Malassezia spp. Yeasts of Emerging Concern in Fungemia

Wafa Rhimi; Bart Theelen; Teun Boekhout; Domenico Otranto; Claudia Cafarchia

doi:10.3389/fcimb.2020.00370

Malassezia spp. Yeasts of Emerging Concern in Fungemia

Wafa Rhimi, Bart Theelen, Teun Boekhout, Domenico Otranto, Claudia Cafarchia

Research output: Contribution to journal/periodical › Book/Film/Article review › Scientific

62 Citations (Scopus)

Abstract

Malassezia spp. are lipid-dependent yeasts, inhabiting the skin and mucosa of humans and animals. They are involved in a variety of skin disorders in humans and animals and may cause bloodstream infections in severely immunocompromised patients. Despite a tremendous increase in scientific knowledge of these yeasts during the last two decades, the epidemiology of Malassezia spp. related to fungemia remains largely underestimated most likely due to the difficulty in the isolation of these yeasts species due to their lipid-dependence. This review summarizes and discusses the most recent literature on Malassezia spp. infection and fungemia, its occurrence, pathogenicity mechanisms, diagnostic methods, in vitro susceptibility testing and therapeutic approaches.

Original language	English
Pages (from-to)	370
Journal	Frontiers in cellular and infection microbiology
Volume	10
DOIs	https://doi.org/10.3389/fcimb.2020.00370
Publication status	Published - 28 Jul 2020

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title = "Malassezia spp. Yeasts of Emerging Concern in Fungemia",

abstract = "Malassezia spp. are lipid-dependent yeasts, inhabiting the skin and mucosa of humans and animals. They are involved in a variety of skin disorders in humans and animals and may cause bloodstream infections in severely immunocompromised patients. Despite a tremendous increase in scientific knowledge of these yeasts during the last two decades, the epidemiology of Malassezia spp. related to fungemia remains largely underestimated most likely due to the difficulty in the isolation of these yeasts species due to their lipid-dependence. This review summarizes and discusses the most recent literature on Malassezia spp. infection and fungemia, its occurrence, pathogenicity mechanisms, diagnostic methods, in vitro susceptibility testing and therapeutic approaches.",

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AU - Rhimi, Wafa

AU - Theelen, Bart

AU - Boekhout, Teun

AU - Otranto, Domenico

AU - Cafarchia, Claudia

PY - 2020/7/28

Y1 - 2020/7/28

N2 - Malassezia spp. are lipid-dependent yeasts, inhabiting the skin and mucosa of humans and animals. They are involved in a variety of skin disorders in humans and animals and may cause bloodstream infections in severely immunocompromised patients. Despite a tremendous increase in scientific knowledge of these yeasts during the last two decades, the epidemiology of Malassezia spp. related to fungemia remains largely underestimated most likely due to the difficulty in the isolation of these yeasts species due to their lipid-dependence. This review summarizes and discusses the most recent literature on Malassezia spp. infection and fungemia, its occurrence, pathogenicity mechanisms, diagnostic methods, in vitro susceptibility testing and therapeutic approaches.

AB - Malassezia spp. are lipid-dependent yeasts, inhabiting the skin and mucosa of humans and animals. They are involved in a variety of skin disorders in humans and animals and may cause bloodstream infections in severely immunocompromised patients. Despite a tremendous increase in scientific knowledge of these yeasts during the last two decades, the epidemiology of Malassezia spp. related to fungemia remains largely underestimated most likely due to the difficulty in the isolation of these yeasts species due to their lipid-dependence. This review summarizes and discusses the most recent literature on Malassezia spp. infection and fungemia, its occurrence, pathogenicity mechanisms, diagnostic methods, in vitro susceptibility testing and therapeutic approaches.

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JO - Frontiers in cellular and infection microbiology

JF - Frontiers in cellular and infection microbiology

ER -

Malassezia spp. Yeasts of Emerging Concern in Fungemia

Abstract

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