Cerebellar imaging at ultra-high magnetic fields.

W. Van der Zwaag; D. Timmann; A. Deistung; Nikos Priovoulos

Cerebellar imaging at ultra-high magnetic fields.

W. Van der Zwaag, D. Timmann, A. Deistung, Nikos Priovoulos

Netherlands Institute for Neuroscience (NIN)

Research output: Chapter in book/volume › Chapter › Scientific › peer-review

Abstract

The cerebellum is a finely structured brain area positioned below the occipital lobe. It is involved in tasks ranging from motor tuning to emotional control. The cerebellum can be affected by diseases such as spinocerebellar ataxias or multiple sclerosis, which can both lead to a wide range of symptoms. As the cerebellar cortex is about 1 mm thick or less, cerebellar imaging profits from ultra-high field (UHF) because of the available high spatial resolution. Extra care should be taken to avoid signal loss due to B0 and B1 inhomogeneities. Data processing and analysis can also be a challenge, as only a few tools are dedicated to cerebellum analysis. T1-weighted imaging offers exquisite details of the cerebellar cortex. The iron-rich deep nuclei, especially the dentate nucleus, can be visualized in detail with QSM or other iron-sensitive imaging techniques. Structural imaging at UHF is expected to offer new insights into cerebellar pathologies.

Original language	English
Title of host publication	Advances in Magnetic Resonance Technology and Applications. Ultra-High Field Neuro MRI
Publisher	Elsevier/North-Holland Biomedical Press
Chapter	15
Pages	245-258
Publication status	Published - 2023

Cite this

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title = "Cerebellar imaging at ultra-high magnetic fields.",

abstract = "The cerebellum is a finely structured brain area positioned below the occipital lobe. It is involved in tasks ranging from motor tuning to emotional control. The cerebellum can be affected by diseases such as spinocerebellar ataxias or multiple sclerosis, which can both lead to a wide range of symptoms. As the cerebellar cortex is about 1 mm thick or less, cerebellar imaging profits from ultra-high field (UHF) because of the available high spatial resolution. Extra care should be taken to avoid signal loss due to B0 and B1 inhomogeneities. Data processing and analysis can also be a challenge, as only a few tools are dedicated to cerebellum analysis. T1-weighted imaging offers exquisite details of the cerebellar cortex. The iron-rich deep nuclei, especially the dentate nucleus, can be visualized in detail with QSM or other iron-sensitive imaging techniques. Structural imaging at UHF is expected to offer new insights into cerebellar pathologies.",

author = "{Van der Zwaag}, W. and D. Timmann and A. Deistung and Nikos Priovoulos",

year = "2023",

language = "English",

pages = "245--258",

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TY - CHAP

T1 - Cerebellar imaging at ultra-high magnetic fields.

AU - Van der Zwaag, W.

AU - Timmann, D.

AU - Deistung, A.

AU - Priovoulos, Nikos

PY - 2023

Y1 - 2023

N2 - The cerebellum is a finely structured brain area positioned below the occipital lobe. It is involved in tasks ranging from motor tuning to emotional control. The cerebellum can be affected by diseases such as spinocerebellar ataxias or multiple sclerosis, which can both lead to a wide range of symptoms. As the cerebellar cortex is about 1 mm thick or less, cerebellar imaging profits from ultra-high field (UHF) because of the available high spatial resolution. Extra care should be taken to avoid signal loss due to B0 and B1 inhomogeneities. Data processing and analysis can also be a challenge, as only a few tools are dedicated to cerebellum analysis. T1-weighted imaging offers exquisite details of the cerebellar cortex. The iron-rich deep nuclei, especially the dentate nucleus, can be visualized in detail with QSM or other iron-sensitive imaging techniques. Structural imaging at UHF is expected to offer new insights into cerebellar pathologies.

AB - The cerebellum is a finely structured brain area positioned below the occipital lobe. It is involved in tasks ranging from motor tuning to emotional control. The cerebellum can be affected by diseases such as spinocerebellar ataxias or multiple sclerosis, which can both lead to a wide range of symptoms. As the cerebellar cortex is about 1 mm thick or less, cerebellar imaging profits from ultra-high field (UHF) because of the available high spatial resolution. Extra care should be taken to avoid signal loss due to B0 and B1 inhomogeneities. Data processing and analysis can also be a challenge, as only a few tools are dedicated to cerebellum analysis. T1-weighted imaging offers exquisite details of the cerebellar cortex. The iron-rich deep nuclei, especially the dentate nucleus, can be visualized in detail with QSM or other iron-sensitive imaging techniques. Structural imaging at UHF is expected to offer new insights into cerebellar pathologies.

M3 - Chapter

SP - 245

EP - 258

BT - Advances in Magnetic Resonance Technology and Applications. Ultra-High Field Neuro MRI

PB - Elsevier/North-Holland Biomedical Press

ER -

Cerebellar imaging at ultra-high magnetic fields.

Abstract

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