Major construction entails major demolition

Ekaterina Korotkevich; Takashi Hiiragi

doi:10.1016/j.devcel.2022.05.008

Major construction entails major demolition

Ekaterina Korotkevich, Takashi Hiiragi

Hubrecht Institute

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

Abstract

Embryonic cells of the early mouse embryo become hypersensitive to apoptotic stimuli before gastrulation. In this issue of Developmental Cell, Pernaute et al. show that this switch in sensitivity is a result of a change in mitochondrial dynamics and mitophagy levels controlled by DRP1, a regulator of mitochondrial fission.

Original language	English
Pages (from-to)	1311-1313
Number of pages	3
Journal	Developmental Cell
Volume	57
Issue number	11
DOIs	https://doi.org/10.1016/j.devcel.2022.05.008
Publication status	Published - 06 Jun 2022

Keywords

Animals
Dynamins
Mice
Mitochondrial Dynamics
Mitochondrial Proteins
Mitophagy

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10.1016/j.devcel.2022.05.008

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title = "Major construction entails major demolition",

abstract = "Embryonic cells of the early mouse embryo become hypersensitive to apoptotic stimuli before gastrulation. In this issue of Developmental Cell, Pernaute et al. show that this switch in sensitivity is a result of a change in mitochondrial dynamics and mitophagy levels controlled by DRP1, a regulator of mitochondrial fission.",

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author = "Ekaterina Korotkevich and Takashi Hiiragi",

year = "2022",

month = jun,

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doi = "10.1016/j.devcel.2022.05.008",

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T1 - Major construction entails major demolition

AU - Korotkevich, Ekaterina

AU - Hiiragi, Takashi

PY - 2022/6/6

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AB - Embryonic cells of the early mouse embryo become hypersensitive to apoptotic stimuli before gastrulation. In this issue of Developmental Cell, Pernaute et al. show that this switch in sensitivity is a result of a change in mitochondrial dynamics and mitophagy levels controlled by DRP1, a regulator of mitochondrial fission.

KW - Animals

KW - Dynamins

KW - Mice

KW - Mitochondrial Dynamics

KW - Mitochondrial Proteins

KW - Mitophagy

U2 - 10.1016/j.devcel.2022.05.008

DO - 10.1016/j.devcel.2022.05.008

M3 - Article

C2 - 35671703

SN - 1534-5807

VL - 57

SP - 1311

EP - 1313

JO - Developmental Cell

JF - Developmental Cell

IS - 11

ER -

Major construction entails major demolition

Abstract

Keywords

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