 2022

Keywords

  • international
  • Plan_S-Compliant-OA

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