Abstract
Cancer cells often trigger an inflammatory process, which in some cases may be driven by the presence of lysyl-tRNA synthetase (KRS) in the medium. Kim et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201605118) now demonstrate that cleavage of the KRS by caspase-8 inside cells triggers its interaction with syntenin and its release in inflammatory exosomes.
Original language | English |
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Pages (from-to) | 1891-1893 |
Number of pages | 3 |
Journal | Journal of Cell Biology |
Volume | 216 |
Issue number | 7 |
DOIs | |
Publication status | Published - 03 Jul 2017 |
Keywords
- Caspase 8
- Exosomes
- Humans
- Lysine-tRNA Ligase
- Journal Article