Microwell Scaffolds Using Collagen-IV and Laminin-111 Lead to Improved Insulin Secretion of Human Islets

Elahe Hadavi, Jeroen Leijten, Marten Engelse, Eelco de Koning, Pascal Jonkheijm, Marcel Karperien, Aart van Apeldoorn

Research output: Contribution to journal/periodicalArticleScientificpeer-review

Abstract

IMPACT STATEMENT: This research deals with finding a proper bioengineering strategy to improve the outcome of islets transplantation for treatment of type 1 diabetes. It is focused on the mimicking of islet extracellular matrix niche in microwell islet delivery devices to improve their endocrine function.

Original languageEnglish
Pages (from-to)71-81
Number of pages11
JournalTissue Engineering - Part C: Methods
Volume25
Issue number2
DOIs
Publication statusPublished - Feb 2019

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