Abstract
By beautiful imaging and state-of-the-art experiments, vinculin is established to be a central switch in mechanotransduction at integrin-based focal adhesions. Cycles of tension-regulated vinculin switching control focal adhesion dynamics and signaling to enable polarized cell migration and alignment.
Original language | English |
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Pages (from-to) | 159-161 |
Journal | Current Biology |
Volume | 23 |
Issue number | 4 |
DOIs | |
Publication status | Published - 2013 |