Lineages Within the Trichophyton rubrum Complex

Ann Packeu; Dirk Stubbe; Sam Roesems; Karine Goens; Pascale Van Rooij; Sybren de Hoog; Marijke Hendrickx

doi:10.1007/s11046-019-00386-z

Lineages Within the Trichophyton rubrum Complex

Ann Packeu, Dirk Stubbe, Sam Roesems, Karine Goens, Pascale Van Rooij, Sybren de Hoog, Marijke Hendrickx

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

15 Citations (Scopus)

Abstract

The most important species of the Trichophyton rubrum group are T. rubrum, causing mainly skin and nail infections, and T. violaceum which is mostly scalp-associated. The status of a third species, T. soudanense, has been under debate. With a polyphasic approach, using molecular phylogenetic techniques, MALDI-TOF mass spectrometry and physiological and morphological analysis, we re-evaluated the T. rubrum complex. Our results support four genetic lineages within the complex each with a distinct morphology and identifiable via MALDI-TOF MS: T. rubrum, T. violaceum, T. soudanense and the T. yaoundei clade. However, ITS and Bt2 sequencing data could not confirm these taxa as four monophyletic species. Our results also suggest that strains formerly identified as T. kuryangei and T. megninii should be considered in future taxonomic studies.

Original language	English
Journal	Mycopathologia
DOIs	https://doi.org/10.1007/s11046-019-00386-z
Publication status	Published - 11 Oct 2019

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title = "Lineages Within the Trichophyton rubrum Complex",

abstract = "The most important species of the Trichophyton rubrum group are T. rubrum, causing mainly skin and nail infections, and T. violaceum which is mostly scalp-associated. The status of a third species, T. soudanense, has been under debate. With a polyphasic approach, using molecular phylogenetic techniques, MALDI-TOF mass spectrometry and physiological and morphological analysis, we re-evaluated the T. rubrum complex. Our results support four genetic lineages within the complex each with a distinct morphology and identifiable via MALDI-TOF MS: T. rubrum, T. violaceum, T. soudanense and the T. yaoundei clade. However, ITS and Bt2 sequencing data could not confirm these taxa as four monophyletic species. Our results also suggest that strains formerly identified as T. kuryangei and T. megninii should be considered in future taxonomic studies.",

author = "Ann Packeu and Dirk Stubbe and Sam Roesems and Karine Goens and {Van Rooij}, Pascale and {de Hoog}, Sybren and Marijke Hendrickx",

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doi = "10.1007/s11046-019-00386-z",

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T1 - Lineages Within the Trichophyton rubrum Complex

AU - Packeu, Ann

AU - Stubbe, Dirk

AU - Roesems, Sam

AU - Goens, Karine

AU - Van Rooij, Pascale

AU - de Hoog, Sybren

AU - Hendrickx, Marijke

PY - 2019/10/11

Y1 - 2019/10/11

N2 - The most important species of the Trichophyton rubrum group are T. rubrum, causing mainly skin and nail infections, and T. violaceum which is mostly scalp-associated. The status of a third species, T. soudanense, has been under debate. With a polyphasic approach, using molecular phylogenetic techniques, MALDI-TOF mass spectrometry and physiological and morphological analysis, we re-evaluated the T. rubrum complex. Our results support four genetic lineages within the complex each with a distinct morphology and identifiable via MALDI-TOF MS: T. rubrum, T. violaceum, T. soudanense and the T. yaoundei clade. However, ITS and Bt2 sequencing data could not confirm these taxa as four monophyletic species. Our results also suggest that strains formerly identified as T. kuryangei and T. megninii should be considered in future taxonomic studies.

AB - The most important species of the Trichophyton rubrum group are T. rubrum, causing mainly skin and nail infections, and T. violaceum which is mostly scalp-associated. The status of a third species, T. soudanense, has been under debate. With a polyphasic approach, using molecular phylogenetic techniques, MALDI-TOF mass spectrometry and physiological and morphological analysis, we re-evaluated the T. rubrum complex. Our results support four genetic lineages within the complex each with a distinct morphology and identifiable via MALDI-TOF MS: T. rubrum, T. violaceum, T. soudanense and the T. yaoundei clade. However, ITS and Bt2 sequencing data could not confirm these taxa as four monophyletic species. Our results also suggest that strains formerly identified as T. kuryangei and T. megninii should be considered in future taxonomic studies.

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DO - 10.1007/s11046-019-00386-z

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SN - 0301-486X

JO - Mycopathologia

JF - Mycopathologia

ER -

Lineages Within the Trichophyton rubrum Complex

Abstract

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