In Vitro Activity of Isavuconazole against Rasamsonia Species

J Steinmann; S Dittmer; J Houbraken; J Buer; P-M Rath

doi:10.1128/AAC.00742-16

In Vitro Activity of Isavuconazole against Rasamsonia Species

J Steinmann, S Dittmer, J Houbraken, J Buer, P-M Rath

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

18 Citations (Scopus)

Abstract

The in vitro susceptibilities to the novel triazole isavuconazole and six other antifungal agents of a large collection of Rasamsonia isolates (n = 47) belonging to seven species were determined. Isavuconazole and voriconazole had no in vitro activity (MIC, >32 mg/liter) against isolates of the Rasamsonia argillacea species complex. The echinocandins were the most potent antifungal drugs against all of the isolates tested (minimum effective concentration, ≤0.19 mg/liter).

Original language	English
Pages (from-to)	6890-6891
Number of pages	2
Journal	Antimicrobial Agents and Chemotherapy
Volume	60
Issue number	11
DOIs	https://doi.org/10.1128/AAC.00742-16
Publication status	Published - Nov 2016

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abstract = "The in vitro susceptibilities to the novel triazole isavuconazole and six other antifungal agents of a large collection of Rasamsonia isolates (n = 47) belonging to seven species were determined. Isavuconazole and voriconazole had no in vitro activity (MIC, >32 mg/liter) against isolates of the Rasamsonia argillacea species complex. The echinocandins were the most potent antifungal drugs against all of the isolates tested (minimum effective concentration, ≤0.19 mg/liter).",

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AU - Steinmann, J

AU - Dittmer, S

AU - Houbraken, J

AU - Buer, J

AU - Rath, P-M

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AB - The in vitro susceptibilities to the novel triazole isavuconazole and six other antifungal agents of a large collection of Rasamsonia isolates (n = 47) belonging to seven species were determined. Isavuconazole and voriconazole had no in vitro activity (MIC, >32 mg/liter) against isolates of the Rasamsonia argillacea species complex. The echinocandins were the most potent antifungal drugs against all of the isolates tested (minimum effective concentration, ≤0.19 mg/liter).

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DO - 10.1128/AAC.00742-16

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VL - 60

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EP - 6891

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

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ER -

In Vitro Activity of Isavuconazole against Rasamsonia Species

Abstract

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