Identification of a rat model for usher syndrome type 1B by N-ethyl-N-nitrosourea mutagenesis-driven forward genetics

Keyphrases

• ENU mutagenesis 100%
• Syndrome Type 100%
• MYO7A 100%
• Profound Deafness 50%
• Phenotypic Screen 50%
• Head Shaking 50%
• Tornado 50%
• Recessive Disease 50%
• Vestibular Disorders 50%
• Human Disease Models 50%

Biochemistry, Genetics and Molecular Biology

• Mutagenesis 100%
• Forward Genetics 100%
• Rat Model 100%
• Point Mutation 33%
• Genetic Divergence 33%
• Single-Nucleotide Polymorphism 33%
• Genetic Variation 33%
• Candidate Gene 33%
• Gene Linkage 33%
• Experimental Rat 33%
• Chromosome 1 33%
• Spontaneous Mutation 33%
• Circling Behavior 33%

Neuroscience

• Nitrosourea 100%
• Mutagenesis 100%
• Behavior (Neuroscience) 33%
• Single-Nucleotide Polymorphism 33%
• Point Mutation 33%
• Genetic Variation 33%
• Disorientation 33%
• Chromosome 1 33%
• Hyperactivity 33%
• Sensation of Hearing 33%