Getting the genome in shape: the formation of loops, domains and compartments

Britta Am Bouwman, Wouter de Laat

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Abstract

The hierarchical levels of genome architecture exert transcriptional control by tuning the accessibility and proximity of genes and regulatory elements. Here, we review current insights into the trans-acting factors that enable the genome to flexibly adopt different functionally relevant conformations.

Original languageEnglish
Pages (from-to)154
JournalGenome Biology
Volume16
DOIs
Publication statusPublished - 2015

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