Dcr1 tracked down

L.J. Kaaij; R.F. Ketting

doi:10.1016/j.devcel.2010.01.001

Dcr1 tracked down

L.J. Kaaij
, R.F. Ketting

Hubrecht Institute

Unknown

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

Abstract

RNAi is essential for pericentromeric heterochromatic formation in S. pombe, and although Dcr1, the initiator protein of this process, has been biochemically well described, its subcellular localization has remained elusive. In this issue of Developmental Cell, Emmerth et al. now show that Dcr1 is dynamically shuttling between nucleus and cytoplasm, adding new insight into the subcellular mechanics of RNAi.

Original language	English
Pages (from-to)	6-7
Journal	Developmental Cell
Volume	18
Issue number	1
DOIs	https://doi.org/10.1016/j.devcel.2010.01.001
Publication status	Published - 2010

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10.1016/j.devcel.2010.01.001

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title = "Dcr1 tracked down",

abstract = "RNAi is essential for pericentromeric heterochromatic formation in S. pombe, and although Dcr1, the initiator protein of this process, has been biochemically well described, its subcellular localization has remained elusive. In this issue of Developmental Cell, Emmerth et al. now show that Dcr1 is dynamically shuttling between nucleus and cytoplasm, adding new insight into the subcellular mechanics of RNAi.",

author = "L.J. Kaaij and R.F. Ketting",

note = "Reporting year: 2010 Metis note: S1534-5807(10)00002-X [pii]",

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AU - Ketting, R.F.

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PY - 2010

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AB - RNAi is essential for pericentromeric heterochromatic formation in S. pombe, and although Dcr1, the initiator protein of this process, has been biochemically well described, its subcellular localization has remained elusive. In this issue of Developmental Cell, Emmerth et al. now show that Dcr1 is dynamically shuttling between nucleus and cytoplasm, adding new insight into the subcellular mechanics of RNAi.

U2 - 10.1016/j.devcel.2010.01.001

DO - 10.1016/j.devcel.2010.01.001

M3 - Article

SN - 1534-5807

VL - 18

SP - 6

EP - 7

JO - Developmental Cell

JF - Developmental Cell

IS - 1

ER -

Dcr1 tracked down

Abstract

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