Fatal Cryptococcus gattii genotype AFLP5 infection in an immunocompetent Cuban patient

María T Illnait-Zaragozí; Lilia M Ortega-Gonzalez; Ferry Hagen; Gerardo F Martínez-Machin; Jacques F Meis

doi:10.1016/j.mmcr.2013.02.001

Fatal Cryptococcus gattii genotype AFLP5 infection in an immunocompetent Cuban patient

María T Illnait-Zaragozí, Lilia M Ortega-Gonzalez, Ferry Hagen, Gerardo F Martínez-Machin, Jacques F Meis

Westerdijk Fungal Biodiversity Institute

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

17 Citations (Scopus)

Abstract

We describe the first clinical case of cryptococcosis due C. gattii in a Cuban immunocompetent patient who had a traveling history two years before to Central America. Molecular characterization of the isolate showed it to be genotype AFLP5 of which MLST sequences clustered with clinical and environmental strains from Colombia. The patient died one year after the diagnosis despite a prolonged treatment with (liposomal) amphotericin B, fluconazole, voriconazole and gamma interferon.

Original language	English
Pages (from-to)	48-51
Number of pages	4
Journal	Medical Mycology Case Reports
Volume	2
DOIs	https://doi.org/10.1016/j.mmcr.2013.02.001
Publication status	Published - 09 Feb 2013

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abstract = "We describe the first clinical case of cryptococcosis due C. gattii in a Cuban immunocompetent patient who had a traveling history two years before to Central America. Molecular characterization of the isolate showed it to be genotype AFLP5 of which MLST sequences clustered with clinical and environmental strains from Colombia. The patient died one year after the diagnosis despite a prolonged treatment with (liposomal) amphotericin B, fluconazole, voriconazole and gamma interferon. ",

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AU - Illnait-Zaragozí, María T

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AU - Hagen, Ferry

AU - Martínez-Machin, Gerardo F

AU - Meis, Jacques F

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AB - We describe the first clinical case of cryptococcosis due C. gattii in a Cuban immunocompetent patient who had a traveling history two years before to Central America. Molecular characterization of the isolate showed it to be genotype AFLP5 of which MLST sequences clustered with clinical and environmental strains from Colombia. The patient died one year after the diagnosis despite a prolonged treatment with (liposomal) amphotericin B, fluconazole, voriconazole and gamma interferon.

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JO - Medical Mycology Case Reports

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Fatal Cryptococcus gattii genotype AFLP5 infection in an immunocompetent Cuban patient

Abstract

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