Intron-encoded ribosomal proteins and N-acetyltransferases within the mitochondrial genomes of fungi: here today, gone tomorrow?

Alvan Wai, Chen Shen, Andrell Carta, Alexandra Dansen, Pedro W. Crous, Georg Hausner

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Abstract

In the mitochondrial genomes of the filamentous Ascomycota, aside from the usual ‘core’ set of genes, one can encounter genes encoding for ribosomal protein S3 (rps3), N-acetyltransferase, and in a few instances aminotransferases. Based on a survey using sequence data from various databases, it was observed that these genes can be located within introns or exist as freestanding genes in intergenic regions. Furthermore, they can also be absent from fungal mitochondrial genomes. The rps3 gene is highly conserved among fungal mitochondrial genomes although examples were noted where the mtDNA version of this gene has been translocated into the nuclear genome. The N-acetyltransferase gene was less frequently encountered and may be a more recent import from the nuclear genome. Both genes serve as examples of genetic elements that appear to be capable of ‘cycling’ or mobilizing between introns and intergenic regions and possible between the nuclear and mitochondrial genomes. This ‘cycling’ mechanism is currently not understood but may involve recombination events and/or movement via RNA intermediates.
Original languageEnglish
Pages (from-to)573-584
Number of pages12
JournalMitochondrial DNA Part A
Volume30
Issue number3
DOIs
Publication statusPublished - Mar 2019

Keywords

  • Ascomycotina
  • rps3
  • group I introns
  • mobile elements

Fingerprint Dive into the research topics of 'Intron-encoded ribosomal proteins and N-acetyltransferases within the mitochondrial genomes of fungi: here today, gone tomorrow?'. Together they form a unique fingerprint.

Cite this