KRS: A cut away from release in exosomes

Catherine Rabouille

doi:10.1083/jcb.201706039

KRS: A cut away from release in exosomes

Catherine Rabouille

Hubrecht Institute

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

Abstract

Cancer cells often trigger an inflammatory process, which in some cases may be driven by the presence of lysyl-tRNA synthetase (KRS) in the medium. Kim et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201605118) now demonstrate that cleavage of the KRS by caspase-8 inside cells triggers its interaction with syntenin and its release in inflammatory exosomes.

Original language	English
Pages (from-to)	1891-1893
Number of pages	3
Journal	Journal of Cell Biology
Volume	216
Issue number	7
DOIs	https://doi.org/10.1083/jcb.201706039
Publication status	Published - 03 Jul 2017

Keywords

Caspase 8
Exosomes
Humans
Lysine-tRNA Ligase
Journal Article

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10.1083/jcb.201706039

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title = "KRS: A cut away from release in exosomes",

abstract = "Cancer cells often trigger an inflammatory process, which in some cases may be driven by the presence of lysyl-tRNA synthetase (KRS) in the medium. Kim et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201605118) now demonstrate that cleavage of the KRS by caspase-8 inside cells triggers its interaction with syntenin and its release in inflammatory exosomes.",

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KW - Caspase 8

KW - Exosomes

KW - Humans

KW - Lysine-tRNA Ligase

KW - Journal Article

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DO - 10.1083/jcb.201706039

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KRS: A cut away from release in exosomes

Abstract

Keywords

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