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Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors

  • Zachary Steinhart
  • , Zvezdan Pavlovic
  • , Megha Chandrashekhar
  • , Traver Hart
  • , Xiaowei Wang
  • , Xiaoyu Zhang
  • , Mélanie Robitaille
  • , Kevin R Brown
  • , Sridevi Jaksani
  • , René Overmeer
  • , Sylvia F Boj
  • , Jarrett Adams
  • , James Pan
  • , Hans Clevers
  • , Sachdev Sidhu
  • , Jason Moffat
  • , Stéphane Angers

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

240 Citations (Scopus)

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Biochemistry, Genetics and Molecular Biology