This document contains the full text of the CoreTrustSeal Trustworthy Data Repositories Requirements for 2020–2022 (https://doi.org/10.5281/zenodo.3638211) with introductory paragraphs on Background & General Guidance. In addition to the CoreTrustSeal Requirements, which remain stable for the period 2020–2022, this document provides the Extended Guidance for CoreTrustSeal reviewers and applicants. The Extended Guidance text may be updated during the period 2020–2022 subject to approval by the CoreTrustSeal Board. The document also contains a reference to the Glossary of Terms. The document is intended to maximize consistency of reviews across the wide range of CoreTrustSeal applicants. The primary audience is reviewers, but it is also useful for applicants when preparing an application self-assessment.