Biosynthesis, Evolution and Ecology of Microbial Terpenoids

Mariana Avalos Garcia (Corresponding author), Paolina Garbeva, Lisa Vader, Gilles van Wezel, J.S. Dickschat, Dana Ulanova

Research output: Contribution to journal/periodicalBook/Film/Article reviewScientific

46 Citations (Scopus)
117 Downloads (Pure)

Abstract

Terpenoids are the largest class of natural products recognised to date. While mostly known to humans as bioactive plant metabolites and part of essential oils, structurally diverse terpenoids are increasingly reported to be produced by microorganisms. For many of the compounds biological functions are yet unknown, but during the past years significant insights have been obtained for the role of terpenoids in microbial chemical ecology. Their functions include stress alleviation, maintenance of cell membrane integrity, photoprotection, attraction or repulsion of organisms, host growth promotion and defense. In this review we discuss the current knowledge of the biosynthesis and evolution of microbial terpenoids, and their ecological and biological roles in aquatic and terrestrial environments. Perspectives on their biotechnological applications, knowledge gaps and questions for future studies are discussed.
Original languageEnglish
Pages (from-to)249-272
Number of pages24
JournalNatural Product Reports
Volume39
Issue number2
Early online date2021
DOIs
Publication statusPublished - 2022

Keywords

  • international
  • Plan_S-Compliant_NO

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