Comparative analysis of basidiomycete transcriptomes reveals a core set of expressed genes encoding plant biomass degrading enzymes

Mao Peng, Maria Victoria Aguilar-Pontes, Matthieu Hainaut, Bernard Henrissat, Kristiina Hildén, Miia R Mäkelä, Ronald P de Vries

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Abstract

Basidiomycete fungi can degrade a wide range of plant biomass, including living and dead trees, forest litter, crops, and plant matter in soils. Understanding the process of plant biomass decay by basidiomycetes could facilitate their application in various industrial sectors such as food & feed, detergents and biofuels, and also provide new insights into their essential biological role in the global carbon cycle. The fast expansion of basidiomycete genomic and functional genomics data (e.g. transcriptomics, proteomics) has facilitated exploration of key genes and regulatory mechanisms of plant biomass degradation. In this study, we comparatively analyzed 22 transcriptome datasets from basidiomycetes related to plant biomass degradation, and identified 328 commonly induced genes and 318 repressed genes, and defined a core set of carbohydrate active enzymes (CAZymes), which was shared by most of the basidiomycete species. High conservation of these CAZymes in genomes and similar regulation pattern in transcriptomics data from lignocellulosic substrates indicate their key role in plant biomass degradation and need for their further biochemical investigation.

Original languageEnglish
Pages (from-to)40-46
JournalFungal Genetics and Biology
Early online date10 Aug 2017
DOIs
Publication statusPublished - Mar 2018

Keywords

  • Basidiomycete
  • Plant biomass degradation
  • Comparative transcriptomics
  • CAZymes

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