Fusarium volatile, a new potential pathogen from a human respiratory sample

A.M.S. Al-Hatmi, M. Sandoval-Denis, C. Nabet, S.A. Ahmed, M. Demar, A.-C. Normand, G.S. de Hoog

Research output: Contribution to conferenceAbstractScientific

Abstract

We describe the isolation and characterization of Fusarium volatile from a bronchoalveolar lavage (BAL) sample of a female patient living in French Guiana with underlying pulmonary infections. Phylogenetic analysis of fragments of the calmodulin (cmdA), translation elongation factor (tef1), RNA polymerase second largest subunit (rpb2), and β-tubulin (tub) loci revealed that strain CBS 143874 was closely related to isolate NRRL 25615, a known but undescribed phylogenetic species belonging to the African clade of the Fusarium fujikuroi species complex. The fungus differed phylogenetically and morphologically from related known species, and is therefore described as the new taxon Fusarium volatile. Antifungal susceptibility testing suggested that the new species is resistant to echinocandins, fluconazole, itraconazole with lower MICs against amphotericin B, voriconazole and posaconazole.
Original languageEnglish
Pages171-181
Number of pages11
DOIs
Publication statusPublished - Dec 2019

Keywords

  • CLINICAL SAMPLES
  • FFSC
  • PHYLOGENY
  • FUNGAL TAXONOMY
  • FRENCH GUIANA

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    Al-Hatmi, A. M. S., Sandoval-Denis, M., Nabet, C., Ahmed, S. A., Demar, M., Normand, A-C., & de Hoog, G. S. (2019). Fusarium volatile, a new potential pathogen from a human respiratory sample. 171-181. https://doi.org/10.3114/fuse.2019.04.09