Birth and upgrowth of the Hox topological domains during evolution

Jacqueline Deschamps

Research output: Contribution to journal/periodicalArticleScientificpeer-review


The recently discovered chromatin compartments called topologically associating domains (TADs) are essential for the three-dimensional organization of regulatory interactions driving gene expression. A new study documents the emergence of a TAD flanking the amphioxus Hox cluster, prefiguring the vertebrate anterior Hox TAD and preceding the appearance of the concurring posterior Hox TAD.

Original languageEnglish
Pages (from-to)227-8
Number of pages2
JournalNature Genetics
Issue number3
Publication statusPublished - Mar 2016


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