Effect of donor-recipient relatedness on the plasmid conjugation frequency: a meta-analysis

Jesse B. Alderliesten; Sarah J. N. Duxbury; Mark P. Zwart; J. Arjan G. M. de Visser; Arjan Stegeman; Egil A. J. Fischer

doi:10.1186/s12866-020-01825-4

Effect of donor-recipient relatedness on the plasmid conjugation frequency: a meta-analysis

Jesse B. Alderliesten (Corresponding author), Sarah J. N. Duxbury, Mark P. Zwart, J. Arjan G. M. de Visser, Arjan Stegeman, Egil A. J. Fischer

NIOO - Microbial Ecology (ME)

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Abstract

Conjugation plays a major role in the transmission of plasmids encoding antibiotic resistance genes in both clinical and general settings. The conjugation efficiency is influenced by many biotic and abiotic factors, one of which is the taxonomic relatedness between donor and recipient bacteria. A comprehensive overview of the influence of donor-recipient relatedness on conjugation is still lacking, but such an overview is important to quantitatively assess the risk of plasmid transfer and the effect of interventions which limit the spread of antibiotic resistance, and to obtain parameter values for conjugation in mathematical models. Therefore, we performed a meta-analysis on reported conjugation frequencies from Escherichia coli donors to various recipient species.

Original language	English
Journal	BMC Microbiology
Volume	20
Issue number	1
DOIs	https://doi.org/10.1186/s12866-020-01825-4
Publication status	Published - 2020

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national
Plan_S-Compliant-OA

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10.1186/s12866-020-01825-4Licence: CC BY

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abstract = "Conjugation plays a major role in the transmission of plasmids encoding antibiotic resistance genes in both clinical and general settings. The conjugation efficiency is influenced by many biotic and abiotic factors, one of which is the taxonomic relatedness between donor and recipient bacteria. A comprehensive overview of the influence of donor-recipient relatedness on conjugation is still lacking, but such an overview is important to quantitatively assess the risk of plasmid transfer and the effect of interventions which limit the spread of antibiotic resistance, and to obtain parameter values for conjugation in mathematical models. Therefore, we performed a meta-analysis on reported conjugation frequencies from Escherichia coli donors to various recipient species.",

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AU - Alderliesten, Jesse B.

AU - Duxbury, Sarah J. N.

AU - Zwart, Mark P.

AU - de Visser, J. Arjan G. M.

AU - Stegeman, Arjan

AU - Fischer, Egil A. J.

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JF - BMC Microbiology

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Effect of donor-recipient relatedness on the plasmid conjugation frequency: a meta-analysis

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