KRS: A cut away from release in exosomes

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Abstract

Cancer cells often trigger an inflammatory process, which in some cases may be driven by the presence of lysyl-tRNA synthetase (KRS) in the medium. Kim et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201605118) now demonstrate that cleavage of the KRS by caspase-8 inside cells triggers its interaction with syntenin and its release in inflammatory exosomes.

Original languageEnglish
Pages (from-to)1891-1893
Number of pages3
JournalJournal of Cell Biology
Volume216
Issue number7
DOIs
Publication statusPublished - 03 Jul 2017

Keywords

  • Caspase 8
  • Exosomes
  • Humans
  • Lysine-tRNA Ligase
  • Journal Article

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