In Vitro Activities of Eight Antifungal Drugs against 106 Waterborne and Cutaneous Exophiala Species

TY - JOUR

T1 - In Vitro Activities of Eight Antifungal Drugs against 106 Waterborne and Cutaneous Exophiala Species

AU - Najafzadeh, M.J.

AU - Saradeghi Keisari, M.

AU - Vicente, V.A.

AU - Feng, P.

AU - Shamsian, S.A.

AU - Rezaei-Matehkolaei, A.

AU - de Hoog, G.S.

AU - Curfs-Breuker, I.

AU - Meis, J.F.G.M.

N1 - Reporting year: 2013

PY - 2013

Y1 - 2013

N2 - The in vitro activities of eight antifungal drugs against 106 clinical and environmental isolates of waterborne and cutaneous Exophiala species were tested. The MICs and minimum effective concentrations for 90% of the strains tested (n = 106) were, in increasing order, as follows: posaconazole, 0.063 mug/ml; itraconazole, 0.25 mug/ml; micafungin, 1 mug/ml; voriconazole, 2 mug/ml; isavuconazole, 4 mug/ml; caspofungin, 8 mug/ml; amphotericin B, 16 mug/ml; fluconazole, 64 mug/ml.

AB - The in vitro activities of eight antifungal drugs against 106 clinical and environmental isolates of waterborne and cutaneous Exophiala species were tested. The MICs and minimum effective concentrations for 90% of the strains tested (n = 106) were, in increasing order, as follows: posaconazole, 0.063 mug/ml; itraconazole, 0.25 mug/ml; micafungin, 1 mug/ml; voriconazole, 2 mug/ml; isavuconazole, 4 mug/ml; caspofungin, 8 mug/ml; amphotericin B, 16 mug/ml; fluconazole, 64 mug/ml.

U2 - 10.1128/AAC.01629-13

DO - 10.1128/AAC.01629-13

M3 - Article

SN - 0066-4804

VL - 57

SP - 6395

EP - 6398

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

IS - 12

ER -