Insomnia disorder subtypes derived from life history and traits of affect and personality.

T.F. Blanken, Jeroen S Benjamins, Denny Borsboom, Jeroen K. Vermunt, Casey Paquola, Jennifer R Ramautar, Kim Dekker, D. Stoffers, Rick Wassing, Yishul Wei, E.J.W. van Someren

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Insomnia disorder is the second most prevalent mental disorder, and it is a primary risk factor for depression. Inconsistent clinical and biomarker findings in patients with insomnia disorder suggest that heterogeneity exists and that subtypes of this disease remain unrecognised. Previous top-down proposed subtypes in nosologies
have had insufficient validity. In this large-scale study, we aimed to reveal robust subtypes of insomnia disorder by use of data-driven analyses on a multidimensional set of biologically based traits.
Original languageEnglish
Pages (from-to)151-163
JournalThe Lancet Psychiatry
Publication statusPublished - 08 Jan 2019


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