Lumbar drainage for the treatment of refractory intracranial hypertension in HIV-negative cryptococcal meningitis

Qilong Zhang; Hang Li; Keming Zhang; Amir Arastehfar; Farnaz Daneshnia; Wenjie Fang; Peijuan He; Weifeng Kuang; Guoqiang Jiang; Min Chen; Teun Boekhout; Shuai Li; Weiwei Jiang; Wanqing Liao; Weihua Pan

doi:10.2217/fmb-2019-0084

Lumbar drainage for the treatment of refractory intracranial hypertension in HIV-negative cryptococcal meningitis

Qilong Zhang, Hang Li, Keming Zhang, Amir Arastehfar, Farnaz Daneshnia, Wenjie Fang, Peijuan He, Weifeng Kuang, Guoqiang Jiang, Min Chen, Teun Boekhout, Shuai Li, Weiwei Jiang, Wanqing Liao, Weihua Pan

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

9 Citations (Scopus)

Abstract

Aim: This study aims to evaluate lumbar drainage (LD) for controlling refractory intracranial hypertension among non-HIV cryptococcal meningitis patients. Patients & methods: A case-control study was designed to compare LD (case) with repeated lumbar puncture (control). Results: Both LD and repeated lumbar puncture can efficiently control refractory intracranial hypertension. LD group showed better clinical symptom remission, such as lower rate of headache, vision disorders, signs of meningeal irritation and conscious disturbance, than control group. LD group was reported with higher intracranial pressure reduction (173.75 ± 17.72 mmH2O) than those among control group (113.50 ± 14.94 mmH2O; p < 0.05). Conclusion: LD is an effective and safe alternative to control refractory intracranial hypertension in HIV-negative cryptococcal meningitis patients.

Original language	English
Pages (from-to)	859-866
Number of pages	8
Journal	Future Microbiology
Volume	14
DOIs	https://doi.org/10.2217/fmb-2019-0084
Publication status	Published - Jul 2019

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title = "Lumbar drainage for the treatment of refractory intracranial hypertension in HIV-negative cryptococcal meningitis",

abstract = "Aim: This study aims to evaluate lumbar drainage (LD) for controlling refractory intracranial hypertension among non-HIV cryptococcal meningitis patients. Patients & methods: A case-control study was designed to compare LD (case) with repeated lumbar puncture (control). Results: Both LD and repeated lumbar puncture can efficiently control refractory intracranial hypertension. LD group showed better clinical symptom remission, such as lower rate of headache, vision disorders, signs of meningeal irritation and conscious disturbance, than control group. LD group was reported with higher intracranial pressure reduction (173.75 ± 17.72 mmH2O) than those among control group (113.50 ± 14.94 mmH2O; p < 0.05). Conclusion: LD is an effective and safe alternative to control refractory intracranial hypertension in HIV-negative cryptococcal meningitis patients.",

author = "Qilong Zhang and Hang Li and Keming Zhang and Amir Arastehfar and Farnaz Daneshnia and Wenjie Fang and Peijuan He and Weifeng Kuang and Guoqiang Jiang and Min Chen and Teun Boekhout and Shuai Li and Weiwei Jiang and Wanqing Liao and Weihua Pan",

year = "2019",

month = jul,

doi = "10.2217/fmb-2019-0084",

language = "English",

volume = "14",

pages = "859--866",

journal = "Future Microbiology",

issn = "1746-0913",

publisher = "Future Medicine Ltd.",

}

TY - JOUR

T1 - Lumbar drainage for the treatment of refractory intracranial hypertension in HIV-negative cryptococcal meningitis

AU - Zhang, Qilong

AU - Li, Hang

AU - Zhang, Keming

AU - Arastehfar, Amir

AU - Daneshnia, Farnaz

AU - Fang, Wenjie

AU - He, Peijuan

AU - Kuang, Weifeng

AU - Jiang, Guoqiang

AU - Chen, Min

AU - Boekhout, Teun

AU - Li, Shuai

AU - Jiang, Weiwei

AU - Liao, Wanqing

AU - Pan, Weihua

PY - 2019/7

Y1 - 2019/7

N2 - Aim: This study aims to evaluate lumbar drainage (LD) for controlling refractory intracranial hypertension among non-HIV cryptococcal meningitis patients. Patients & methods: A case-control study was designed to compare LD (case) with repeated lumbar puncture (control). Results: Both LD and repeated lumbar puncture can efficiently control refractory intracranial hypertension. LD group showed better clinical symptom remission, such as lower rate of headache, vision disorders, signs of meningeal irritation and conscious disturbance, than control group. LD group was reported with higher intracranial pressure reduction (173.75 ± 17.72 mmH2O) than those among control group (113.50 ± 14.94 mmH2O; p < 0.05). Conclusion: LD is an effective and safe alternative to control refractory intracranial hypertension in HIV-negative cryptococcal meningitis patients.

AB - Aim: This study aims to evaluate lumbar drainage (LD) for controlling refractory intracranial hypertension among non-HIV cryptococcal meningitis patients. Patients & methods: A case-control study was designed to compare LD (case) with repeated lumbar puncture (control). Results: Both LD and repeated lumbar puncture can efficiently control refractory intracranial hypertension. LD group showed better clinical symptom remission, such as lower rate of headache, vision disorders, signs of meningeal irritation and conscious disturbance, than control group. LD group was reported with higher intracranial pressure reduction (173.75 ± 17.72 mmH2O) than those among control group (113.50 ± 14.94 mmH2O; p < 0.05). Conclusion: LD is an effective and safe alternative to control refractory intracranial hypertension in HIV-negative cryptococcal meningitis patients.

U2 - 10.2217/fmb-2019-0084

DO - 10.2217/fmb-2019-0084

M3 - Article

C2 - 31165635

SN - 1746-0913

VL - 14

SP - 859

EP - 866

JO - Future Microbiology

JF - Future Microbiology

ER -

Lumbar drainage for the treatment of refractory intracranial hypertension in HIV-negative cryptococcal meningitis

Abstract

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