Intestinal Inflammation and Dysregulated Immunity in Patients With Inherited Caspase-8 Deficiency

Anna S Lehle, Henner F Farin, Benjamin Marquardt, Birgitta E Michels, Thomas Magg, Yue Li, Yanshan Liu, Maryam Ghalandary, Katja Lammens, Sebastian Hollizeck, Meino Rohlfs, Fabian Hauck, Raffaele Conca, Christoph Walz, Batia Weiss, Atar Lev, Amos J Simon, Olaf Groß, Moritz M Gaidt, Veit HornungHans Clevers, Nadine Yazbeck, Rima Hanna-Wakim, Dror S Shouval, Neil Warner, Raz Somech, Aleixo M Muise, Scott B Snapper, Philip Bufler, Sibylle Koletzko, Christoph Klein, Daniel Kotlarz

Research output: Contribution to journal/periodicalArticleScientificpeer-review

92 Citations (Scopus)
Original languageEnglish
Pages (from-to)275-278
Number of pages4
JournalGastroenterology
Volume156
Issue number1
DOIs
Publication statusPublished - Jan 2019

Keywords

  • Age of Onset
  • Animals
  • Apoptosis
  • Autoimmune Lymphoproliferative Syndrome/genetics
  • Biopsy
  • Caspase 8/genetics
  • Colitis, Ulcerative/genetics
  • Endoscopy, Gastrointestinal
  • Epithelial Cells/immunology
  • Genetic Predisposition to Disease
  • Heredity
  • Humans
  • Inflammasomes/immunology
  • Inflammation Mediators/immunology
  • Intestines/immunology
  • Lymphocytes/immunology
  • Mice, Knockout
  • Mutation
  • Phenotype

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