Five Challenges in the Field of Viral Diversity and Evolution

Rafael Sanjuán; Christopher J.R. Illingworth; Jemma L. Geoghegan; Jaime Iranzo; Mark Zwart; Alexander T. Ciota; Gonzalo Moratorio; Selma Gago-Zachert; Siobain Duffy; Dhanasekaran Vijaykrishna

doi:10.3389/fviro.2021.684949

Five Challenges in the Field of Viral Diversity and Evolution

Rafael Sanjuán (Corresponding author)
, Christopher J.R. Illingworth
, Jemma L. Geoghegan
, Jaime Iranzo
, Mark Zwart
, Alexander T. Ciota
, Gonzalo Moratorio
, Selma Gago-Zachert
, Siobain Duffy
, Dhanasekaran Vijaykrishna

NIOO - Microbial Ecology (ME)

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

10 Citations (Scopus)

99 Downloads (Pure)

Abstract

Viral diversity and evolution play a central role in processes such as disease emergence, vaccine failure, drug resistance, and virulence. However, significant challenges remain to better understand and manage these processes. Here, we discuss five of these challenges. These include improving our ability to predict viral evolution, developing more relevant experimental evolutionary systems, integrating viral dynamics and evolution at different scales, systematic appraisal of the virosphere, and deepening our understanding of virus-virus interactions. Intensifying future research on these areas should improve our ability to combat viral diseases, as well as to exploit viral diversity and evolution for biotechnological purposes.

Original language	English
Article number	684949
Pages (from-to)	1-5
Number of pages	5
Journal	Frontiers in Virology
Volume	1
DOIs	https://doi.org/10.3389/fviro.2021.684949
Publication status	Published - 29 Apr 2021

Keywords

international
Plan_S-Compliant_OA

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AU - Sanjuán, Rafael

AU - Illingworth, Christopher J.R.

AU - Geoghegan, Jemma L.

AU - Iranzo, Jaime

AU - Zwart, Mark

AU - Ciota, Alexander T.

AU - Moratorio, Gonzalo

AU - Gago-Zachert, Selma

AU - Duffy, Siobain

AU - Vijaykrishna, Dhanasekaran

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JO - Frontiers in Virology

JF - Frontiers in Virology

M1 - 684949

ER -

Five Challenges in the Field of Viral Diversity and Evolution

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