In Vitro Activities of Eight Antifungal Drugs against a Global Collection of Genotyped Exserohilum Isolates

Anuradha Chowdhary, Ferry Hagen, Ilse Curfs-Breuker, Hugo Madrid, G Sybren de Hoog, Jacques F Meis

    Research output: Contribution to journal/periodicalArticleScientificpeer-review

    Abstract

    The in vitro susceptibilities of 24 worldwide Exserohilum isolates belonging to 10 species from human and environmental sources were determined for eight antifungal drugs. The strains were characterized by internal transcribed spacer (ITS) sequencing and amplified fragment length polymorphism fingerprinting. Posaconazole had the lowest geometric mean MIC (0.16 μg/ml), followed by micafungin (0.21 μg/ml), amphotericin B (0.24 μg/ml), itraconazole (0.33 μg/ml), voriconazole (0.8 μg/ml), caspofungin (1.05 μg/ml), isavuconazole (1.38 μg/ml), and fluconazole (15.6 μg/ml).

    Original languageEnglish
    Pages (from-to)6642-5
    Number of pages4
    JournalAntimicrobial Agents and Chemotherapy
    Volume59
    Issue number10
    DOIs
    Publication statusPublished - Oct 2015

    Fingerprint

    Dive into the research topics of 'In Vitro Activities of Eight Antifungal Drugs against a Global Collection of Genotyped Exserohilum Isolates'. Together they form a unique fingerprint.

    Cite this