Bipolaris oryzae, a novel fungal opportunist causing keratitis

    Research output: Working paper/discussion paperWeb articleScientificpeer-review


    We report a case of mycotic keratitis caused by Bipolaris oryzae with predisposing trauma from a foreign body. The fungus was identified by sequencing the internal transcribed spacer (ITS) region, translation elongation factor 1α (TEF1) gene and partial glyceraldehyde-3-phosphate dehydrogenase (GPDH) gene, and the species identity was confirmed on the basis of its characteristic conidial phenotype. The patient was treated with surgical intervention and antifungal agents, including intravenous fluconazole (FLC), oral itraconazole (ITZ), topical 0.15% amphotericin B (AmB) eye drops, and 0.5% FLC eye drops. To our knowledge, this is the first report of mycotic keratitis caused by B. oryzae worldwide.
    Original languageEnglish
    Number of pages5
    Publication statusPublished - 2015

    Publication series

    ISSN (Electronic)0732-8893


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