microRNA-132 attenuates inflammation in induced pluripotent stem cell-derived microglia from Alzheimer's disease patients

Amber Penning; Sarah Snoeck; Olmo Ruiz Ormaechea; Dilara Ayyildiz; Oliver Polzer; Martin Buitrago-Arango; Raffaella Capobianco; Fred de Winter; Sriram Balusu; Joost Verhaagen; Carlos P Fitzsimons; Constantin d'Ydewalle; Paul J Lucassen; Dieder Moechars; Lujia Zhou; Evgenia Salta

doi:10.1186/s40478-026-02228-8

microRNA-132 attenuates inflammation in induced pluripotent stem cell-derived microglia from Alzheimer's disease patients

Amber Penning
, Sarah Snoeck
, Olmo Ruiz Ormaechea
, Dilara Ayyildiz
, Oliver Polzer
, Martin Buitrago-Arango
, Raffaella Capobianco
, Fred de Winter
, Sriram Balusu
, Joost Verhaagen
, Carlos P Fitzsimons
, Constantin d'Ydewalle
, Paul J Lucassen
, Dieder Moechars
, Lujia Zhou
, Evgenia Salta

Research output: Contribution to journal/periodical › Article › Scientific › peer-review

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Original language	English
Article number	99
Journal	Acta neuropathologica communications
Volume	14
DOIs	https://doi.org/10.1186/s40478-026-02228-8
Publication status	Published - 07 Mar 2026

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10.1186/s40478-026-02228-8

Penning2026Final published version, 3.16 MB

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Penning, A., Snoeck, S., Ormaechea, O. R., Ayyildiz, D., Polzer, O., Buitrago-Arango, M., Capobianco, R., de Winter, F., Balusu, S., Verhaagen, J., Fitzsimons, C. P., d'Ydewalle, C., Lucassen, P. J., Moechars, D., Zhou, L., & Salta, E. (2026). microRNA-132 attenuates inflammation in induced pluripotent stem cell-derived microglia from Alzheimer's disease patients. Acta neuropathologica communications, 14, Article 99. https://doi.org/10.1186/s40478-026-02228-8

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author = "Amber Penning and Sarah Snoeck and Ormaechea, \{Olmo Ruiz\} and Dilara Ayyildiz and Oliver Polzer and Martin Buitrago-Arango and Raffaella Capobianco and \{de Winter\}, Fred and Sriram Balusu and Joost Verhaagen and Fitzsimons, \{Carlos P\} and Constantin d'Ydewalle and Lucassen, \{Paul J\} and Dieder Moechars and Lujia Zhou and Evgenia Salta",

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Penning, A, Snoeck, S, Ormaechea, OR, Ayyildiz, D, Polzer, O, Buitrago-Arango, M, Capobianco, R, de Winter, F, Balusu, S, Verhaagen, J, Fitzsimons, CP, d'Ydewalle, C, Lucassen, PJ, Moechars, D, Zhou, L & Salta, E 2026, 'microRNA-132 attenuates inflammation in induced pluripotent stem cell-derived microglia from Alzheimer's disease patients', Acta neuropathologica communications, vol. 14, 99. https://doi.org/10.1186/s40478-026-02228-8

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AU - Penning, Amber

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AU - Ormaechea, Olmo Ruiz

AU - Ayyildiz, Dilara

AU - Polzer, Oliver

AU - Buitrago-Arango, Martin

AU - Capobianco, Raffaella

AU - de Winter, Fred

AU - Balusu, Sriram

AU - Verhaagen, Joost

AU - Fitzsimons, Carlos P

AU - d'Ydewalle, Constantin

AU - Lucassen, Paul J

AU - Moechars, Dieder

AU - Zhou, Lujia

AU - Salta, Evgenia

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JO - Acta neuropathologica communications

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