APCmin tumors need a SPARC

A. Gregorrieff, J.C. Clevers

Research output: Contribution to journal/periodicalArticleScientificpeer-review


The interaction between cancer cells and their microenviroment strongly influences growth and invasiveness of neoplasia. In this issue of Gut, a new study identifies the extracellular matrix (ECM) component, SPARC, as a critical determinant of tumor burden in the APCmin/+ model of intestinal cancer.
Original languageEnglish
Publication statusPublished - 2007


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