Abstract
Classically, we think of cell compartmentalization as being achieved by membrane-bound organelles. It has nevertheless emerged that membrane-less assemblies also largely contribute to this compartmentalization. Here, we compare the characteristics of both types of compartmentalization in term of maintenance of functional identities. Furthermore, membrane less-compartments are critical for sustaining developmental and cell biological events as they control major metabolic pathways. We describe two examples related to this issue in Drosophila, the role of P-bodies in the translational control of gurken in the Drosophila oocyte, and the formation of Sec bodies upon amino-acid starvation in Drosophila cells.
| Original language | English |
|---|---|
| Pages (from-to) | 310-317 |
| Number of pages | 8 |
| Journal | Developmental Biology |
| Volume | 428 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - 15 Aug 2017 |
Keywords
- Animals
- Cell Compartmentation
- Drosophila Proteins
- Drosophila melanogaster
- Female
- Genes, Insect
- Membranes
- Metabolic Networks and Pathways
- Models, Biological
- Oocytes
- Organelles
- SEC Translocation Channels
- Transforming Growth Factor alpha
- Journal Article
- Review
- Research Support, Non-U.S. Gov't
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