APCmin tumors need a SPARC

A. Gregorrieff; J.C. Clevers

APCmin tumors need a SPARC

A. Gregorrieff
, J.C. Clevers

Hubrecht Institute

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

Abstract

The interaction between cancer cells and their microenviroment strongly influences growth and invasiveness of neoplasia. In this issue of Gut, a new study identifies the extracellular matrix (ECM) component, SPARC, as a critical determinant of tumor burden in the APCmin/+ model of intestinal cancer.

Original language	English
Journal	Gut
Volume	56
Publication status	Published - 2007

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title = "APCmin tumors need a SPARC",

abstract = "The interaction between cancer cells and their microenviroment strongly influences growth and invasiveness of neoplasia. In this issue of Gut, a new study identifies the extracellular matrix (ECM) component, SPARC, as a critical determinant of tumor burden in the APCmin/+ model of intestinal cancer.",

author = "A. Gregorrieff and J.C. Clevers",

note = "doi:10.1136/gut.2007.122135; Publication ehaed of print.",

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AU - Gregorrieff, A.

AU - Clevers, J.C.

N1 - doi:10.1136/gut.2007.122135; Publication ehaed of print.

PY - 2007

Y1 - 2007

N2 - The interaction between cancer cells and their microenviroment strongly influences growth and invasiveness of neoplasia. In this issue of Gut, a new study identifies the extracellular matrix (ECM) component, SPARC, as a critical determinant of tumor burden in the APCmin/+ model of intestinal cancer.

AB - The interaction between cancer cells and their microenviroment strongly influences growth and invasiveness of neoplasia. In this issue of Gut, a new study identifies the extracellular matrix (ECM) component, SPARC, as a critical determinant of tumor burden in the APCmin/+ model of intestinal cancer.

M3 - Article

SN - 0017-5749

VL - 56

JO - Gut

JF - Gut

ER -

APCmin tumors need a SPARC

Abstract

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