Can We Just Say: Transcription Second?

Peter Hugo Lodewijk Krijger; Wouter de Laat

doi:10.1016/j.cell.2017.03.026

Can We Just Say: Transcription Second?

Peter Hugo Lodewijk Krijger, Wouter de Laat

Hubrecht Institute

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

6 Citations (Scopus)

Abstract

The striking correlation between genome topology and transcriptional activity has for decades made researchers revisit the question, "Does form follow function, or does function follow form?" In a new study, Hug et al. address this question by comparing the timing of zygotic genome activation to the emergence of genome structures during Drosophila embryogenesis.

Original language	English
Pages (from-to)	184-185
Number of pages	2
Journal	Cell
Volume	169
Issue number	2
DOIs	https://doi.org/10.1016/j.cell.2017.03.026
Publication status	Published - 06 Apr 2017

Keywords

Animals
Drosophila melanogaster
Embryonic Development
Gene Expression Regulation, Developmental
Genome
Zygote
Journal Article

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10.1016/j.cell.2017.03.026

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title = "Can We Just Say: Transcription Second?",

abstract = "The striking correlation between genome topology and transcriptional activity has for decades made researchers revisit the question, {"}Does form follow function, or does function follow form?{"} In a new study, Hug et al. address this question by comparing the timing of zygotic genome activation to the emergence of genome structures during Drosophila embryogenesis.",

keywords = "Animals, Drosophila melanogaster, Embryonic Development, Gene Expression Regulation, Developmental, Genome, Zygote, Journal Article",

author = "Krijger, {Peter Hugo Lodewijk} and {de Laat}, Wouter",

year = "2017",

month = apr,

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doi = "10.1016/j.cell.2017.03.026",

language = "English",

volume = "169",

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journal = "Cell",

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AU - Krijger, Peter Hugo Lodewijk

AU - de Laat, Wouter

PY - 2017/4/6

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AB - The striking correlation between genome topology and transcriptional activity has for decades made researchers revisit the question, "Does form follow function, or does function follow form?" In a new study, Hug et al. address this question by comparing the timing of zygotic genome activation to the emergence of genome structures during Drosophila embryogenesis.

KW - Animals

KW - Drosophila melanogaster

KW - Embryonic Development

KW - Gene Expression Regulation, Developmental

KW - Genome

KW - Zygote

KW - Journal Article

U2 - 10.1016/j.cell.2017.03.026

DO - 10.1016/j.cell.2017.03.026

M3 - Article

C2 - 28388402

SN - 0092-8674

VL - 169

SP - 184

EP - 185

JO - Cell

JF - Cell

IS - 2

ER -

Can We Just Say: Transcription Second?

Abstract

Keywords

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