Malassezia spp. Yeasts of Emerging Concern in Fungemia

Wafa Rhimi, Bart Theelen, Teun Boekhout, Domenico Otranto, Claudia Cafarchia

Research output: Contribution to journal/periodicalBook/Film/Article reviewScientific

50 Citations (Scopus)

Abstract

Malassezia spp. are lipid-dependent yeasts, inhabiting the skin and mucosa of humans and animals. They are involved in a variety of skin disorders in humans and animals and may cause bloodstream infections in severely immunocompromised patients. Despite a tremendous increase in scientific knowledge of these yeasts during the last two decades, the epidemiology of Malassezia spp. related to fungemia remains largely underestimated most likely due to the difficulty in the isolation of these yeasts species due to their lipid-dependence. This review summarizes and discusses the most recent literature on Malassezia spp. infection and fungemia, its occurrence, pathogenicity mechanisms, diagnostic methods, in vitro susceptibility testing and therapeutic approaches.

Original languageEnglish
Pages (from-to)370
JournalFrontiers in cellular and infection microbiology
Volume10
DOIs
Publication statusPublished - 28 Jul 2020

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